Pharmacological Reports
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The influence of the acute and chronic administration of LPS on α-synuclein expression in rat brains
Pharmacological Reports - Tập 61 - Trang 357-358 - 2009
Effect of p-isopropoxyphenylsuccinimide monohydrate on the anticonvulsant action of carbamazepine, phenobarbital, phenytoin and valproate in the mouse maximal electroshock-induced seizure model
Pharmacological Reports - Tập 62 Số 1 - Trang 194-202 - 2010
Important role of 3-methoxytyramine in the inhibition of cocaine sensitization by 1-methyl-1,2,3,4-tetrahydroisoquinoline: an in vivo microdialysis study
Pharmacological Reports - Tập 62 - Trang 983-997 - 2010
1-Methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ) is an endogenous compound with neuroprotective and antidopaminergic activities. Our previous research has shown that 1MeTIQ prevents morphine addiction and abates the expression of the reinstatement of cocaine self-administration. The current study investigated the mechanism of action of 1MeTIQ that is responsible for its considerable anticraving po...... hiện toàn bộ
Intranasal ondansetron microemulsion counteracting the adverse effects of cisplatin: animal study
Pharmacological Reports - Tập 75 - Trang 199-210 - 2022
Cisplatin is considered one of the most effective and commonly used chemotherapeutic drugs, but despite its high therapeutic effectiveness, most patients treated with cisplatin suffer from nausea and vomiting, neurotoxic side effects, and cerebral psychiatric disorders such as depression. Therefore, the aim of the current work was to explore whether a selective 5-HT3 receptor antagonist (Ondansetr...... hiện toàn bộ
Effects and mechanisms of phthalates’ action on neurological processes and neural health: a literature review
Pharmacological Reports - Tập 73 - Trang 386-404 - 2021
During the period of mass industrial production of plastic products, the quality of human health has decreased significantly, especially in children’s neurodevelopmental disorders. Phthalates are endocrine-disrupting chemicals that can induce neurological disorders. This review aims to compile evidence concerning the associations between neurological disorders, such as attention-deficit/hyperactiv...... hiện toàn bộ
Role of Ca2+ imbalance mediated by NMDA and ryanodine receptors in acute TBBPA toxicity in primary cultures of rat cerebellar granule cells
Pharmacological Reports - Tập 65 Số 1 - Trang 105-106 - 2013
Three neurosteroids as well as GABAergic drugs do not convert immediate postictal potentiation to depression in immature rats
Pharmacological Reports - Tập 72 - Trang 1573-1578 - 2020
Postictal potentiation presented immediately after cortical seizures in immature rats might be due to imbalance between excitation and inhibition. The aim of the present study was to determine whether augmentation of inhibition mediated by GABAA receptors could also suppress the postictal potentiation. Twelve-day old rats with implanted electrodes were used in our study. Five drugs were tested: th...... hiện toàn bộ
The effects of vasoactive peptide urocortin 2 on hemodynamics in spontaneous hypertensive rat and the role of L-type calcium channel and CRFR2
Pharmacological Reports - Tập 67 - Trang 394-398 - 2015
Antidepressant-like effects of cannabidiol in a rat model of early-life stress with or without adolescent cocaine exposure
Pharmacological Reports - Tập 73 - Trang 1195-1202 - 2021
Further studies are needed to better understand the effects of potential novel antidepressants, such as cannabidiol, for the treatment of psychiatric disorders during adolescence. In this context, we evaluated in a rodent model of early-life stress (a single 24-h episode of maternal deprivation, PND 9), the antidepressant-like effects of adolescent cannabidiol alone and/or in combination with adol...... hiện toàn bộ
Anticonvulsant effects of combinations among three antiepileptic drugs — an isobolographic analysis
Pharmacological Reports - Tập 64 - Trang 237-239 - 2012
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