Question 8: Bridging the Gap Between In Silico and In Vitro Approaches to Minimal CellsOrigins of life - Tập 37 - Trang 455-458 - 2007
Fabio Mavelli, Kepa Ruiz-Mirazo
In this short paper we argue for the relevance and value of theoretical models
in the field of origins of life, but also claim that both theoreticians and
experimentalists should make an effort to come together and interact more
closely to obtain more fruitful and significant results. As an example, we
present our own modeling approach to protocell dynamics, including some
simulation results, to s... hiện toàn bộ
Life on Jupiter?Origins of life - Tập 5 Số 3-4 - Trang 483-486 - 1974
W. F. Libby
Attempted asymmetric electrochemical reductions in magnetic fieldsOrigins of life - Tập 20 - Trang 1-13 - 1990
William A. Bonner
Because of negative, ambiguous or controversial results claimed by previous
investigators studying the potential efficacy of magnetic fields in directing
asymmetric syntheses and because of its potential importance as regards the
origin of optical activity, we have attempted to confirm a recent report by
Takahashiet al. (1986), who claimed that phenylglyoxylic acid (XIX) may be
reduced electrochem... hiện toàn bộ
Book reviewsOrigins of life - Tập 25 - Trang 511-512 - 1995
John L. Howland
Nonlinear mathematical models for the origin of asymmetry in biological moleculesOrigins of life - Tập 6 - Trang 317-366 - 1975
Adolf R. Hochstim
The origin of chemical chirality is probably associated with a difference in the
initial concentrations of two separate populations of primeval organic molecules
and possibly even two types of primeval organisms and amplified by nonlinear
kinetic processes leading to the death of one population. This theory, as
originally developed by F. C. Frank of the University of Bristol, is reviewed in
this p... hiện toàn bộ
Phosphorylation of Adenosine with Trimetaphosphate Under Simulated Prebiotic ConditionsOrigins of life - Tập 32 - Trang 219-224 - 2002
Changmei Cheng, Chang Fan, Rong Wan, Chunyuan Tong, Zhiwei Miao, Jing Chen, Yufen Zhao
The phosphorylation of adenosine withtrimetaphosphate in solution, in solid
phase and usingwet-dry cycles was carried out and it was found thatwet-dry
cycles were the most efficient. The catalytic effectsof some metal ions on the
phosphorylation were alsostudied and it was discovered that Ni(II) is the
mosteffective. The combination of wet-dry cycles (4 cycles)and catalysis by
Ni(II) led to an unp... hiện toàn bộ
The Relative Rates of Thiol–Thioester Exchange and Hydrolysis for Alkyl and Aryl Thioalkanoates in WaterOrigins of life - Tập 41 - Trang 399-412 - 2011
Paul J. Bracher, Phillip W. Snyder, Brooks R. Bohall, George M. Whitesides
This article reports rate constants for thiol–thioester exchange (k ex), and for
acid-mediated (k a), base-mediated (k b), and pH-independent (k w) hydrolysis of
S-methyl thioacetate and S-phenyl 5-dimethylamino-5-oxo-thiopentanoate—model
alkyl and aryl thioalkanoates, respectively—in water. Reactions such as
thiol–thioester exchange or aminolysis could have generated molecular complexity
on early... hiện toàn bộ