Medical Oncology

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Comorbidity assessment and adjuvant radiochemotherapy in elderly affected by glioblastoma
Medical Oncology - Tập 29 Số 5 - Trang 3467-3471 - 2012
Fiorentino, Alba, Caivano, Rocchina, Chiumento, Costanza, Cozzolino, Mariella, Clemente, Stefania, Pedicini, Piernicola, Fusco, Vincenzo
To assess the role of comorbidity on outcome in elderly patients with glioblastoma treated with radiotherapy plus concomitant and adjuvant Temozolomide, patients over 65 years with glioblastoma, who underwent surgical resection or biopsy and radiochemotherapy, were evaluated. The Adjusted-Age Charlson Comorbidity Index and the Adult Comorbidity Evaluation-27 were used to assess comorbidity. F...... hiện toàn bộ
Delta-like ligand 4 (DLL4) in the plasma and neoplastic tissues from breast cancer patients: correlation with metastasis
Medical Oncology - Tập 31 - Trang 1-6 - 2014
Emmanuel Kontomanolis, Marianthi Panteliadou, Alexandra Giatromanolaki, Stamatia Pouliliou, Eleni Efremidou, Vassilios Limberis, Georgios Galazios, Efthimios Sivridis, Michael I. Koukourakis
Delta-like ligand 4 (DLL4) is a ligand of the notch pathway. In tumor angiogenesis, DLL4 switches to vascular maturation by providing a negative feedback on VEGFR2 activity. We investigated the expression of DLL4 in the plasma and cancer tissues from breast cancer patients. Plasma samples were collected from 18 women with localized breast cancer, six women with benign breast disease and from six p...... hiện toàn bộ
The adeno-associated virus-mediated HSV-TK/GCV suicide system: a potential strategy for the treatment of bladder carcinoma
Medical Oncology - Tập 29 - Trang 1938-1947 - 2011
Jian Gang Pan, Xing Zhou, Runqi Luo, Rui Fa Han
Novel treatment strategies such as gene therapy are warranted in view of the failure of current treatment approaches to cure a high percentage of patients with advanced bladder cancers. The emergence of cancer gene therapy potentially offers a number of exciting treatments. The majority of approaches involve strategies to suppress the function of activated oncogenes to restore the expression of fu...... hiện toàn bộ
Identifications of genetic differences between metastatic and non-metastatic osteosarcoma samples based on bioinformatics analysis
Medical Oncology - Tập 32 - Trang 1-8 - 2015
Baoyong Sun, Fangxin Wang, Min Li, Mingshan Yang
To investigate the differences in gene expression level between metastatic and non-metastatic osteosarcoma (OS) samples and the potential mechanism. Gene expression profile data GSE9508 were downloaded from Gene Expression Omnibus database to identify the differentially expressed genes (DEGs) between metastatic, non-metastatic OS samples, and normal control samples via SAM method. Function expres...... hiện toàn bộ
Renal safety and osteonecrosis of the jaw in cancer patients receiving intravenous bisphosphonates
Medical Oncology - Tập 27 - Trang 568-568 - 2009
Sercan Aksoy, Omer Dizdar, Kadri Altundag
A closer look to the new frontier of artificial intelligence in the percutaneous treatment of primary lesions of the liver
Medical Oncology - Tập 37 - Trang 1-7 - 2020
M. Citone, F. Fanelli, G. Falcone, F. Mondaini, D. Cozzi, V. Miele
The purpose of thermal ablation is induction of tumor death by means of localized hyperthermia resulting in irreversible cellular damage. Ablative therapies are well-recognized treatment modalities for HCC lesions and are considered standard of care for HCC nodules < 3 cm in diameter in patients not suitable for surgery. Effective lesion treatment rely on complete target volume ablation. Technical...... hiện toàn bộ
LRG1 suppresses the migration and invasion of hepatocellular carcinoma cells
Medical Oncology - Tập 32 - Trang 1-10 - 2015
Yurong Zhang, Qin Luo, Ning Wang, Fangyuan Hu, Haojie Jin, Tianxiang Ge, Cun Wang, Wenxin Qin
Hepatocellular carcinoma (HCC) is a malignant tumor driven by complex pathological mechanisms and is characterized by fast progression and poor prognosis. The main cause of death in HCC patients is tumor metastasis. However, underlying molecular mechanisms of metastasis are largely unknown in HCC. In the present study, a novel metastasis-related gene, leucine-rich-alpha-2-glycoprotein 1 (LRG1), w...... hiện toàn bộ
Volumetric modulated arc therapy (VMAT) to deliver nodal irradiation in breast cancer patients
Medical Oncology - Tập 35 - Trang 1-8 - 2017
Giuseppe Carlo Iorio, Pierfrancesco Franco, Elena Gallio, Stefania Martini, Francesca Arcadipane, Sara Bartoncini, Nadia Rondi, Francesca Romana Giglioli, Ada Ala, Mario Airoldi, Michela Donadio, Corrado De Sanctis, Isabella Castellano, Umberto Ricardi
To evaluate feasibility, safety, toxicity profile and dosimetric results of volumetric modulated arc therapy (VMAT) to deliver regional nodal irradiation (RNI) after either mastectomy or breast conservation (BCS) in high-risk breast cancer patients. Between January 2015 and January 2017, a total of 45 patients were treated with VMAT to deliver RNI together with whole breast or post-mastectomy radi...... hiện toàn bộ
Statin use may improve clinicopathological characteristics and recurrence risk of invasive breast cancer
Medical Oncology - Tập 31 - Trang 1-3 - 2014
Mehmet Ali Nahit Şendur, Sercan Aksoy, Ozan Yazıcı, Nuriye Y. Ozdemir, Nurullah Zengin, Kadri Altundag
Genetic variations in transcription factor 7-like 2 (TCF7L2) gene: association of TCF7L2 rs12255372(G/T) or rs7903146(C/T) with breast cancer risk and clinico-pathological parameters
Medical Oncology - Tập 29 Số 2 - Trang 411-417 - 2012
Rakesh Naidu, Cheng Har Yip, Nur Aishah Mohd Taib
Tổng số: 3,349   
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