Protein & Cell

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Memory T cells: strategies for optimizing tumor immunotherapy
Protein & Cell - Tập 11 - Trang 549-564 - 2020
Qingjun Liu, Zhongjie Sun, Ligong Chen
Several studies have demonstrated that memory T cells including stem cell memory (Tscm) T cells and central memory (Tcm) T cells show superior persistence and antitumor immunity compared with effector memory T (Tem) cells and effector T (Teff) cells. Furthermore, the Tcm/Teff ratio has been reported to be a predictive biomarker of immune responses against some tumors. Thus, a system-level understa...... hiện toàn bộ
Structures of the N- and C-terminal domains of MHV-A59 nucleocapsid protein corroborate a conserved RNA-protein binding mechanism in coronavirus
Protein & Cell - - 2010
Yanlin Ma, Xiaofeng Tong, Xiaolei Xu, Xuemei Li, Zhiyong Lou, Zihe Rao
Crystal structure of the African swine fever virus structural protein p35 reveals its role for core shell assembly
Protein & Cell - Tập 11 - Trang 600-605 - 2020
Guobang Li, Dan Fu, Guangshun Zhang, Dongming Zhao, Mingyu Li, Xue Geng, Dongdong Sun, Yuhui Wang, Cheng Chen, Peng Jiao, Lin Cao, Yu Guo, Zihe Rao
Structural studies on MRG701 chromodomain reveal a novel dimerization interface of MRG proteins in green plants
Protein & Cell - Tập 7 - Trang 792-803 - 2016
Yanchao Liu, Hong Wu, Yu Yu, Ying Huang
MRG proteins are conserved during evolution in fungi, flies, mammals and plants, and they can exhibit diversified functions. The animal MRGs were found to form various complexes to activate gene expression. Plant MRG1/2 and MRG702 were reported to be involved in the regulation of flowering time via binding to H3K36me3-marked flowering genes. Herein, we determined the crystal structure of MRG701 ch...... hiện toàn bộ
Meeting report: The second Tianjin Forum on tumor microenvironment, Tianjin, China, June 22–24, 2012
Protein & Cell - Tập 3 - Trang 561-563 - 2012
Qiangzhe Zhang, Lu-Yuan Li
Indiscriminate ssDNA cleavage activity of CRISPR-Cas12a induces no detectable off-target effects in mouse embryos
Protein & Cell - Tập 12 Số 9 - Trang 741-745 - 2021
Yu Wu, Yingsi Zhou, Yajing Liu, Weiwen Ying, Ruiming Lv, Qingjun Zhao, Haibo Zhou, Erwei Zuo, Yidi Sun, Hui Yang, Chunmei Zhou
The impact of acetylation and deacetylation on the p53 pathway
Protein & Cell - - 2011
Christopher L. Brooks, Wei Gu
The p53 tumor suppressor is a sequence-specific transcription factor that undergoes an abundance of post-translational modifications for its regulation and activation. Acetylation of p53 is an important reversible enzymatic process that occurs in response to DNA damage and genotoxic stress and is indispensible for p53 transcriptional activity. p53 was the first non-histone protein shown to be acet...... hiện toàn bộ
Correction to: Glycosylation of dentin matrix protein 1 is a novel key element for astrocyte maturation and BBB integrity
Protein & Cell - - 2018
Bo Jing, Chunxue Zhang, Xianjun Liu, Liqiang Zhou, Jiping Liu, Yinan Yao, Juehua Yu, Yuteng Weng, Min Pan, Jie Liu, Zuolin Wang, Yao Sun, Yi Eve Sun
In the original publication, the label of Fig. 2C should be read as “GFAP/lectin/DAPI” not “DMP1/GFAP/lectin/DAPI”.
The role of Pbx1 in T cells
Protein & Cell - Tập 2 - Trang 946-949 - 2012
Mayami Sengupta, Laurence Morel
Tissue and organ differentiation is tightly controlled to ensure proper development and function of the growing embryo as well as cells such as lymphocytes that differentiate throughout the adult stage. Therefore it is vital that the genes and the protein they encode that are involved in these processes function accurately. Hence, any mutation or error that occurs along the way can result in exten...... hiện toàn bộ
Debao Wang, the founder of nucleic acid biology and industry in People’s Republic of China
Protein & Cell - Tập 12 - Trang 237-239 - 2020
Zhongliang Ma, Xianyi Wang, Yanli Li
Tổng số: 929   
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