Oncology and Therapy

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Cost-Effectiveness of PD-L1 Testing in Non-Small Cell Lung Cancer (NSCLC) Using In Vitro Diagnostic (IVD) Versus Laboratory-Developed Test (LDT)
Oncology and Therapy - Tập 10 - Trang 391-409 - 2022
Jason T. Hurwitz, Shannon Vaffis, Amy J. Grizzle, Søren Nielsen, Andrew Dodson, Suzanne Parry
Accurate PD-L1 testing for non-small cell lung cancer (NSCLC) maximizes the benefits of immune checkpoint inhibitor (ICI) drugs like pembrolizumab. False negative test results deny ICI treatments to eligible patients, worsening clinical and economic outcomes, while false positives increase costs by using ICI treatments without their benefits. This study evaluates the cost-effectiveness of PD-L1 te... hiện toàn bộ
Real-World Treatment Patterns for Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer in Europe and the United States
Oncology and Therapy - Tập 4 - Trang 189-197 - 2016
Rita Caldeira, Mark Scazafave
Clinical guidelines generally recommend endocrine therapy over chemotherapy for hormone receptor-positive advanced breast cancer (unless life-threatening metastases are present). This study aimed to assess the real-world treatment patterns of patients with hormone receptor-positive advanced breast cancer in Europe and the United States. Treatment patterns in Europe (France, Germany, Italy, Spain, ... hiện toàn bộ
Cutaneous CD8+ Cytotoxic T-Cell Lymphoma Infiltrates: Clinicopathological Correlation and Outcome of 35 Cases
Oncology and Therapy - Tập 4 - Trang 199-210 - 2016
Marion Wobser, Theresa Reinartz, Sabine Roth, Matthias Goebeler, Andreas Rosenwald, Eva Geissinger
Cytotoxic CD8+ T-cell lymphomas are only rarely encountered and thus remain only poorly characterized. Our aim was to collect and correlate clinical and histological data of CD8+ skin lymphoma infiltrates to obtain a proper subtype assignment of CD8+ skin lymphoma infiltrates and to derive putative prognostic markers thereof. Formalin-fixed and paraffin-embedded (FFPE) tissue of 35 patients with C... hiện toàn bộ
Biosimilar Oncology Drugs in Europe: Regulatory and Pharmacovigilance Considerations
Oncology and Therapy - Tập 4 - Trang 173-182 - 2016
Sara Francescon, Giulia Fornasier, Paolo Baldo
The introduction in clinical practice of pharmaceutical products known as biosimilars, as part of a more complex series of progress in the field of biological drugs, represents an excellent therapeutic resource. A biosimilar drug is a biological/biotechnological drug that is highly similar to an approved reference biologic product. Given their complexity, biosimilars require attention and a contin... hiện toàn bộ
Minimally Invasive Pancreatoduodenectomy: Contemporary Practice, Evidence, and Knowledge Gaps
Oncology and Therapy - Tập 10 - Trang 301-315 - 2022
Jacob Ghotbi, Mushegh Sahakyan, Kjetil Søreide, Åsmund Avdem Fretland, Bård Røsok, Tore Tholfsen, Anne Waage, Bjørn Edwin, Knut Jørgen Labori, Sheraz Yaqub, Dyre Kleive
Minimally invasive pancreatoduodenectomy has gained popularity throughout the last decade. For laparoscopic pancreatoduodenectomy, some high-level evidence exists, but with conflicting results. There are currently no published randomized controlled trials comparing robotic and open pancreatoduodenectomy. Comparative long-term data for patients with pancreatic ductal adenocarcinoma is lacking to da... hiện toàn bộ
Intra-Abdominal and Abdominal Wall Desmoid Fibromatosis
Oncology and Therapy - Tập 4 Số 1 - Trang 57-72 - 2016
James Howard, Raphael E. Pollock
Kết quả sống sót trong ung thư vú và các chỉ thị đại thực bào liên quan đến khối u: Một nghiên cứu tổng hợp và phân tích tổng hợp Dịch bởi AI
Oncology and Therapy - Tập 11 - Trang 27-48 - 2022
Eleanor Allison, Senarath Edirimanne, Jim Matthews, Stephen J. Fuller
Các đại thực bào liên quan đến khối u (TAM) trong ung thư vú có liên quan đến tiên lượng kém. Các nghiên cứu ban đầu về TAM chủ yếu tập trung vào chỉ thị CD68, một chỉ thị thuộc nhóm đại thực bào tổng quát; tuy nhiên, gần đây, ngày càng nhiều nghiên cứu đã sử dụng CD163, một chỉ thị được biểu hiện bởi các đại thực bào M2 kích hoạt theo cách thay thế và các phân nhóm TAM. Chúng tôi giả thuyết rằng ... hiện toàn bộ
#ung thư vú #đại thực bào liên quan đến khối u #CD68 #CD163 #sống sót tổng thể #phân tích tổng hợp
A Narrative Review of Implementing Precision Oncology in Metastatic Castration-Resistant Prostate Cancer in Emerging Countries
Oncology and Therapy - Tập 9 - Trang 311-327 - 2021
Shouki Bazarbashi, Wen-Pin Su, Siew W. Wong, Ramanujam A. Singarachari, Sudhir Rawal, Maria I. Volkova, Diogo A. Bastos
The therapeutic landscape of metastatic castration-resistant prostate cancer (mCRPC) has evolved considerably with the introduction of newer agents, such as poly-ADP ribose polymerase (PARP) inhibitors targeting DNA damage repair mutations. Combining and sequencing novel and existing therapies appropriately is necessary for optimizing the management of mCRPC and ensuring better treatment outcomes.... hiện toàn bộ
The Future of Breast Cancer Research in the Survivorship Field
Oncology and Therapy - - 2023
Davide Soldato, Luca Arecco, Elisa Agostinetto, Maria Alice Franzoi, Elene Mariamidze, S. Begijanashvili, Nicole Brunetti, Stefano Spinaci, Cinzia Solinas, Inês Vaz-Luís, Antonio Di Meglio, Matteo Lambertini
Estimating Public Economic Gains from Early Breast Cancer and Curative Treatment: A Case Study in Human Epidermal Growth Factor Receptor (HER-2) Positive Targeted Therapies
Oncology and Therapy -
Svenn Alexander Hansen, Nikolaos Kotsopoulos, Isabel Monteiro, Ana Ladeiras, Andrew E. Hogan, Filipe Araújo, Mark P. Connolly
Tổng số: 154   
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