Protein & Cell

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Memory T cells: strategies for optimizing tumor immunotherapy
Protein & Cell - Tập 11 - Trang 549-564 - 2020
Qingjun Liu, Zhongjie Sun, Ligong Chen
Several studies have demonstrated that memory T cells including stem cell memory (Tscm) T cells and central memory (Tcm) T cells show superior persistence and antitumor immunity compared with effector memory T (Tem) cells and effector T (Teff) cells. Furthermore, the Tcm/Teff ratio has been reported to be a predictive biomarker of immune responses against some tumors. Thus, a system-level understa...... hiện toàn bộ
The role of Pbx1 in T cells
Protein & Cell - Tập 2 - Trang 946-949 - 2012
Mayami Sengupta, Laurence Morel
Tissue and organ differentiation is tightly controlled to ensure proper development and function of the growing embryo as well as cells such as lymphocytes that differentiate throughout the adult stage. Therefore it is vital that the genes and the protein they encode that are involved in these processes function accurately. Hence, any mutation or error that occurs along the way can result in exten...... hiện toàn bộ
Formation and regulation of Yersinia biofilms
Protein & Cell - Tập 2 - Trang 173-179 - 2011
Dongsheng Zhou, Ruifu Yang
Flea-borne transmission is a recent evolutionary adaptation that distinguishes the deadly Yersinia pestis from its progenitor Y. Pseudotuberculosis, a mild pathogen transmitted via the food-borne route. Y. Pestis synthesizes biofilms in the flea gut, which is important for fleaborne transmission. Yersinia biofilms are bacterial colonies surrounded by extracellular matrix primarily containing a hom...... hiện toàn bộ
Chia Chi Wang and his research on Protozoology
Protein & Cell - Tập 13 - Trang 473-475 - 2020
Ting Shi, Lei Fu
Histone deacetylase 6 and cytoplasmic linker protein 170 function together to regulate the motility of pancreatic cancer cells
Protein & Cell - Tập 5 - Trang 214-223 - 2014
Dengwen Li, Xiaodong Sun, Linlin Zhang, Bing Yan, Songbo Xie, Ruming Liu, Min Liu, Jun Zhou
Pancreatic cancer is a devastating disease with the worst prognosis among all the major human malignancies. The propensity to rapidly metastasize contributes significantly to the highly aggressive feature of pancreatic cancer. The molecular mechanisms underlying this remain elusive, and proteins involved in the control of pancreatic cancer cell motility are not fully characterized. In this study, ...... hiện toàn bộ
TCF-1 deficiency influences the composition of intestinal microbiota and enhances susceptibility to colonic inflammation
Protein & Cell - Tập 11 - Trang 380-386 - 2020
Guotao Yu, Fang Wang, Menghao You, Tiansong Xu, Chunlei Shao, Yuning Liu, Ruiqi Liu, Min Deng, Zhihong Qi, Zhao Wang, Jingjing Liu, Yingpeng Yao, Jingjing Chen, Zhen Sun, Shanshan Hao, Wenhui Guo, Tianyan Zhao, Zhengquan Yu, Qian Zhang, Yaofeng Zhao, Feng Chen, Shuyang Yu
Phylogenetics of varied subtypes of avian influenza viruses in China: potential threat to humans
Protein & Cell - Tập 5 - Trang 253-257 - 2014
Weifeng Shi, Wei Li, Xianbin Li, Joel Haywood, Juncai Ma, George F. Gao, Di Liu
Erratum to: Questions about NgAgo
Protein & Cell - Tập 8 - Trang 77-77 - 2016
Shawn Burgess, Linzhao Cheng, Feng Gu, Junjiu Huang, Zhiwei Huang, Shuo Lin, Jinsong Li, Wei Li, Wei Qin, Yujie Sun, Zhou Songyang, Wensheng Wei, Qiang Wu, Haoyi Wang, Xiaoqun Wang, Jing-Wei Xiong, Jianzhong Xi, Hui Yang, Bin Zhou, Bo Zhang
The role of ADAMTSs in arthritis
Protein & Cell - Tập 1 - Trang 33-47 - 2010
Edward A. Lin, Chuan-Ju Liu
The ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family consists of 19 proteases. These enzymes are known to play important roles in development, angiogenesis and coagulation; dysregulation and mutation of these enzymes have been implicated in many disease processes, such as inflammation, cancer, arthritis and atherosclerosis. This review briefly summarizes the structura...... hiện toàn bộ
Naringenin giảm di căn phổi trong mô hình cắt bỏ ung thư vú Dịch bởi AI
Protein & Cell - Tập 2 - Trang 507-516 - 2011
Lei Qin, Lingtao Jin, Linlin Lu, Xiaoyan Lu, Chunling Zhang, Fayun Zhang, Wei Liang
Di căn là nguyên nhân chính gây tử vong ở bệnh nhân ung thư. Để cải thiện kết quả cho các bệnh nhân trải qua phẫu thuật, cần phát triển các liệu pháp bổ trợ mới có thể ức chế hiệu quả sự di căn. Các nghiên cứu đã chỉ ra rằng flavonoid naringenin, một sản phẩm tự nhiên chủ yếu có trong nho và các loại trái cây họ cam quýt, có thể góp phần vào việc phòng ngừa ung thư. Nó có nhiều ưu điểm so với các ...... hiện toàn bộ
#naringenin #di căn #ung thư vú #liệu pháp bổ trợ #miễn dịch
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