Oncologist

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The Molecular Perspective: Cisplatin
Oncologist - Tập 11 Số 3 - Trang 316-317 - 2006
David S. Goodsell
Learning Objective After completing this course, the reader will be able to: Describe the structure and action of cisplatin. Access and take the CME test online and receive 1 AMA PRA category 1 credit at CME.TheOncologist.com
Incorporating Tumor Characteristics to the American Joint Committee on Cancer Breast Cancer Staging System
Oncologist - Tập 22 Số 11 - Trang 1292-1300 - 2017
Mariana Chávez‐MacGregor, Elizabeth A. Mittendorf, Christina A. Clarke, Daphne Y. Lichtensztajn, Kelly K. Hunt, Sharon H. Giordano
Abstract Background The American Joint Committee on Cancer (AJCC) breast cancer staging system provides important prognostic information. The recently published eighth edition incorporates biological markers and recommends the use of a complex “prognostic stage.” In this study, we assessed the relationship between stage, breast cancer subtype, grade, and outcome in a large population-based cohort ... hiện toàn bộ
FDA Approval Summary: Daratumumab for Treatment of Multiple Myeloma After One Prior Therapy
Oncologist - Tập 22 Số 11 - Trang 1347-1353 - 2017
Vishal Bhatnagar, Nicole Gormley, Lola Luo, Yuan Li Shen, Rajeshwari Sridhara, Sriram Subramaniam, Guoxiang Shen, Lian Ma, Stacy S. Shord, Kirsten B. Goldberg, Ann T. Farrell, Amy E. McKee, Richard Pazdur
Abstract On November 21, 2016, the U.S. Food and Drug Administration granted regular approval to daratumumab in combination with lenalidomide and dexamethasone, or bortezomib and dexamethasone, for the treatment of patients with multiple myeloma who have received at least one prior therapy. Approval was based on two randomized, open-label trials in which daratumumab was added to these backbone the... hiện toàn bộ
Surgical Management of Spinal Metastases
Oncologist - Tập 9 Số 2 - Trang 188-196 - 2004
Paul Klimo, Meic H. Schmidt
Abstract Metastatic spread to the spinal column is a growing problem in patients with cancer. It can cause a number of sequelae including pain, instability, and neurologic deficit. If left untreated, progressive myelopathy results in the loss of motor, sensory, and autonomic functions. Except in rare circumstances, treatment is palliative. Traditionally, conventional fractionated external beam rad... hiện toàn bộ
Expanding Criteria for Resectability of Colorectal Liver Metastases
Oncologist - Tập 13 Số 1 - Trang 51-64 - 2008
Timothy M. Pawlik, Richard D. Schulick, Michael A. Choti
Abstract Learning Objectives After completing this course, the reader will be able to: Identify the criteria for hepatic resection of colorectal metastases.Describe strategies for expanding the number of patients who may potentially benefit from hepatic resection.List the factors associated with poor prognosis following hepatic resection. CME Access and take the CME test online and receive 1 AMA P... hiện toàn bộ
Efficacy of First-Line Letrozole Versus Tamoxifen as a Function of Age in Postmenopausal Women with Advanced Breast Cancer
Oncologist - Tập 9 Số 5 - Trang 497-506 - 2004
Henning T. Mouridsen, Hilary A. Chaudri‐Ross
Abstract Learning Objectives After completing this course, the reader will be able to: Identify those patients in both age groups who responded most favorably to first-line therapy with letrozole. Describe the advantages of first-line treatment with letrozole in older patients with advanced breast cancer. Discuss the role of first-line therapy with letrozole in the management of advanced breast ca... hiện toàn bộ
Intravascular Lymphoma: The Oncologist's “Great Imitator”
Oncologist - Tập 11 Số 5 - Trang 496-502 - 2006
Dan Sayam Zuckerman, Rania M. Seliem, Ephraim P. Hochberg
Abstract Learning Objectives After completing this course, the reader will be able to: Describe the clinicopathologic features of IVL that distinguish it from the other large-cell lymphomas.Discuss the diagnostic tests helpful in evaluating a case of suspected IVL.Explain the rationale for treatment approaches in patients with IVL, including the role of hematopoietic stem cell transplantation. Acc... hiện toàn bộ
Current and Emerging Therapies for Advanced Adrenocortical Carcinoma
Oncologist - Tập 16 Số 1 - Trang 36-48 - 2011
Lyndal Tacon, Ruth Prichard, Patsy S. Soon, Bruce G. Robinson, Roderick Clifton‐Bligh, Stan B. Sidhu
AbstractLearning ObjectivesAfter completing this course, the reader will be able to: Review the role and describe the limitations of conventional therapies for adrenocortical carcinoma.Evaluate the current preclinical molecular research contributing to the rational selection of targeted therapies for adrenocortical carcinoma.CME This article is available for continuing medical education credit at ... hiện toàn bộ
Obesity and the Risk for a Hematological Malignancy: Leukemia, Lymphoma, or Myeloma
Oncologist - Tập 15 Số 10 - Trang 1083-1101 - 2010
Marshall A. Lichtman
Abstract The aggregate of epidemiological studies indicates a significantly elevated risk for cancer in people with a high body mass index (BMI); a “dose–response” effect exists with increasing risk as BMI increases from the normal to overweight to obese categories. Successful sustained weight loss decreases future risk. The relationship of being overweight to the risk for leukemia in the aggregat... hiện toàn bộ
Battling the Hematological Malignancies: The 200 Years' War
Oncologist - Tập 13 Số 2 - Trang 126-138 - 2008
Marshall A. Lichtman
Abstract Learning Objectives After completing this course, the reader will be able to: Discuss the advances that led to the current state of management of the hematological malignancies.Describe the remaining major hurdles to curing these diseases in patients who do not respond to current therapy.Identify the strategies needed to reach the goal of cure for most (all) patients. CME Access and take ... hiện toàn bộ
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