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Correction to: Measuring Overall Severity of Myasthenia Gravis (MG): Evidence for the Added Value of the MG Symptoms PRO
Springer Science and Business Media LLC - Tập 12 - Trang 1591-1592 - 2023
Antoine Regnault, Thomas Morel, Christine de la Loge, Flora Mazerolle, Henry J. Kaminski, Ali A. Habib
Pharmacokinetics and Comparative Bioavailability of Apomorphine Sublingual Film and Subcutaneous Apomorphine Formulations in Patients with Parkinson’s Disease and “OFF” Episodes: Results of a Randomized, Three-Way Crossover, Open-Label Study
Springer Science and Business Media LLC - - 2021
Felix Agbo, Stuart H. Isaacson, Ramon Gil, Yu-Yuan Chiu, Scott J. Brantley, Parul Bhargava, Bradford Navia
In a pivotal study, apomorphine sublingual film (APL; KYNMOBI®) was an effective and generally well-tolerated on-demand treatment of “OFF” episodes in patients with Parkinson’s disease (PD), approved across the dose range of 10–30 mg. Pharmacokinetics and comparative bioavailability of APL and two subcutaneous (SC) apomorphine formulations (SC-APO [APOKYN®] and SC-APO-GO [APO-go® PEN]) were evalua...... hiện toàn bộ
Management of Migraine and the Accessibility of Specialist Care: Findings from an Extended Multinational Survey (My Migraine Center Survey)
Springer Science and Business Media LLC - Tập 9 - Trang 551-565 - 2020
Siriporn Wongsiriroj, Elisabetta Grillo, Sabrina Levi, Ronald Zielman, Elia Lahouiri, Marco Marchina, Marco Pedrazzoli, Matias Ferraris
The parent study was a survey in 28 headache centers (6 countries) which identified five potential root causes for long waiting lists that limit patient access to specialist care. Here we performed an extension of the parent study to increase the panel of centers contacted, the representativeness of the analysis, and the statistical validity of the results, and to explore the role of dedicated hea...... hiện toàn bộ
Cladribine Tablets Mode of Action, Learning from the Pandemic: A Narrative Review
Springer Science and Business Media LLC - Tập 12 - Trang 1477-1490 - 2023
Federico Carlini, Valeria Lusi, Caterina Rizzi, Francesco Assogna, Alice Laroni
Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system, characterized by chronic, inflammatory, demyelinating, and neurodegenerative processes. MS management relies on disease-modifying drugs that suppress/modulate the immune system. Cladribine tablets (CladT) have been approved by different health authorities for patients with various forms of relapsing MS. The drug h...... hiện toàn bộ
Multiple Sclerosis in Pregnancy: A Commentary on Disease Modification and Symptomatic Drug Therapies
Springer Science and Business Media LLC - Tập 12 Số 1 - Trang 1-10 - 2023
Iyer, Priyanka, Dobson, Ruth
Multiple sclerosis (MS) frequently affects women of childbearing age, and an increasing number of disease-modifying therapies are available. However, a consequence of this is that women and clinicians face complex shared decisions surrounding disease-modifying therapy use in pregnancy and postpartum. It has been suggested that there are both knowledge and communication gaps that need to be ad...... hiện toàn bộ
Long-Term Effectiveness, Safety and Tolerability of Fingolimod in Patients with Multiple Sclerosis in Real-World Treatment Settings in France: The VIRGILE Study
Springer Science and Business Media LLC - Tập 11 - Trang 633-658 - 2022
Caroline Papeix, Giovanni Castelnovo, Emmanuelle Leray, Marc Coustans, Pierre Levy, Jean-Marc Visy, Gisela Kobelt, Fabienne Lamy, Bashar Allaf, François Heintzmann, Isabelle Chouette, Eric Raponi, Barbara Durand, Emmanuelle Grevat, Driss Kamar, Marc Debouverie, Christine Lebrun-Frenay
It is important to confirm the effectiveness and tolerability of disease-modifying treatments for relapsing–remitting multiple sclerosis (RRMS) in real-world treatment settings. This prospective observational cohort study (VIRGILE) was performed at the request of the French health authorities. The primary objective was to evaluate the effectiveness of fingolimod 0.5 mg in reducing the annualised r...... hiện toàn bộ
Parkinson’s Disease, the Dopaminergic Neuron and Gammahydroxybutyrate
Springer Science and Business Media LLC - - 2018
Mortimer Mamelak
The Clinical Development of Taldefgrobep Alfa: An Anti-Myostatin Adnectin for the Treatment of Duchenne Muscular Dystrophy
Springer Science and Business Media LLC - - 2024
Francesco Muntoni, Barry J. Byrne, Hugh J. McMillan, Monique M. Ryan, Brenda Wong, Juergen Dukart, Amita Bansal, Valérie Cosson, Roxana Donisa Dreghici, Maitea Guridi, Michael Rabbia, Hannah Staunton, Giridhar Tirucherai, Karl Yen, Xiling Yuan, Kathryn R. Wagner, Irvith M. Carvajal, Anjaneya Chimalakonda, Jochem Gokemeijer, Michael Gulianello, Nicole Hellbach, Alexander Kozhich, Daniel Kukral, Harold Malone, Jere E. Meredith, Mathew T. Pletcher, Ginger Rakestraw, Lumelle A. Schneeweis, Judith L. Swain, Frank Zambito, Ming Chang, Lora Hamuro, Feng Luo, Julie Peterson, Peter Hocknell, Zhen Lou, Malavi T. Madireddi, Clifford Bechtold, Michael K. Ahlijanian, Leslie K. Jacobsen, Heidemarie Kletzl, Alberto Dubrovsky, L. Mesa, Fernando Chloca, Agustin Jauregu, Kristi Jones, Craig Campbell, Jean K. Mah, Alice Y. Ho, Angela W. Chiu, Vanessa D’Souza, R Sadowski, Julie Dao, M. Edward Grice, Tiffany Price, Hugh J. McMillan, Erick Sell, Anna McCormick, Teresa Gidaro, Andrea Seferian, Yann Péreón, Armelle Magot, Carole Vuillerot, Ulrike Schara‐Schmidt, Valeria Sansone, Emilio Albamonte, Alessandra Di Bari, Jasmine Refran, Francesca Salmin, Giuseppe Vita, Gian Luca Vita, Chiara Consulo, Hirofumi Komaki, Akihiko Ishiyama, Tsuyoshi Matsumura, Toshio Saitô, Kiyoshi Ichihara, Naoki Hayashi, Kensuke Terada, Kenji Takehara, Nobuko Hayashi, Yasuhiro Takeshima, Andrés Nascimiento, Daniel Natera-de Benito, L. Carrera, Jessica Expósito‐Escudero, Carlos Ortez, J. Medina, O. Moya, S. Roca, Alicia Rodríguez, M. Valle, I. de Groot, Erik H. Niks, Marjolein J. van Heur-Neuman, Menno van der Holst, Mariacristina Scoto, Chiara Brusa, Abidha Afazal, Elka Miller, Linda Cripe, Richard S. Finkel, Peter Heydemann, Katherine Matthews, Chandra Miller, Katie Laubsher, Shelley Mockeler, Han Phan, Kumaraswamy Sivakumar, Kristy Osgood, Jeffrey Statland, Chengming Tian, Doris Leung, Genila Bibat, Nikia Stinson, Laurent Servais, Eugenio Mercuri, Tina Duong, Paul Strijbos, Klaas Veenstra
Neurophysiological Markers of Alzheimer’s Disease: Quantitative EEG Approach
Springer Science and Business Media LLC - Tập 8 - Trang 37-55 - 2019
Una Smailovic, Vesna Jelic
Currently established and employed biomarkers of Alzheimer's disease (AD) predominantly mirror AD-associated molecular and structural brain changes. While they are necessary for identifying disease-specific neuropathology, they lack a clear and robust relationship with the clinical presentation of dementia; they can be altered in healthy individuals, while they often inadequately mirror the degree...... hiện toàn bộ
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