In rheumatoid arthritis patients treated with tocilizumab, the rate of clinical disease activity index (CDAI) remission at 24 weeks is superior in those with higher titers of IgM-rheumatoid factor at baselineOxford University Press (OUP) - - 2011
Shin‐ya Kawashiri, Atsushi Kawakami, Naoki Iwamoto, Keita Fujikawa, Toshiyuki Aramaki, Mami Tamai, Satoshi Yamasaki, Hideki Nakamura, Tomoki Origuchi, Yukitaka Ueki, Kiyoshi Migita, Akiko Mizokami, Kiyoshi Aoyagi, Katsumi Eguchi
Locking of the knee caused by localized pigmented villonodular synovitis: a case reportOxford University Press (OUP) - Tập 14 Số 2 - Trang 184-186 - 2004
Horiuchi, Hiroshi, Nawata, Masashi, Kamijo, Tetsuyoshi, Saito, Naoto, Wakitani, Shigeyuki, Kobayashi, Seneki, Shimizu, Tominaga, Kato, Hiroyuki
Pigmented villonodullar synovitis (PVS) occurs in two forms: diffuse PVS and localized pigmented villonodular synovitis. In this report, a 40-year-old woman presented with a history of recurrent episodes of knee locking and pain. Arthroscopy revealed a nodular pedunculated mass occupying the area anterior to the intercondylar notch of the femur. Histological examination of the tissue confirmed the...... hiện toàn bộ
Therapeutic response of patients with adult Still’s disease to biologic agents: multicenter results in JapanOxford University Press (OUP) - Tập 22 - Trang 712-719 - 2011
Rie Suematsu, Akihide Ohta, Emi Matsuura, Hiroki Takahashi, Takao Fujii, Takahiko Horiuchi, Seiji Minota, Yoshiaki Ishigatsubo, Toshiyuki Ota, Shuji Takei, Sachiko Soejima, Hisako Inoue, Syuichi Koarada, Yoshifumi Tada, Kohei Nagasawa
The efficacy of biologics in treating adult Still’s disease (ASD) is suggested, but the information is still lacking and the validation is insufficient. To determine the efficacy of several biologic agents in refractory ASD in Japan, a multicenter survey was performed. Clinical data on 16 ASD patients who had been treated with at least 1 of the biological agents (total 24 occasions) were collected...... hiện toàn bộ
Drug free REmission/low disease activity after cessation of tocilizumab (Actemra) Monotherapy (DREAM) studyOxford University Press (OUP) - - Trang 1-9 - 2013
Norihiro Nishimoto, Koichi Amano, Yasuhiko Hirabayashi, Takahiko Horiuchi, Tomonori Ishii, Mitsuhiro Iwahashi, Masahiro Iwamoto, Hitoshi Kohsaka, Masakazu Kondo, Tsukasa Matsubara, Toshihide Mimura, Hisaaki Miyahara, Shuji Ohta, Yukihiko Saeki, Kazuyoshi Saito, Hajime Sano, Kiyoshi Takasugi, Tsutomu Takeuchi, Shigeto Tohma, Tomomi Tsuru, Yukitaka Ueki, Jiro Yamana, Jun Hashimoto, Takaji Matsutani, Miho Murakami, Nobuhiro Takagi
To investigate the duration of remission and low disease activity (LDA) after cessation of tocilizumab (TCZ) treatment in rheumatoid arthritis patients who showed remission or LDA as assessed by DAS28 in response to preceding TCZ monotherapy, and to explore the factors contributing to prolonged efficacy duration. Disease activity was monitored for 56 weeks. The rate of continued efficacy was estim...... hiện toàn bộ
A case of Mikulicz’s disease with Th2-biased cytokine profile: possible feature discriminable from Sjögren’s syndromeOxford University Press (OUP) - Tập 19 - Trang 691-695 - 2009
Eriko Kudo-Tanaka, Shinichi Nakatsuka, Toru Hirano, Mari Kawai, Yoshinori Katada, Masato Matsushita, Shiro Ohshima, Masaru Ishii, Kunio Miyatake, Toshio Tanaka, Yukihiko Saeki
This article concerns a male patient with Mikulicz’s disease (MD) accompanied with marked elevation of serum immunoglobulin (Ig)G4 and IgE levels. His peripheral blood mononuclear cells (PBMC) showed markedly enhanced in vitro production of interleukin (IL)-4, IL-5, IL-13, but not interferon gamma (IFN-γ) compared with patients with Sjögren’s syndrome (SS) and healthy donors, suggesting distinct T...... hiện toàn bộ
Total knee arthroplasty for rheumatoid arthritisOxford University Press (OUP) - Tập 13 - Trang 289-292 - 2003
Paul J. Kerner, Henry D. Clarke, Giles R. Scuderi
Total knee arthroplasty is a proven technique for the management of deformity and unremitting pain in the rheumatoid arthritic knee. Many important considerations must be taken into account in order to maximize the results of total knee replacement in this challenging patient population.
QT dispersion and transmural dispersion of repolarization in patients with familial Mediterranean feverOxford University Press (OUP) - Tập 19 - Trang 550-555 - 2009
Ahmet Akcay, Gurkan Acar, Mehmet Sayarlioglu, Abdullah Sokmen, Hakan Kaya, Murat Ispiroglu, Sedat Koroglu
Familial Mediterranean fever (FMF) is a disease characterized by sporadic, paroxysmal attacks of fever and serosal inflammation. QT dispersion (QTd) and transmural dispersion of repolarization (TDR), simple noninvasive arrhythmogenic markers, that can be used to assess homogeneity of cardiac repolarization, have not been studied in FMF patients before. The aim of our study was to evaluate the QTd ...... hiện toàn bộ