Ovid Technologies (Wolters Kluwer Health)

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Inhibition of exercise-induced shortening of bleeding time by fish oil in familial hypercholesterolemia (type IIa).
Ovid Technologies (Wolters Kluwer Health) - Tập 13 Số 1 - Trang 98-104 - 1993
J.B. Hansen, V Lyngmo, Birgit Svensson, Arne Nordøy
Fourteen patients suffering from familial hypercholesterolemia (type IIa) participated in a double-blind, placebo-controlled trial that evaluated the effects of fish oil ethyl ester (K-85, 5.7 g/day) or a hydroxymethylglutaryl coenzyme A reductase inhibitor (lovastatin, 40 mg/day) alone or in combination on lipid metabolism and bleeding time at rest and after standardized exercise. Lovastatin trea... hiện toàn bộ
Relations of plasma TG and HDL-C concentrations to body composition and plasma insulin levels are altered in men with small LDL particles.
Ovid Technologies (Wolters Kluwer Health) - Tập 14 Số 7 - Trang 1121-1128 - 1994
Leslie I. Katzel, Ronald M. Krauss, Andrew P. Goldberg
Low-density lipoprotein (LDL) subclass pattern B is characterized by a predominance of small, dense LDL particles (LDL peak particle size < or = 255 A), increased plasma triglyceride (TG) levels, reduced high-density lipoprotein (HDL) cholesterol levels, and glucose intolerance. This study tested the hypothesis that there are differences in the regulation of TG and HDL metabolism by insulin in pat... hiện toàn bộ
Change in LDL particle size is associated with change in plasma triglyceride concentration.
Ovid Technologies (Wolters Kluwer Health) - Tập 12 Số 11 - Trang 1284-1290 - 1992
Judith McNamara, J L Jenner, Z Li, P W Wilson, Ernst J. Schaefer
Low density lipoprotein (LDL) particle size is inversely associated with plasma triglyceride concentration in cross-sectional analyses. In the present study, changes in the LDL particle size of 227 participants of the Framingham Offspring Study were analyzed longitudinally by nondenaturing gradient gel electrophoresis at two examinations that were separated by 3-4 years. All subjects had triglycer... hiện toàn bộ
Influence of plasma cholesteryl ester transfer activity on the LDL and HDL distribution profiles in normolipidemic subjects.
Ovid Technologies (Wolters Kluwer Health) - Tập 13 Số 6 - Trang 815-825 - 1993
Laurent Lagrost, Hassan Gandjini, Anne Athias, Valérie Guyard‐Dangremont, Christian Lallemant, Philippe Gambert
The relations of cholesteryl ester transfer protein (CETP) activity to the distribution of low density lipoproteins (LDLs) and high density lipoproteins (HDLs) were investigated in fasting plasma samples from 27 normolipidemic subjects. LDL and HDL subfractions were separated by electrophoresis on 20-160 g/L and 40-300 g/L polyacrylamide gradient gels, respectively. Subjects were subdivided into t... hiện toàn bộ
Effect of hepatic lipase on LDL in normal men and those with coronary artery disease.
Ovid Technologies (Wolters Kluwer Health) - Tập 13 Số 2 - Trang 147-153 - 1993
Alberto Zambon, Melissa A. Austin, B. Greg Brown, John E. Hokanson, John D. Brunzell
Hepatic triglyceride lipase (HL) is thought to play a role in the formation of low density lipoproteins (LDLs) from small very low density lipoproteins (VLDLs) and intermediate density lipoproteins (IDLs). To analyze the possible physiological role of HL in determining LDL buoyancy, size, and chemical composition, HL activity and LDL were studied in 21 patients with coronary artery disease (CAD) a... hiện toàn bộ
LDL subclass phenotypes and triglyceride metabolism in non-insulin-dependent diabetes.
Ovid Technologies (Wolters Kluwer Health) - Tập 12 Số 12 - Trang 1496-1502 - 1992
Kenneth R. Feingold, Carl Grünfeld, M Pang, William T. Doerrler, Ronald M. Krauss
Plasma low density lipoprotein (LDL) comprises multiple discrete subclasses differing in size, density, and chemical composition. A common, heritable phenotype characterized by the predominance of small, dense LDL particles (LDL subclass phenotype B) is associated with relatively increased concentrations of plasma triglycerides, reduced levels of high density lipoprotein, and increased risk of cor... hiện toàn bộ
The PLAT Study: hemostatic function in relation to atherothrombotic ischemic events in vascular disease patients. Principal results. PLAT Study Group. Progetto Lombardo Atero-Trombosi (PLAT) Study Group.
Ovid Technologies (Wolters Kluwer Health) - Tập 12 Số 9 - Trang 1063-1070 - 1992
M Cortellaro, Carla Boschetti, E Cofrancesco, C Zanussi, M. Catalano, Giovanni de Gaetano, L. Gabrielli, B Lombardi, Giorgina Specchia, Luigi Tavazzi
The Progetto Lombardo Atero-Trombosi (PLAT) Study was a prospective, multicenter, multidisciplinary study of the association among hemostatic variables, conventional risk factors, and atherothrombotic events in four groups of patients with preexisting vascular ischemic disease (335 myocardial infarction survivors, 123 patients with stable angina pectoris, 160 with transient ischemic attacks, and 3... hiện toàn bộ
Association of hemostatic variables with prevalent cardiovascular disease and asymptomatic carotid artery atherosclerosis. The Atherosclerosis Risk in Communities (ARIC) Study Investigators.
Ovid Technologies (Wolters Kluwer Health) - Tập 13 Số 12 - Trang 1829-1836 - 1993
Aaron R. Folsom, K K Wu, Eyal Shahar, C E Davis
The relation of hemostatic factor levels to the occurrence of cardiovascular disease is incompletely established. The Atherosclerosis Risk in Communities Study measured fibrinogen, factor VII, factor VIII, von Willebrand factor, antithrombin III, protein C, activated partial thromboplastin time, and other cardiovascular risk factors in nearly 15,000 men and women aged 45 to 64. This analysis asses... hiện toàn bộ
Hyperinsulinemia, risk factors, and coronary heart disease. The Zutphen Elderly Study.
Ovid Technologies (Wolters Kluwer Health) - Tập 14 Số 10 - Trang 1641-1647 - 1994
Edith J. M. Feskens, TH Lam
We investigated the association between fasting insulin concentration--an indicator of insulin resistance in nondiabetic individuals--cardiovascular risk factors, and coronary heart disease in a study of 390 men in the town of Zutphen. In 1990, an extensive examination was carried out on the participating men (aged 70 to 89 years). Fasting insulin levels were determined and a number of other risk ... hiện toàn bộ
Probucol treatment affects the cellular composition but not anti-oxidized low density lipoprotein immunoreactivity of plaques from Watanabe heritable hyperlipidemic rabbits.
Ovid Technologies (Wolters Kluwer Health) - Tập 11 Số 3 - Trang 751-759 - 1991
Kevin D. O’Brien, Yutaka Nagano, A M Gown, Toshiyuki Kita, Alan Chait
Use of the antioxidant probucol has been associated with a reduction in the development of atherosclerotic lesions in Watanabe heritable hyperlipidemic (WHHL) rabbits, an animal model of familial hypercholesterolemia. In this study, atheromatous lesions from control or probucol-treated WHHL rabbits were probed with monoclonal antibodies to evaluate whether use of this drug either affected the pres... hiện toàn bộ
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