Pharmaceutical Medicine
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Integrating Genomics into Drug Discovery and Development: Challenges and Aspirations
Pharmaceutical Medicine - Tập 31 - Trang 217-233 - 2017
Molecular biomarkers are increasingly being used to identify subgroups of patients that have a higher chance of benefiting from targeted therapies. Identification of predictive biomarkers and development of companion diagnostics to accompany targeted agents have been shown to significantly improve the efficacy and approval rate of these novel therapies, making treatment decisions more personalized......
Clinical Trials in Children
Pharmaceutical Medicine - Tập 21 - Trang 121-129 - 2012
Ethical concerns and paediatric clinical trials go hand in hand. Without knowledge on how to overcome ethical challenges, companies will struggle to develop drugs for the paediatric population. This article reviews the ethical hurdles of paediatric research and offers some strategies to overcome these challenges. It also describes the basic principles of medical ethics, discusses ethical issues un......
Assessing the Value of System Theoretic Process Analysis in a Pharmacovigilance Process: An Example Using Signal Management
Pharmaceutical Medicine - - 2017
A Principles Framework for Digital Provision of Medical Information for Healthcare Professionals
Pharmaceutical Medicine - Tập 37 - Trang 103-109 - 2023
European pharmaceutical companies have a legal requirement to provide non-promotional medical information (MI) services to support healthcare professionals (HCPs) using their medicinal products. While we are seeing an increased HCP preference and expectation towards digital channels, the lack of a compliance framework relating to the provision of non-promotional MI services is a key factor complic......
Report on Drug Safety and the US FDA by the Institute of Medicine
Pharmaceutical Medicine - Tập 20 - Trang 289-291 - 2012
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