The NLRP3 Inflammasome in Alcoholic and Nonalcoholic SteatohepatitisSeminars in Liver Disease - Tập 40 Số 03 - Trang 298-306 - 2020
Jana Knorr, Alexander Wree, Frank Tacke, Ariel E. Feldstein
AbstractNonalcoholic steatohepatitis (NASH) and alcoholic hepatitis (ASH) are advanced forms of fatty liver diseases that are associated with a high morbidity and mortality worldwide. Patients with ASH or NASH are more susceptible to the progression of fibrosis and cirrhosis up to the development of hepatocellular carcinoma. Currently, there are limited medical the...... hiện toàn bộ
Noninvasive Diagnostics for Portal Hypertension: A Comprehensive ReviewSeminars in Liver Disease - Tập 40 Số 03 - Trang 240-255 - 2020
Mattias Mandorfer, Jaume Bosch, Juan Carlos García–Pagán, Thomas Reiberger
AbstractNoninvasive diagnostics for portal hypertension include imaging and functional tests, as well as blood-based biomarkers, and capture different features of the portal hypertensive syndrome. Definitive conclusions regarding their clinical utility require assessment of their diagnostic value in specific clinical settings (i.e., diagnosing a particular hemodyna...... hiện toàn bộ
Hepatocellular Carcinoma with Portal Vein Tumor Involvement: Best Management StrategiesSeminars in Liver Disease - Tập 38 Số 03 - Trang 242-251 - 2018
Po‐Hong Liu, Teh‐Ia Huo, Rebecca A. Miksad
AbstractPortal vein tumor thrombosis (PVTT) commonly occurs in patients with hepatocellular carcinoma (HCC). Patients with PVTT usually have an aggressive disease course, decreased liver function reserve, limited treatment options, higher recurrence rates after treatment, and, therefore, worse overall survival. Among untreated HCC patients with PVTT, the median ove...... hiện toàn bộ