Pediatric Cardiology
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Planar Cell Polarity Signaling in Mammalian Cardiac Morphogenesis
Pediatric Cardiology - Tập 39 - Trang 1052-1062 - 2018
The mammalian heart is the first organ to form and is critical for embryonic survival and development. With an occurrence of 1%, congenital heart defects (CHDs) are also the most common birth defects in humans, and major cause of childhood morbidity and mortality (Hoffman and Kaplan in J Am Coll Cardiol 39(12):1890–1900, 2002; Samanek in Cardiol Young 10(3):179–185, 2000). Understanding how the he......
Pulmonary atresia with intact ventricular septum: A quantitative cineventriculographic study of the right and left ventricular function
Pediatric Cardiology - - 1986
Safety of Magnetic Resonance Imaging After Implantation of Stainless Steel Embolization Coils
Pediatric Cardiology - Tập 37 - Trang 62-67 - 2015
Stainless steel embolization coils (SSEC) have been used for over four decades for vascular occlusion. Recently, the safety of these coils in a magnetic resonance environment has been called into question, with important ramifications for thousands of patients with existing coils in place. We performed a retrospective chart review at five tertiary care pediatric centers evaluating all children and......
Partially Penetrant Cardiac Neural Crest Defects in Hand1 Phosphomutant Mice: Dimer Choice That Is Not So Critical
Pediatric Cardiology - Tập 40 - Trang 1339-1344 - 2019
Hand1 is a basic Helix–loop–Helix transcription factor that exhibits post-translationally regulated dimer partner choice that allows for a diverse set of Hand1 transcriptional complexes. Indeed, when Hand1 phosphoregulation is altered, conditionally activated hypophorylation (Hand1PO4−) and phosphorylation mimic (Hand1PO4+) Hand1 alleles disrupt both craniofacial and limb morphogenesis with 100% p......
Radiation Dose Reduction in Pediatric Cardiac Computed Tomography: Experience from a Tertiary Medical Center
Pediatric Cardiology - - 2014
Cardiac Function After Repair of Tetralogy of Fallot: How are the Atria Performing? Pilot Study by Cardiac Magnetic Resonance Imaging
Pediatric Cardiology - Tập 36 - Trang 96-105 - 2014
The atria of the heart function as reservoir, conduit, and active pump and are critical for ventricular filling and cardiac output. We sought to evaluate right (RA) and left atrial (LA) function in patients after tetralogy of Fallot (TOF) repair by using cardiovascular magnetic resonance. Twelve TOF patients, age 16.7 ± 6.1 years, weight 50.9 ± 14.9 kg, were compared to 10 healthy volunteers, age ......
Failure of adenosine to terminate focal atrial tachycardia
Pediatric Cardiology - Tập 14 - Trang 119-121 - 1993
Adenosine has proven effectiveness in the diagnosis and treatment of a variety of tachycardias with both normal and widened QRS complexes in children and adults. Its effectiveness is due to its depressant effects on atrioventricular node conduction. Adenosine might also be effective against automatic tachycardia due to spontaneous activation in partially depolarized cells. This report describes a ......
Calf Muscle Oxygenation is Impaired and May Decline with Age in Young Patients with Total Cavopulmonary Connection
Pediatric Cardiology - Tập 43 - Trang 449-456 - 2021
Patients palliated with Total Cavopulmonary Connection have a lower muscle mass and a lower exercise capacity. We assessed calf muscle oxidative metabolism during and after heel raise exercise to exhaustion in young patients with TCPC compared to healthy peers. Near-infrared spectroscopy was used for measuring oxygen metabolism in the medial portion of the gastrocnemius muscle. Forty-three patient......
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