Oncologist

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Obesity and the Risk for a Hematological Malignancy: Leukemia, Lymphoma, or Myeloma
Oncologist - Tập 15 Số 10 - Trang 1083-1101 - 2010
Marshall A. Lichtman
Abstract The aggregate of epidemiological studies indicates a significantly elevated risk for cancer in people with a high body mass index (BMI); a “dose–response” effect exists with increasing risk as BMI increases from the normal to overweight to obese categories. Successful sustained weight loss decreases future risk. The relationship of being ove...... hiện toàn bộ
Efficacy and Safety of Methadone as a Second-Line Opioid for Cancer Pain in an Outpatient Clinic: A Prospective Open-Label Study
Oncologist - Tập 21 Số 8 - Trang 981-987 - 2016
Josep Porta-Sales, Cristina Garzón-Rodríguez, Christian Villavicencio‐Chávez, Silvia Llorens-Torromé, Jesús González‐Barboteo
Abstract Introduction. Most clinical reports on methadone rotation describe outcomes in hospitalized patients. The few studies that have included outpatients are retrospective. The aim of this study was to assess the efficacy and safety of methadone as a second-line opioid in adu...... hiện toàn bộ
The Clinical Approach Toward Giant Cell Tumor of Bone
Oncologist - Tập 19 Số 5 - Trang 550-561 - 2014
L. van der Heijden, P. D. S. Dijkstra, Michiel A. J. van de Sande, Judith R. Kroep, Remi A. Nout, C. S. P. van Rijswijk, Judith V.M.G. Bovée, Pancras C.W. Hogendoorn, Hans Gelderblom
AbstractWe provide an overview of imaging, histopathology, genetics, and multidisciplinary treatment of giant cell tumor of bone (GCTB), an intermediate, locally aggressive but rarely metastasizing tumor. Overexpression of receptor activator of nuclear factor κB ligand (RANKL) by mononuclear neoplastic stromal cells promotes recruitment of numerous reactive multinu...... hiện toàn bộ
FDA Report: Eculizumab (Soliris®) for the Treatment of Patients with Paroxysmal Nocturnal Hemoglobinuria
Oncologist - Tập 13 Số 9 - Trang 993-1000 - 2008
Andrew Dmytrijuk, Kathy Robie‐Suh, Martin H. Cohen, Dwaine Rieves, K Weiss, Richard Pazdur
Abstract Learning Objectives After completing this course, the reader will be able to: Describe the mechanism of action of eculizumab in PNH.Discuss the efficacy findings upon which the approval of eculizumab was based.Manage the safety concerns surrounding the use of eculizumab ...... hiện toàn bộ
CXCR4 Expression in Early Breast Cancer and Risk of Distant Recurrence
Oncologist - Tập 14 Số 12 - Trang 1182-1188 - 2009
Fabrice André, Weiya Xia, Rosa Conforti, Yongkun Wei, Thomas Boulet, Gorana Tomasic, M. Spielmann, M. Zoubir, Narjiss Berrada, R. Arriagada, Gabriel N. Hortobágyi, Mien‐Chie Hung, Lajos Pusztai, Suzette Delaloge, Stefan Michiels, Massimo Cristofanilli
Abstract Learning Objectives After completing this course, the reader will be able to: Assess CXCR4 expression in the primary tumor for use as an indicator of a higher risk for bone metastasis in early breast cancer.Evaluate the relationship between CXCR4 expression and the occur...... hiện toàn bộ
Age-related Differences in Recall of Information and Handling of Chemotherapy-related Side Effects in Cancer Patients: The ReCap Study
Oncologist - Tập 27 Số 2 - Trang e185-e193 - 2022
Cecilia Margareta Lund, Marta Kramer Mikkelsen, Susann Theile, Hanne Marie Michelsen, Martin Schultz, Stéphane Oudard, Dorte Nielsen
Abstract Background To prevent severe toxicity and hospital admissions, adequate management and recall of information about side effects are crucial and health literacy plays an important role. If age-related factors impact recall of given information and handling of side effects...... hiện toàn bộ
Pheochromocytoma: Current Approaches and Future Directions
Oncologist - Tập 13 Số 7 - Trang 779-793 - 2008
Joel T. Adler, Goswin Y. Meyer‐Rochow, Herbert Chen, Diana E. Benn, Bruce G. Robinson, Rebecca S. Sippel, Stan B. Sidhu
Abstract Learning Objectives After completing this course, the reader should be able to: Use current practice methods in the diagnosis of pheochromocytomas.Employ current practice methods in the treatment of pheochromocytomas.Evaluate the current molecular research that contribut...... hiện toàn bộ
Current Knowledge and Future Directions of the Selective Epidermal Growth Factor Receptor Inhibitors Erlotinib (Tarceva®) and Gefitinib (Iressa®)
Oncologist - Tập 10 Số 8 - Trang 579-589 - 2005
Wandena S. Siegel-Lakhai, Jos H. Beijnen, Jan H.M. Schellens
AbstractThe CME activity for this article is forthcoming.Access and take the CME test online and receive 1 hour of AMA PRA category 1 credit at CME.TheOncologist.comGefitinib (Iressa®; AstraZeneca Pharmaceuticals, Wilmington, DE, http://www.astrazeneca-us.com...... hiện toàn bộ
Chemotherapy of Metastatic Breast Cancer: What to Expect in 2001 and Beyond
Oncologist - Tập 6 Số 2 - Trang 133-146 - 2001
Francisco J. Esteva, Vicente Valero, Lajos Pusztai, Laura Boehnke-Michaud, Aman U. Buzdar, Gabriel N. Hortobágyi
Abstract Chemotherapy plays an important role in the management of metastatic breast cancer. The anthracyclines (doxorubicin, epirubicin) and the taxanes (paclitaxel, docetaxel) are considered the most active agents for patients with advanced breast cancer. Traditionally, the anthracyclines have been used in combination with cyclophosphamide and 5-fl...... hiện toàn bộ
Treating Fatigue in Cancer Patients
Oncologist - Tập 8 Số S1 - Trang 10-14 - 2003
Ann Berger
Abstract Learning Objectives After completing this course, the reader will be able to: Explain the randomized controlled trials involving cancer patients with fatigue. Describe the different etiologies of fatigue. Describe the interventions (pha...... hiện toàn bộ
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