Advancing the understanding of the embryo transcriptome co-regulation using meta-, functional, and gene network analysis toolsReproduction - Tập 135 Số 2 - Trang 213-224 - 2008
Sandra L. Rodriguez‐Zas, Yun Woong Ko, Heather Adams, Bruce R. Southey
Embryo development is a complex process orchestrated by hundreds of genes and influenced by multiple environmental factors. We demonstrate the application of simple and effective meta-study and gene network analyses strategies to characterize the co-regulation of the embryo transcriptome in a systems biology framework. A meta-analysis of nine microarray experiments aimed at characterizing ...... hiện toàn bộ
Current status of sexing mammalian spermatozoaReproduction - Tập 124 Số 6 - Trang 733-743 - 2002
G.E. Seidel, Duane L. Garner
Thousands of offspring have now been produced via artificial insemination with spermatozoa sexed by flow cytometry and cell sorting. We are unaware of any other practical approach to sexing spermatozoa that maintains fertility. Accuracy of sexing usually is 85-95% in most species, but somewhat lower with human spermatozoa. Spermatozoa are sexed in series, one at a time, at routine rates of...... hiện toàn bộ
Changing expression and subcellular distribution of karyopherins during murine oogenesisReproduction - Tập 150 Số 6 - Trang 485-496 - 2015
Bettina P. Mihalas, Patrick Western, Kate L. Loveland, Eileen A. McLaughlin, Janet E. Holt
Mammalian oocyte growth and development is driven by a strict program of gene expression that relies on the timely presence of transcriptional regulators via nuclear pores. By targeting specific cargos for nucleo-cytoplasmic transport, karyopherin (KPN) proteins are key to the relocation of essential transcription factors and chromatin-remodelling factors into and out of the nucleus. Using...... hiện toàn bộ