Increased globulin and its association with hemorrhagic transformation in patients receiving intra-arterial thrombolysis therapyNeuroscience Bulletin - Tập 30 - Trang 469-476 - 2014
Yingqi Xing, Zhen-Ni Guo, Shuo Yan, Hang Jin, Shouchun Wang, Yi Yang
Previous studies have identified a diverse set of predisposing factors for the occurrence of hemorrhagic transformation (HT), but the independent clinical predictors of HT after intraarterial thrombolysis have not been determined. In this retrospective study, we investigated the characteristics of patients with or without HT who had received intra-arterial thrombolysis therapy, using biochemical a...... hiện toàn bộ
Projections from Infralimbic Cortex to Paraventricular Thalamus Mediate Fear Extinction RetrievalNeuroscience Bulletin - Tập 37 - Trang 229-241 - 2020
Yan Tao, Cheng-Yun Cai, Jia-Yun Xian, Xiao-Lin Kou, Yu-Hui Lin, Cheng Qin, Hai-Yin Wu, Lei Chang, Chun-Xia Luo, Dong-Ya Zhu
The paraventricular nucleus of the thalamus (PVT), which serves as a hub, receives dense projections from the medial prefrontal cortex (mPFC) and projects to the lateral division of central amygdala (CeL). The infralimbic (IL) cortex plays a crucial role in encoding and recalling fear extinction memory. Here, we found that neurons in the PVT and IL were strongly activated during fear extinction re...... hiện toàn bộ
Internal States Influence the Representation and Modulation of Food Intake by Subthalamic NeuronsNeuroscience Bulletin - Tập 36 - Trang 1355-1368 - 2020
Haichuan Wu, Xiang Yan, Dongliang Tang, Weixin Gu, Yiwen Luan, Haijiang Cai, Chunyi Zhou, Cheng Xiao
Deep brain stimulation of the subthalamic nucleus (STN) is an effective therapy for motor deficits in Parkinson’s disease (PD), but commonly causes weight gain in late-phase PD patients probably by increasing feeding motivation. It is unclear how STN neurons represent and modulate feeding behavior in different internal states. In the present study, we found that feeding caused a robust activation ...... hiện toàn bộ
β-Catenin Deletion in Regional Neural Progenitors Leads to Congenital Hydrocephalus in MiceNeuroscience Bulletin - Tập 38 - Trang 81-94 - 2021
Lin Ma, Yanhua Du, Xiangjie Xu, Hexi Feng, Yi Hui, Nan Li, Guanyu Jiang, Xiaoqing Zhang, Xiaocui Li, Ling Liu
Congenital hydrocephalus is a major neurological disorder with high rates of morbidity and mortality; however, the underlying cellular and molecular mechanisms remain largely unknown. Reproducible animal models mirroring both embryonic and postnatal hydrocephalus are also limited. Here, we describe a new mouse model of congenital hydrocephalus through knockout of β-catenin in Nkx2.1-expressing reg...... hiện toàn bộ
The SACT Template: A Human Brain Diffusion Tensor Template for School-age ChildrenNeuroscience Bulletin - Tập 38 - Trang 607-621 - 2022
Congying Chu, Haoran Guan, Sangma Xie, Yanpei Wang, Jie Luo, Gai Zhao, Zhiying Pan, Mingming Hu, Weiwei Men, Shuping Tan, Jia-Hong Gao, Shaozheng Qin, Yong He, Lingzhong Fan, Qi Dong, Sha Tao
School-age children are in a specific development stage corresponding to juvenility, when the white matter of the brain experiences ongoing maturation. Diffusion-weighted magnetic resonance imaging (DWI), especially diffusion tensor imaging (DTI), is extensively used to characterize the maturation by assessing white matter properties in vivo. In the analysis of DWI data, spatial normalization is c...... hiện toàn bộ
Transcriptome Analysis Identifies SenZfp536, a Sense LncRNA that Suppresses Self-renewal of Cortical Neural ProgenitorsNeuroscience Bulletin - Tập 37 - Trang 183-200 - 2020
Kuan Tian, Andi Wang, Junbao Wang, Wei Li, Wenchen Shen, Yamu Li, Zhiyuan Luo, Ying Liu, Yan Zhou
Long non-coding RNAs (lncRNAs) regulate transcription to control development and homeostasis in a variety of tissues and organs. However, their roles in the development of the cerebral cortex have not been well elucidated. Here, a bioinformatics pipeline was applied to delineate the dynamic expression and potential cis-regulating effects of mouse lncRNAs using transcriptome data from 8 embryonic t...... hiện toàn bộ
Divergent Projection Patterns Revealed by Reconstruction of Individual Neurons in Orbitofrontal CortexNeuroscience Bulletin - Tập 37 Số 4 - Trang 461-477 - 2021
Junjun Wang, Pei Sun, Xiaohua Li, Sen Jin, Anan Li, Jianxia Kuang, Ning Li, Yadong Gang, Rui Guo, Shaoqun Zeng, Fuqiang Xu, Yuhui Zhang