Can We Accurately Predict Cost Effectiveness Without Access to Overall Survival Data? The Case Study of Nivolumab in Combination with Ipilimumab for the Treatment of Patients with Advanced Melanoma in EnglandPharmacoEconomics - Open - Tập 3 - Trang 43-54 - 2018
D. Lee, A. Amadi, J. Sabater, J. Ellis, H. Johnson, S. Kotapati, S. McNamara, A. Walker, M. Cooper, K. Patterson, N. Roskell, Y. Meng
Nivolumab with ipilimumab (the Regimen) is the first immuno-oncology combination treatment to demonstrate long-term clinical benefit for advanced melanoma patients. We evaluated the cost effectiveness of the Regimen in this population, with and without the availability of overall survival (OS) data. A partitioned survival model and a Markov state-transition model were developed to estimate the lif...... hiện toàn bộ
Economic Evaluation of Using Daily Prednisolone versus Placebo at the Time of an Upper Respiratory Tract Infection for the Management of Children with Steroid-Sensitive Nephrotic Syndrome: A Model-Based AnalysisPharmacoEconomics - Open - Tập 6 - Trang 605-617 - 2022
Nafsika Afentou, Emma Frew, Samir Mehta, Natalie J. Ives, Rebecca L. Woolley, Elizabeth A. Brettell, Adam R. Khan, David V. Milford, Detlef Bockenhauer, Moin A. Saleem, Angela S. Hall, Ania Koziell, Heather Maxwell, Shivaram Hegde, Eric Finlay, Rodney D. Gilbert, Caroline Jones, Karl McKeever, Wendy Cook, Nicholas J. A. Webb, Martin T. Christian
Childhood steroid-sensitive nephrotic syndrome is a frequently relapsing disease with significant short- and long-term complications, leading to high healthcare costs and reduced quality of life for patients. The majority of relapses are triggered by upper respiratory tract infections (URTIs) and evidence shows that daily low-dose prednisolone at the time of infection may reduce the risk of relaps...... hiện toàn bộ
Identification and prioritisation of items for a draft participant-reported questionnaire to measure use of social care, informal care, aids and adaptationsPharmacoEconomics - Open - - 2024
Kirsty M. Garfield, Gail A. Thornton, Samantha Husbands, Ailsa Cameron, William Hollingworth, Sian M. Noble, Paul Roy, Joanna C. Thorn
Resource-use measurement is integral for assessing cost-effectiveness within trial-based economic evaluations. Methods for gathering resource-use data from participants are not well developed, with questionnaires typically produced for each trial and rarely validated. The healthcare module of a generic, modular resource-use measure, designed for collecting self-report resource-utilisation data, ha...... hiện toàn bộ