Reviews in Endocrine and Metabolic Disorders

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Metabolic actions of the growth hormone-insulin growth factor-1 axis and its interaction with the central nervous system
Reviews in Endocrine and Metabolic Disorders - Tập 23 - Trang 919-930 - 2022
Omar Al-Massadi, Paolo Parini, Johan Fernø, Serge Luquet, Mar Quiñones
The growth hormone/insulin growth factor-1 axis is a key endocrine system that exerts profound effects on metabolism by its actions on different peripheral tissues but also in the brain. Growth hormone together with insulin growth factor-1 perform metabolic adjustments, including regulation of food intake, energy expenditure, and glycemia. The dysregulation of this hepatic axis leads to different ...... hiện toàn bộ
Primary aldosteronism and a Texas two-step
Reviews in Endocrine and Metabolic Disorders - Tập 12 - Trang 37-42 - 2011
Richard J. Auchus
Primary aldosteronism is unquestionably the most common secondary cause of hypertension, and effective approaches to diagnosis and targeted treatments exist. Even the most conservative estimates of the prevalence of primary aldosteronism, however, indicate that the condition is grossly underdiagnosed. Part of the reason why diagnosis and treatment lag far behind is the lack of expertise, even amon...... hiện toàn bộ
Efficacy and tolerability of somatostatin analogues according to gender in patients with neuroendocrine tumors
Reviews in Endocrine and Metabolic Disorders - - Trang 1-16 - 2023
Rosaria M. Ruggeri, Irene Aini, Stefano Gay, Erika Maria Grossrubatscher, Camilla Mancini, Maria Grazia Tarsitano, Virginia Zamponi, Andrea M. Isidori, Annamaria Colao, Antongiulio Faggiano
As the incidence of neuroendocrine tumors has been rising, gender differences in epidemiology and clinical behavior have emerged, and interest into a gender-driven management of these tumors has grown with the aim to improve survival and quality of life of these patients. Somatostatin Analogues represent the first line of systemic treatment of both functional and non-functional neuroendocrine tumo...... hiện toàn bộ
Conservation in the phylum of the local homology of apolipoproteins with the thyroid hormone plasma carriers
Reviews in Endocrine and Metabolic Disorders - Tập 17 - Trang 537-544 - 2016
Salvatore Benvenga, Fabrizio Guarneri
Thyroxine-binding globulin (TBG), transthyretin (TTR), albumin (HSA), plus other plasmatic proteins, which include apolipoproteins, can bind and transport thyroid hormones (TH). In 1994, a 5-residue motif (Y, L/I/M, X, X, V/L/I) conserved in human TBG, TTR, HSA, and human and animal apolipoproteins was identified. Recently, we noticed that a number of residues upstream and downstream that motif ar...... hiện toàn bộ
Molecular backgrounds of age-related osteoporosis from mouse genetics approaches
Reviews in Endocrine and Metabolic Disorders - - 2007
Hiroshi Kawaguchi
Functions of stem cells of thyroid glands in health and disease
Reviews in Endocrine and Metabolic Disorders - Tập 20 - Trang 187-195 - 2019
Ebtesam A. Al-Suhaimi, Khulood Al-Khater
Thyroid gland has been implicated in the regulation of many functions using endocrine, paracrine and autocrine signals. Functional thyroid follicular cells derived from stem cells attracted a great interest from researchers as a strategy for thyroid’s regenerative therapy. Thyroid has a very low rate of turnover; however, studies showed that the regenerative ability is enhanced following diseases ...... hiện toàn bộ
Ectopic Cushing’s syndrome due to thymic neuroendocrine tumours: a systematic review
Reviews in Endocrine and Metabolic Disorders - Tập 22 - Trang 1041-1056 - 2021
Fernando Guerrero-Pérez, Inmaculada Peiró, Agustina Pia Marengo, Alex Teulé, José Carlos Ruffinelli, Roger Llatjos, Teresa Serrano, Ivan Macia, Nuria Vilarrasa, Pedro Iglesias, Carles Villabona
Knowledge of ectopic Cushing’s syndrome (CS) due to thymic neuroendocrine tumours (NETs) comes from short series or single cases. Our aim is to perform a systematic review using PubMed, Embase, Scopus, Ovid Medline and Biosis Previews of all cases with ectopic CS due to thymic NETs reported in the last 40 years and describe one illustrative patient attended in our institution. Search of literature...... hiện toàn bộ
Correction to: Chemotherapy in NEN: still has a role?
Reviews in Endocrine and Metabolic Disorders - Tập 23 - Trang 1103-1104 - 2022
Paula Espinosa-Olarte, Anna La Salvia, Maria C. Riesco-Martinez, Beatriz Anton-Pascual, Rocio Garcia-Carbonero
Epigenetic regulation of somatostatin and somatostatin receptors in neuroendocrine tumors and other types of cancer
Reviews in Endocrine and Metabolic Disorders - Tập 22 - Trang 495-510 - 2020
M.J. Klomp, S.U. Dalm, M. de Jong, R.A. Feelders, J. Hofland, L.J. Hofland
Both somatostatin (SST) and somatostatin receptors (SSTRs) are proteins with important functions in both physiological tissue and in tumors, particularly in neuroendocrine tumors (NETs). NETs are frequently characterized by high SSTRs expression levels. SST analogues (SSAs) that bind and activate SSTR have anti-proliferative and anti-secretory activity, thereby reducing both the growth as well as ...... hiện toàn bộ
Hypothalamic control of energy and glucose metabolism
Reviews in Endocrine and Metabolic Disorders - Tập 12 - Trang 219-233 - 2011
Stephanie Sisley, Darleen Sandoval
The central nervous system (CNS), generally accepted to regulate energy homeostasis, has been implicated in the metabolic perturbations that either cause or are associated with obesity. Normally, the CNS receives hormonal, metabolic, and neuronal input to assure adequate energy levels and maintain stable energy homeostasis. Recent evidence also supports that the CNS uses these same inputs to regul...... hiện toàn bộ
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