Laryngoscope

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HPV status in unknown primary head and neck cancer: Prognosis and treatment outcomes
Laryngoscope - Tập 129 Số 3 - Trang 684-691 - 2019
Shayan Cheraghlou, Sina J. Torabi, Zain Husain, Michael Otremba, Heather Edwards, Saral Mehra, Wendell G. Yarbrough, Barbara Burtness, Benjamin L. Judson
ObjectivesApproximately 3% to 9% of head and neck cancer presents with a metastatic node and no identifiable primary tumor. These cases of head and neck carcinoma of unknown primary (HNCUP) present a therapeutic challenge. Therapy of this disease varies based on factors such as institutional, surgeon, and patient preference. Evidence demonstrating the outcomes associated with these therapies for H... hiện toàn bộ
Survival Outcomes in Sinonasal Poorly Differentiated Squamous Cell Carcinoma
Laryngoscope - Tập 131 Số 4 - 2021
Feras Ackall, Khalil Issa, Ian Barak, Jordan I. Teitelbaum, David W. Jang, Se-hoon Jung, Bradley J. Goldstein, Ricardo L. Carrau, Ralph Abi Hachem
ObjectiveSinonasal squamous cell carcinoma (SCC) is rare with no consensus on treatment regimen. Our goal is to analyze treatment outcomes in poorly differentiated SCC (PDSCC) using a large national database.Study DesignRetrospective database study.MethodsThe National Cancer Database was queried for sinonasal invasive SCC, grade 3 (poorly differentiated) from 2004 to 2014. Patient demographics and... hiện toàn bộ
Confocal Scanning Laser Microscopy Evidence of Biofilms in Patients With Chronic Rhinosinusitis
Laryngoscope - Tập 117 Số 7 - Trang 1302-1306 - 2007
Alkis J. Psaltis, Kien R. Ha, Achim Beule, Lor Wai Tan, Peter‐John Wormald
AbstractObjectives: The recent detection of bacterial biofilms on the sinus mucosa of patients with chronic rhinosinusitis (CRS) has implicated biofilms in the pathogenesis of this condition. Electron microscopy has been the main modality used to document the presence of biofilms on sinus tissue, however, it has inherent problems associated with tissue preparation and sampling. Recently, Confocal ... hiện toàn bộ
Bacterial Biofilms on the Sinus Mucosa of Human Subjects With Chronic Rhinosinusitis
Laryngoscope - Tập 116 Số 7 - Trang 1121-1126 - 2006
Alicia R. Sanderson, Jeff G. Leid, Darrell H. Hunsaker
AbstractIntroduction: Chronic rhinosinusitis (CRS) is a common disease poorly controlled by antibiotics. Postulated etiologies of CRS include allergy, fungi, functional factors, and biofilm.Objectives: We presented a preliminary study demonstrating bacterial biofilms' presence on the sinus mucosa of patients with CRS using fluorescent in situ hybridization (FISH). The advantage of FISH in biofilm ... hiện toàn bộ
Bacterial Biofilms in Surgical Specimens of Patients with Chronic Rhinosinusitis
Laryngoscope - Tập 115 Số 4 - Trang 578-582 - 2005
Jose A. Sanclement, Paul Webster, John G. Thomas, Hassan H. Ramadan
Targeted imaging modality selection for bacterial biofilms in chronic rhinosinusitis
Laryngoscope - Tập 120 Số 2 - Trang 427-431 - 2010
Andrew Foreman, Deepti Singhal, Alkis J. Psaltis, Peter‐John Wormald
AbstractObjectives/Hypothesis:Biofilms are increasingly recognized as having an etiological role in chronic rhinosinusitis (CRS). Research into biofilms in CRS currently relies on microscopic imaging techniques, none of which are universally accepted. This study compares LIVE/DEAD BacLight (Invitrogen Corp., Carlsbad, CA) staining and fluorescence in situ hybridization (FISH), both utilizing the c... hiện toàn bộ
Criteria for Success in Pediatric Functional Endonasal Sinus Surgery
Laryngoscope - Tập 106 Số 7 - Trang 869-873 - 1996
Ramzi T. Younis, Rande H. Lazar
AbstractFunctional endonasal sinus surgery (FESS) is widely used in the treatment of chronic sinusitis in adults and children. Although success rates of 80% to 93% have been reported, no criteria for success or improvement have been suggested. Standardized measures are needed to assess the outcome of FESS and to compare the results obtained by different surgical teams and for various patient group... hiện toàn bộ
Genetic Susceptibility to Head and Neck Cancer: Interaction Between Nutrition and Mutagen Sensitivity
Laryngoscope - Tập 107 Số 6 - Trang 765-781 - 1997
Stimson P. Schantz, Zuo‐Feng Zhang, Margaret S. Spitz, Ming Sun, Tao Hsu
AbstractThe development of head and neck cancer may depend not only on exposure to environmental carcinogens but also on a genetically based susceptibility to carcinogen‐induced damage. This thesis presents a case‐control study that demonstrates the significance of mutagen sensitivity, a measure of an individual's intrinsic DNA repair capacity against free radical damage, as a risk factor for the ... hiện toàn bộ
Symposium continued. Nasal mucous transport and our ambient air
Laryngoscope - Tập 93 Số 1 - Trang 58-62 - 1983
Donald F. Proctor
AbstractThe nose usually serves to conduct air in and out of the lungs; but it also defends the body against airborne noxious materials and modifies the physical condition of inspired air prior to its arrival in the lungs. A major factor in these physiological functions is mucociliary clearance which depends on the secretion of airway secretions and ciliary activity. This function is impaired by c... hiện toàn bộ
Premalignant epithelium and microinvasive cancer of the vocal fold: The evolution of phonomicrosurgical management
Laryngoscope - Tập 105 Số S1 - Trang 1-44 - 1995
Steven M. Zeitels
AbstractPhonomicrosurgical treatment of premalignant vocal fold epithelium and microinvasive cancer combines principles of surgical oncology with advanced laryngoscopic microsurgical‐techniques. This treatment is guided by mucosal‐wave theory of voice production and strives not only to cure the disease but also to achieve optimal vocal function.Surgical techniques developed during the past two cen... hiện toàn bộ
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