Planar Cell Polarity Signaling in Mammalian Cardiac MorphogenesisPediatric Cardiology - Tập 39 - Trang 1052-1062 - 2018
Ding Li, Jianbo Wang
The mammalian heart is the first organ to form and is critical for embryonic survival and development. With an occurrence of 1%, congenital heart defects (CHDs) are also the most common birth defects in humans, and major cause of childhood morbidity and mortality (Hoffman and Kaplan in J Am Coll Cardiol 39(12):1890–1900, 2002; Samanek in Cardiol Young 10(3):179–185, 2000). Understanding how the he...... hiện toàn bộ
Effective Radiation Dose in Computed Tomographic Angiography of the Chest and Diagnostic Cardiac Catheterization in Pediatric PatientsPediatric Cardiology - Tập 34 - Trang 518-524 - 2012
Timotheus G. Watson, Eugene Mah, U. Joseph Schoepf, Lydia King, Walter Huda, Anthony M. Hlavacek
Computed tomographic angiography (CTA) and cardiac catheterization are useful adjuncts to echocardiography for delineating cardiovascular anatomy in pediatric patients. These studies require ionizing radiation, and it is paramount to understand the amount of radiation pediatric patients receive when these tests are performed. Modern dosimetry methods facilitate the conversion of radiation doses of...... hiện toàn bộ
Safety of Magnetic Resonance Imaging After Implantation of Stainless Steel Embolization CoilsPediatric Cardiology - Tập 37 - Trang 62-67 - 2015
Timothy C. Slesnick, Jenna Schreier, Brian D. Soriano, Shelby Kutty, Arni C. Nutting, Dennis W. Kim, Andrew J. Powell, Anne Marie Valente
Stainless steel embolization coils (SSEC) have been used for over four decades for vascular occlusion. Recently, the safety of these coils in a magnetic resonance environment has been called into question, with important ramifications for thousands of patients with existing coils in place. We performed a retrospective chart review at five tertiary care pediatric centers evaluating all children and...... hiện toàn bộ
Partially Penetrant Cardiac Neural Crest Defects in Hand1 Phosphomutant Mice: Dimer Choice That Is Not So CriticalPediatric Cardiology - Tập 40 - Trang 1339-1344 - 2019
Beth A. Firulli, Anthony B. Firulli
Hand1 is a basic Helix–loop–Helix transcription factor that exhibits post-translationally regulated dimer partner choice that allows for a diverse set of Hand1 transcriptional complexes. Indeed, when Hand1 phosphoregulation is altered, conditionally activated hypophorylation (Hand1PO4−) and phosphorylation mimic (Hand1PO4+) Hand1 alleles disrupt both craniofacial and limb morphogenesis with 100% p...... hiện toàn bộ
Cardiac Function After Repair of Tetralogy of Fallot: How are the Atria Performing? Pilot Study by Cardiac Magnetic Resonance ImagingPediatric Cardiology - Tập 36 - Trang 96-105 - 2014
C. Wohlmuth, C. J. Kellenberger, E. M. Voser, B. E. Burkhardt, E. R. Valsangiacomo Buechel
The atria of the heart function as reservoir, conduit, and active pump and are critical for ventricular filling and cardiac output. We sought to evaluate right (RA) and left atrial (LA) function in patients after tetralogy of Fallot (TOF) repair by using cardiovascular magnetic resonance. Twelve TOF patients, age 16.7 ± 6.1 years, weight 50.9 ± 14.9 kg, were compared to 10 healthy volunteers, age ...... hiện toàn bộ
Apical Hypertrophic Cardiomyopathy in Childhood: A Long-Term Follow-Up Report of Two CasesPediatric Cardiology - Tập 30 - Trang 343-346 - 2008
Tomoyuki Miyamoto, Hitoshi Horigome, Satoru Kawano, Ryo Sumazaki
We present two children with apical hypertrophic cardiomyopathy (APH), both of whom remained asymptomatic for more than 15 years. The inverted T-wave on electrocardiograms and myocardial hypertrophy mostly confined to the apical region on echocardiograms showed no significant changes during follow-up. Magnetic resonance imaging revealed a cavitylike portion at the apex in one case, but the diagnos...... hiện toàn bộ
Myocardial Contractility in Premature Neonates With and Without Patent Ductus ArteriosusPediatric Cardiology - Tập 25 - Trang 102-107 - 2003
A. J. Barlow, C. Ward, S. A. Webber, B. G. Sinclair, J.E. Potts, G.G.S. Sandor
Controversy exists as to whether a hemodynamically significant left-to-right shunt due to a patent ductus arteriosus (PDA) affects ventricular contractility. Load-dependent indices such as ejection fraction and shortening fraction have traditionally been used to assess contractility, but the relationship between the rate-corrected velocity of fiber shortening (MVCFc) and wall stress may be more su...... hiện toàn bộ