Journal of Pharmaceutical Innovation

Công bố khoa học tiêu biểu

* Dữ liệu chỉ mang tính chất tham khảo

Sắp xếp:  
Development of Tamoxifen In Situ Gel Nanoemulsion for Ocular Delivery in Photoreceptor Degeneration Disorder: In Vitro Characterization, 131I-Radiolabeling, and In Vivo Biodistribution Studies
Journal of Pharmaceutical Innovation - Tập 18 - Trang 369-380 - 2022
Mohamed H. Aboumanei, Ashgan Fouad Mahmoud
The aim of our work is to develop an in situ ocular gellan gum–based nanoemulsion (NE) of tamoxifen TAM as an alternative drug delivery system to the oral route for the treatment of photoreceptor degeneration disorder. Six pseudoternary phase diagrams were developed using oil (oleic acid), surfactants (Tween 80 or Tween 20), a co-surfactant (polyethylene glycol 400), and water. The particle size, ...... hiện toàn bộ
Quality KPIs in Pharmaceutical and Food Industry
Journal of Pharmaceutical Innovation - Tập 8 - Trang 205-211 - 2013
Marianne Torkko, Anu Linna, Nina Katajavuori, Anne Mari Juppo
This study aims to investigate what type of quality key performance indicators (KPIs) companies use and how they utilize the results of these KPIs. This e-mail survey is aimed at the personnel in the pharmaceutical and the food industries of Finland responsible for quality. Quality KPIs were similar for both the pharmaceutical and food industries with some differences existing in their usage and r...... hiện toàn bộ
An Integrated Real-time Monitoring and Statistical Process Control Approach for Coating Process and Product Quality via In-line Optical Coherence Tomography
Journal of Pharmaceutical Innovation - Tập 18 - Trang 1870-1878 - 2023
Stephan Sacher, Elisabeth Fink, Vanessa Herndler, Willibald Stumptner, Anna Peter, Manuel Zettl, Maxwell Korang-Yeboah, Xin Feng, Huiquan Wu, Johannes G. Khinast
The thickness and other quality aspects of pharmaceutical coatings can be significantly impacted by coating process conditions. Under certain circumstances, they can notably influence the drug product performance such as dissolution profiles. Typically, a target coating thickness range is defined in the coating process. The coating thickness is conventionally measured off-line via weight or diamet...... hiện toàn bộ
NIR spectrometry for the characterization of fuel components in a novel tamper-resistant pill bottle
Journal of Pharmaceutical Innovation - Tập 1 - Trang 54-61 - 2006
Joseph P. Medendorp, Jason A. Fackler, Tom Henninger, Bill Dieter, Robert A. Lodder
The purpose of this paper is twofold: (i) to present the Pill Safe, a novel design for a tamper-resistant prescription container, and (ii) to present use of near-infrared (NIR) spectrometry for characterization of fuel components and prediction of the burn characteristics of the fuel mixtures used to destroy tablets in the Pill Safe. In the safe, drug tablets are stacked next to fuel and attempts ...... hiện toàn bộ
Response Surface Methodology Optimization of Microwave-Assisted Polysaccharide Extraction from Algerian Jujube (Zizyphus lotus L.) Pulp and Peel
Journal of Pharmaceutical Innovation - Tập 16 Số 4 - Trang 630-642 - 2021
Farida Berkani, Farid Dahmoune, Sabiha Achat, Sofiane Dairi, Nabil Kadri, Sabrina Zeghichi-Hamri, Amina Abbou, Imane Benzitoune, Khadidja Adel, Hocine Remini, Amine Belbahi, Khodir Madani
Design and Optimization of Novel Taste-Masked Medicated Chocolates of Dextromethorphan with In vitro and In vivo Taste Evaluation
Journal of Pharmaceutical Innovation - Tập 17 - Trang 376-390 - 2020
Rahat Fatima Naqvi, Ahmad Khan, Muhammad Farooq Umer, Obaidullah Malik, Nisar Ahmad Shahwani
Dextromethorphan (DXM) is exceptionally bitter, yet the most widely used antitussive agents worldwide. It belongs to BCS class-II of pharmaceutical agents because of its poor water solubility; this is why it is only available in its hydrobromide salt form either in liquid or in solid formulations in the market. This water-soluble salt of the drug releases its content to a greater extent in salivar...... hiện toàn bộ
Influence of Extraction Variables on Free Radical Scavenging Potential of Nelumbo nucifera Seed Kernel: Optimization by Response Surface Methodology
Journal of Pharmaceutical Innovation - Tập 15 - Trang 627-640 - 2019
Haq Nawaz, Muhammad Aslam Shad, Sabiha Tahir Abbasi
The extraction of phytochemical compounds has ever remained confusing and problematic for the researcher and manufacturers. The diversity in extraction conditions may influence the biological activities of the phytochemical compounds. The present study was planned to optimize the influence of four extraction variables on free radical scavenging potential of Nelumbo nucifera seed kernel (NNSK) extr...... hiện toàn bộ
Synthesis and Characterization of Naringenin-Loaded Chitosan-Dextran Sulfate Nanocarrier
Journal of Pharmaceutical Innovation - Tập 16 - Trang 269-278 - 2020
Shruthi Muralidharan, Kumaran Shanmugam
The present study focused on synthesis and characterization of polymeric nanocarrier for the hydrophobic drug, naringenin (Nar), using chitosan (CS) and dextran sulfate (DS). CSDS-Nar and blank CSDS nanoparticles were prepared by complex coacervation technique. The nanoparticles were characterized by scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FTIR), X-ray diffract...... hiện toàn bộ
Editorial: Wrapping Up 2021 and Looking Forward to 2022
Journal of Pharmaceutical Innovation - Tập 16 - Trang 575-575 - 2021
Stephen Scypinski
pH Switchable LLC Nanoparticles Targeting Colon: Optimization Using D-Optimal Design
Journal of Pharmaceutical Innovation - Tập 18 - Trang 128-143 - 2022
Prakash Rajak, Lila Kanta Nath, Biman Bhuyan
To design pH switchable LLC (lyotropic liquid crystal) nanoparticles with the goal of exclusively delivering 5-Fluorouracil (5-FU) in the colonic region of GIT for the treatment of colon cancer. The proportions of monoolein (MO), oleic acid (OA), and pluronic F127 were chosen using the quadratic model of D-optimal mixture design for LLC nanoparticle batches. The formulations were characterized and...... hiện toàn bộ
Tổng số: 557   
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 10