Pharmacotherapy
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Antiplatelet Drug Resistance: Not Ready for Prime Time
Pharmacotherapy - Tập 25 Số 11 - Trang 1621-1628 - 2005
Effect of Health Literacy on Drug Adherence in Patients with Heart Failure
Pharmacotherapy - Tập 32 Số 9 - Trang 819-826 - 2012
Study ObjectiveTo assess the effect of health literacy on drug adherence in the
context of a pharmacist‐based intervention for patients with heart
failure.DesignPost hoc analysis of a randomized controlled
trial.SettingInner‐city ambulatory care practice affiliated with an academic
medical center.PatientsThe original trial enrolled 314 patients with heart
failure who were aged 50 years or older an...
Angiotensin‐Converting Enzyme Inhibitors and Type 2 Diabetic Nephropathy: A Meta‐Analysis
Pharmacotherapy - Tập 23 Số 7 - Trang 909-915 - 2003
Objective. To perform a meta‐analysis on studies evaluating the effect of
angiotensin‐converting enzyme (ACE) inhibitors on diabetic nephropathy in
patients with type 2 diabetes mellitus.Methods. A computerized literature search
was conducted for articles of studies comparing ACE inhibitors with a control in
patients with diabetes, in which measurement of albuminuria or proteinuria was
an outcome....
Prepharmacy Predictors of Success in Pharmacy School: Grade Point Averages, Pharmacy College Admissions Test, Communication Abilities, and Critical Thinking Skills
Pharmacotherapy - Tập 21 Số 7 - Trang 842-849 - 2001
Good admissions decisions are essential for identifying successful students and
good practitioners. Various parameters have been shown to have predictive power
for academic success. Previous academic performance, the Pharmacy College
Admissions Test (PCAT), and specific prepharmacy courses have been suggested as
academic performance indicators. However, critical thinking abilities have not
been ev...
Bevacizumab Use and the Risk of Arterial and Venous Thromboembolism in Patients with High‐Grade Gliomas: A Nested Case‐Control Study
Pharmacotherapy - Tập 39 Số 9 - Trang 921-928 - 2019
Study ObjectiveBevacizumab is used in the treatment of recurrent glioblastoma,
but evidence is limited on the incidence of thromboembolic complications
regarding the use of this drug in real‐world settings. We evaluated the risk of
arterial thromboembolism (ATE) and venous thromboembolism (VTE) associated with
the use of bevacizumab among adults diagnosed with high‐grade gliomas in a
commercially ...
Treatment Guidelines for Hepatic Encephalopathy
Pharmacotherapy - Tập 30 Số 5P2 - 2010
Practice guidelines for hepatic encephalopathy were developed and published in
2001 for overall management in adults. Hepatic encephalopathy is caused by
nitrogenous substances from the gastrointestinal tract that adversely affect
brain function. Hepatic encephalopathy is a diagnosis of exclusion. The West
Haven criteria are recommended for staging the disease. Treatment goals are
providing suppor...
Safety, Efficacy, and Dosing Requirements of Bivalirudin in Patients with Heparin‐Induced Thrombocytopenia
Pharmacotherapy - Tập 28 Số 9 - Trang 1115-1124 - 2008
Study Objective. To evaluate the safety, efficacy, and dosing requirements of
bivalirudin in patients with heparin‐induced thrombocytopenia (HIT).Design.
Retrospective cohort study.Setting. University‐affiliated hospital.Patients.
Thirty‐seven adults with a diagnosis or history of HIT who were treated with
bivalirudin between January 1, 2004, and March 31, 2007.Measurements and Main
Results. Patie...
Lipid‐Lowering Efficacy, Safety, and Costs of a Large‐Scale Therapeutic Statin Formulary Conversion Program
Pharmacotherapy - Tập 21 Số 9 - Trang 1130-1139 - 2001
Study Objective. To assess the lipid‐lowering efficacy, safety, and costs of a
large‐scale statin formulary conversion program.Design. Prospective,
observational study.Setting. Tertiary academic medical center.Patients. A total
of 980 patients consented to participate; 942 patients completed the
study.Intervention. Patients were converted from their current statin therapy to
either cerivastatin 0....
Evaluation of Carvedilol for the Treatment of Portal Hypertension
Pharmacotherapy - Tập 24 Số 1 - Trang 94-104 - 2004
Development of bleeding gastroesophageal varices is a serious consequence of
portal hypertension secondary to cirrhosis. Nonselective β‐blockers have been
used to reduce portal pressures and prevent primary and secondary bleeding
episodes. However, up to two thirds of patients may not respond appropriately to
these agents. Nonselective β‐blockers combined with vasodilatory drugs result in
enhanced...
Indacaterol: A Novel Long‐Acting β2‐Agonist
Pharmacotherapy - Tập 32 Số 5 - Trang 456-474 - 2012
Bronchodilator drugs are the foundation for the treatment of chronic obstructive
pulmonary disease. The principal inhaled bronchodilator treatments used are
β2‐agonists and anticholinergics, either alone or in combination. Currently
available β2‐agonists are of either short duration and used multiple times/day,
or of long duration, which requires twice‐daily administration. Indacaterol is
consider...
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