SAGE Publications
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Các bài báo tiêu biểu
The Effect of Bacterial Biofilms on Post-sinus Surgical OutcomesBackground Although the existence of biofilms on the sinus mucosa of patients with chronic rhinosinusitis (CRS) is now well established, the role that these structures play remains unclear. It is thought that biofilms may contribute to the recalcitrant and persistent nature that characterizes CRS, but little research exists documenting the effect that the...
Tập 22 Số 1 - Trang 1-6 - 2008
Endoscopic Resection of Malignant Tumors of the Nose and SinusesBackground Since the introduction of endoscopic surgery, its role has been gradually extended to encompass a range of pathologies, including sinonasal tumors, facilitated by the ability to repair significant skull-base defects. However, the rarity and long natural history of malignant tumors make it difficult to accrue cohorts comparable with the establis...
Tập 21 Số 1 - Trang 89-94 - 2007
Prevalence of Biofilm-forming Bacteria in Chronic RhinosinusitisBackground Recently, biofilms have been implicated in the pathogenesis of recalcitrant chronic rhinosinusitis (CRS). We sought to determine the prevalence of biofilm-forming cultures obtained from patients with CRS and clinical factors that may contribute to biofilm formation. Methods Endoscop...
Tập 22 Số 3 - Trang 239-245 - 2008
Demonstration of Biofilm in Human Bacterial Chronic RhinosinusitisBackground Bacterial biofilms may explain why some patients with bacterial chronic rhinosinusitis (CRS) improve while on antibiotics but relapse after completion of the antibiotic. In the human host, biofilms exist as a community of bacteria surrounded by a glycocalyx that is adherent to a foreign body or a mucosal surface with impaired host defense. Biof...
Tập 19 Số 5 - Trang 452-457 - 2005
Effectiveness of Topical Antibiotics on Staphylococcus Aureus Biofilm in VitroBackground In vitro biofilm-producing capacity in isolates of Staphylococcus aureus and Pseudomonas aeruginosa collected from the sinus cavities after endoscopic sinus surgery (ESS) are associated with a poor outcome in patients with chronic rhinosinusitis (CRS). However, conventional oral antibiotic therapy is frequently ineffective in eradicating bacter...
Tập 21 Số 2 - Trang 149-153 - 2007
Topical Application of Mitomycin-C in Endoscopic DacryocystorhinostomyEndoscopic dacryocystorhinostomy (DCR) is a well-established alternative to external DCR for treatment of obstruction of the lacrimal pathway and has a success rate of up to 95% in primary cases. Despite the benefits of using an endoscopic approach, including enhanced intranasal access to the lacrimal drainage system, there still exists a significant failure rate, particularly in revision ... ...
Tập 14 Số 3 - Trang 205-208 - 2000
A Scanning Electron Microscopic Study of Smoking and Age-Related Changes in Human Nasal Epithelium The nose is known to undergo dysfunctional changes as people age, probably due to exposure to agents such as smoking, environmental pollutants, and microbes. A morphologic expression of these insults might be a change in the number of ciliated cells present in the nasal mucosa. This study revealed that smoking and age were not related to a reduction in the number of ciliated cells of the ... ...
Tập 6 Số 5 - Trang 185-190 - 1992