Pharmacological Reports

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Immunosuppressants attenuate HMGB1 expression and release from primary astrocyte cultures exposed to combined oxygen-glucose deprivation
Pharmacological Reports - Tập 61 - Trang 353-353 - 2009
Bożena Gabryel, Anna Bielecka, Jacek Bernacki
Interleukin-13-induced activation of signal transducer and activator of transcription 6 is mediated by an activation of Janus kinase 1 in cultured human bronchial smooth muscle cells
Pharmacological Reports - Tập 64 - Trang 454-458 - 2012
Yoshihiko Chiba, Kumiko Goto, Miwa Misawa
The current study was carried out to identify the JAK molecule(s) that is involved in the IL-13-induced activation of STAT6 in cultured human bronchial smooth muscle cells (hBSMCs). Cultured hBSMCs were stimulated with IL-13 in the absence and presence of JAK inhibitor-I (a nonspecific JAKs inhibitor), tyrphostin-AG490 (a specific JAK2 inhibitor), WHI-P131 (a specific JAK3 inhibitor), or tyrphosti...... hiện toàn bộ
PSV-9
Pharmacological Reports - Tập 63 - Trang 257-258 - 2011
Carmen Lasheras, Ana González-Cuello, Maria Victoria Milanés, Maria Luisa Laorden
Therapeutic potential of melatonin in targeting molecular pathways of organ fibrosis
Pharmacological Reports - - 2024
Azam Hosseinzadeh, Mohammad Hossein Pourhanifeh, Shiva Amiri, Mohammad Sheibani, Rana Irilouzadian, Russel J. Reíter, Saeed Mehrzadi
Pioglitazone, an anti-diabetic drug requires sustained MAPK activation for its anti-tumor activity in MCF7 breast cancer cells, independent of PPAR-γ pathway
Pharmacological Reports - Tập 68 - Trang 144-154 - 2016
Labanyamoy Kole, Mrinmoy Sarkar, Anwesha Deb, Biplab Giri
Chemosensitive effects of Astragaloside IV in osteosarcoma cells via induction of apoptosis and regulation of caspase-dependent Fas/FasL signaling
Pharmacological Reports - Tập 69 - Trang 1159-1164 - 2017
Tongzhou Hu, Zhenghua Fei, Nan Wei
The response of conventional chemotherapy for osteosarcoma treatment is usually poor, and chemotherapy-related severe side effects and drug resistance remain a problem. Abundant evidence has shown that Astragaloside IV, extracted from Astragalus membranaceus Bunge, strongly inhibits the growth of many carcinomas. We aimed to investigate the chemosensitive effects of Astragaloside IV in osteosarcom...... hiện toàn bộ
Flowers for Algernon: steroid dysgenesis, epigenetics and brain disorders
Pharmacological Reports - Tập 64 Số 6 - Trang 1285-1290 - 2012
Bryan K. Sanders
7-Arylpiperazinylalkyl derivatives of purine-2,6-dione in functional and behavioral experiments
Pharmacological Reports - Tập 65 - Trang 129-130 - 2013
Anna Partyka, Dagmara Wróbel, Anna Wasik, Magdalena Jastrzębska-Więsek, Grażyna Chłoń, Grzegorz Satała, Andrzej J. Bojarski, Anna Wesołowska
Teratogenic potential of third-generation antiepileptic drugs: Current status and research needs
Pharmacological Reports - Tập 71 Số 3 - Trang 491-502 - 2019
K. P. Singh, Niharika Verma
Blockade of fructose transporter protein GLUT5 inhibits proliferation of colon cancer cells: proof of concept for a new class of anti-tumor therapeutics
Pharmacological Reports - Tập 73 - Trang 939-945 - 2021
Jakub Włodarczyk, Marcin Włodarczyk, Marta Zielińska, Bartłomiej Jędrzejczak, Łukasz Dziki, Jakub Fichna
Despite the fact that colorectal cancer (CRC) is one of the most commonly diagnosed cancers in men and women, its current treatment remains unsatisfactory and therefore novel studies proposing new approaches are necessary. A high sugar diet is believed to promote carcinogenesis. Fructose is absorbed from the gastrointestinal tract by members of the glucose transporter family—GLUT. The aim of the s...... hiện toàn bộ
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