Mouse models of atherosclerosis: a historical perspective and recent advancesLipids in Health and Disease - Tập 16 - Trang 1-11 - 2017
Yee Ting Lee, Hiu Yu Lin, Yin Wah Fiona Chan, Ka Hou Christien Li, Olivia Tsz Ling To, Bryan P Yan, Tong Liu, Guangping Li, Wing Tak Wong, Wendy Keung, Gary Tse
Atherosclerosis represents a significant cause of morbidity and mortality in
both the developed and developing countries. Animal models of atherosclerosis
have served as valuable tools for providing insights on its aetiology,
pathophysiology and complications. They can be used for invasive interrogation
of physiological function and provide a platform for testing the efficacy and
safety of differe... hiện toàn bộ
Depot-specific differences in perilipin and hormone-sensitive lipase expression in lean and obeseLipids in Health and Disease - Tập 8 - Trang 1-10 - 2009
Hind Ray, Claudie Pinteur, Vincent Frering, Michel Beylot, Valérie Large
Mainly dependent on hormone-sensitive lipase, lipolysis is differently impaired
between fat depots in human obesity. Perilipin A expression is a critical
element in adipocyte lipolysis. The present study aimed at comparing expression
and subcellular distribution of perilipin and hormone-sensitive lipase in two
abdominal adipose tissues of lean and obese women. We examined whether regional
differen... hiện toàn bộ
4-cholesten-3-one decreases breast cancer cell viability and alters membrane raft-localized EGFR expression by reducing lipogenesis and enhancing LXR-dependent cholesterol transportersLipids in Health and Disease - Tập 18 - Trang 1-15 - 2019
Josiane Elia, Delphine Carbonnelle, Cédric Logé, Lucie Ory, Jean-Michel Huvelin, Mona Tannoury, Mona Diab-Assaf, Karina Petit, Hassan Nazih
The alteration of lipid metabolism in cancer cells is recognized as one of the
most important metabolic hallmarks of cancer. Membrane rafts defined as plasma
membrane microdomains enriched in cholesterol and sphingolipids serve as
platforms for signaling regulation in cancer. The main purpose of this study was
to evaluate the effect of the cholesterol metabolite, 4-cholesten-3-one, on
lipid metabo... hiện toàn bộ
Adiposity mediates the association between whole grain consumption, glucose homeostasis and insulin resistance: findings from the US NHANESLipids in Health and Disease - Tập 17 - Trang 1-9 - 2018
Mohsen Mazidi, Niki Katsiki, Andre Pascal Kengne, Dimitri P. Mikhailidis, Maciej Banach
Growing evidence suggests an inverse association between whole grain (WG)
consumption and insulin resistance (IR) or inflammation. However, it is still
unclear whether adiposity plays a role in this relationship. We investigated
whether the associations between WG intake with IR, glucose homeostasis and
inflammation are mediated by adiposity in US adults. The 2005–2010 National
Health and Nutritio... hiện toàn bộ
High prevalence of dyslipidemia and associated risk factors among rural Chinese adultsLipids in Health and Disease - Tập 13 - Trang 1-11 - 2014
Guo-Zhe Sun, Zhao Li, Liang Guo, Ying Zhou, Hong-Mei Yang, Ying-Xian Sun
Dyslipidemia is a key independent modifiable risk factor for Cardiovascular
Disease, which is a leading contributor to morbidity and mortality in most
developed and developing countries. This study was designed to investigate the
current epidemiological features of dyslipidemia among adults in rural China.
Between January 2013 and August 2013, we conducted a cross-sectional study
involving 11,956 ... hiện toàn bộ
Plasmalogens and Alzheimer’s disease: a reviewLipids in Health and Disease - - 2019
Xiao Q. Su, Junming Wang, Andrew J. Sinclair
Growing evidence suggests that ethanolamine plasmalogens (PlsEtns), a subtype of
phospholipids, have a close association with Alzheimer’s disease (AD). Decreased
levels of PlsEtns have been commonly found in AD patients, and were correlated
with cognition deficit and severity of disease. Limited studies showed positive
therapeutic outcomes with plasmalogens interventions in AD subjects and in
rode... hiện toàn bộ