Hormonal Predictors of Bone Loss in Elderly Women: A Prospective StudyOxford University Press (OUP) - Tập 13 Số 7 - Trang 1167-1174 - 1998
Katie Stone, Douglas C. Bauer, Dennis M. Black, Peter M. Sklarin, Kristine E. Ensrud, S. R. Cummings
Abstract
To test the hypotheses that baseline concentrations of sex steroids, sex hormone binding globulin (SHBG), and calciotropic hormones predict rates of bone loss in elderly women, sera were stored at −190°C, and calcaneal bone mineral density (BMD) was measured in 9704 community-dwelling white women aged 65 and over (1986–1988). Hip BMD was mea...... hiện toàn bộ
Biochemical Markers of Bone Turnover and Prediction of Hip Bone Loss in Older Women: The Study of Osteoporotic FracturesOxford University Press (OUP) - Tập 14 Số 8 - Trang 1404-1410 - 1999
Douglas C. Bauer, Peter M. Sklarin, Katie Stone, Dennis M. Black, Michael C. Nevitt, Kristine E. Ensrud, Claude D. Arnaud, Harry K. Genant, Patrick Garnero, P. D. Delmas, Henrik Lawaetz, S. R. Cummings
Abstract
To examine the ability of commercially available biochemical markers of bone formation and resorption to predict hip bone loss, we prospectively obtained serum and timed 2-h urine specimens from 295 women age 67 years or older who were not receiving estrogen replacement therapy. Serum was assayed for two markers of bone formation: osteocalci...... hiện toàn bộ
The Roles of Osteoprotegerin and Osteoprotegerin Ligand in the Paracrine Regulation of Bone ResorptionOxford University Press (OUP) - Tập 15 Số 1 - Trang 2-12 - 2000
Lorenz C. Hofbauer, Sundeep Khosla, Colin R. Dunstan, David L. Lacey, William J. Boyle, B. Lawrence Riggs
Abstract
Although multiple hormones and cytokines regulate various aspects of osteoclast formation, the final two effectors are osteoprotegerin ligand (OPG-L)/osteoclast differentiation factor (ODF), a recently cloned member of the tumor necrosis factor superfamily, and macrophage colony–stimulating factor. OPG-L/ODF is produced by osteoblast lineage...... hiện toàn bộ
Serum Estradiol and Sex Hormone-Binding Globulin and the Risk of Hip Fracture in Elderly Women: The EPIDOS StudyOxford University Press (OUP) - Tập 15 Số 9 - Trang 1835-1841 - 2000
Roland Chapurlat, Patrick Garnero, Gérard Bréart, Pierre J. Meunier, Pierre D. Delmas
Abstract
It has been suggested that low serum 17β-estradiol (E2) and sex hormone-binding globulin (SHBG) may predict hip fracture in postmenopausal women. We have investigated the predictive value of serum E2 and SHBG concentrations and urinary deoxypyridinoline (D-Pyr) and type I collagen breakdown products (CTX) in a large prospective cohort of 759...... hiện toàn bộ
Static and tetracycline-based bone histomorphometric data from 34 normal postmenopausal femalesOxford University Press (OUP) - Tập 3 Số 2 - Trang 133-144 - 1988
Robert R. Recker, Donald B. Kimmel, Michael A. Parfitt, Michael K. Davies, N.M. Keshawarz, Sharilyn M. Hinders
Abstract
Transilial bone biopsies were obtained from 34 healthy postmenopausal women following in vivo fluorochrome labeling. Stained and unstained undecalcified sections were evaluated using a Merz grid. Standard histomorphometric data from cancellous bone tissue were collected and the results were evaluated and presented as variables commonly used ...... hiện toàn bộ
Tỷ Lệ Xuất Hiện và Gánh Nặng Kinh Tế của Các Chấn Thương Liên Quan Đến Loãng Xương Tại Hoa Kỳ, 2005–2025 Dịch bởi AI Oxford University Press (OUP) - Tập 22 Số 3 - Trang 465-475 - 2007
Russel Burge, Bess Dawson‐Hughes, Daniel H. Solomon, John B. Wong, Alison B. King, Anna N.A. Tosteson
Tóm tắt
Nghiên cứu này dự đoán gánh nặng của các chấn thương liên quan đến loãng xương và chi phí tại Hoa Kỳ, phân theo giới tính, nhóm tuổi, chủng tộc/dân tộc và loại chấn thương, từ năm 2005 đến 2025. Tổng số chấn thương vượt quá 2 triệu, với chi phí gần 17 tỷ USD vào năm 2005. Nam giới chiếm hơn 25% gánh nặng. Sự gia tăng nhanh chóng trong gánh nặ...... hiện toàn bộ
Growing C57Bl/6 Mice Increase Whole Bone Mechanical Properties by Increasing Geometric and Material PropertiesOxford University Press (OUP) - Tập 14 Số 12 - Trang 2159-2166 - 1999
Michael D. Brodt, Cara B. Ellis, Matthew J. Silva
Abstract
In vivo murine models are becoming increasingly important in bone research. To establish baseline data for researchers using these models, we studied the long bones from C57BL/6 female mice, a strain that is widely used in bone research. We determined the femoral structural and material properties in both torsion and four-point bending for m...... hiện toàn bộ
Enhanced Expression of the Inorganic Phosphate Transporter Pit-1 Is Involved in BMP-2–Induced Matrix Mineralization in Osteoblast-Like CellsOxford University Press (OUP) - Tập 21 Số 5 - Trang 674-683 - 2006
Atsushi Suzuki, Chafik Ghayor, Jérôme Guicheux, David Magne, S. Quillard, Ayako Kakita, Yuka Ono, Yoshitaka Miura, Yutaka Oiso, Mitsuyasu Itoh, Joseph Caverzasio
Abstract
Pi handling by osteogenic cells is important for bone mineralization. The role of Pi transport in BMP-2–induced matrix calcification was studied. BMP-2 enhances Pit-1 Pi transporters in osteogenic cells. Experimental analysis suggest that this response is required for bone matrix calcification.
Introduction: B...... hiện toàn bộ