Complete remission of an early-stage laryngeal cancer under combined pembrolizumab and chemotherapy treatment of a synchronous lung adenocarcinomaJournal of Otolaryngology - Head & Neck Surgery - - 2022
Maximilian Linxweiler, Jan Philipp Kühn, Christian Neubert, Fadi Khreish, Benedikt Balensiefer, Mathias Wagner, Bernhard Schick
Anti-PD1-Checkpoint inhibition (CI) is an established treatment of recurrent and/or metastatic head and neck cancer. A potential benefit from CI in early-stage disease that is usually treated by radiation or surgery has not been investigated so far and is currently not addressed in clinical trials. A 58-year-old man was diagnosed with a cT2 supraglottic laryngeal cancer and a synchronous metastasi...... hiện toàn bộ
Evaluation of the utricular and saccular function using oVEMPs and cVEMPs in BPPV patientsJournal of Otolaryngology - Head & Neck Surgery - Tập 45 - Trang 1-6 - 2016
Hui Xu, Fa-ya Liang, Liang Chen, Xi-cheng Song, Michael Chi Fai Tong, Jiun Fong Thong, Qing-quan Zhang, Yan Sun
It is well-known that ocular vestibular evoked myogenic potentials (oVEMPs) predominantly reflect utricular function whilst cervical vestibular evoked myogenic potentials (cVEMPs) reflect saccular function. To date, there are no published reports on the systemic evaluation of utricular and saccular function in benign paroxysmal positional vertigo (BPPV), nor are there any reports on the difference...... hiện toàn bộ
Redox homeostasis dysregulation in noise-induced hearing loss: oxidative stress and antioxidant treatmentJournal of Otolaryngology - Head & Neck Surgery - Tập 52 - Trang 1-13 - 2023
Yuhang Zhou, Chaoyou Fang, Ling Yuan, Mengchen Guo, Xinyi Xu, Anwen Shao, Anke Zhang, Danyang Zhou
Noise exposure is an important cause of acquired hearing loss. Studies have found that noise exposure causes dysregulated redox homeostasis in cochlear tissue, which has been recognized as a signature feature of hearing loss. Oxidative stress plays a pivotal role in many diseases via very complex and diverse mechanisms and targets. Reactive oxygen species are products of oxidative stress that exer...... hiện toàn bộ
Validity and reliability of a french version of the olfactory disorders questionnaireJournal of Otolaryngology - Head & Neck Surgery - Tập 51 - Trang 1-6 - 2022
Jérôme R. Lechien, Luigi A. Vaira, Serge D. Le Bon, Roxane Geerts, Paolo Boscolo-Rizzo, Sven Saussez
To validate a French version of the Olfactory Disorders Questionnaire (Fr-ODQ).
Patients with olfactory disorder (OD) and controls were enrolled from two medical centers. Individuals completed the Fr-ODQ and the French version of the sinonasal outcome tool-22 (SNOT-22). The extended Sniffin'Sticks procedure was used to test odor Threshold, Discrimination, and Identification (TDI). Cronbach’s alph...... hiện toàn bộ
Do patients regret having in-office vocal fold injections for glottic insufficiency?Journal of Otolaryngology - Head & Neck Surgery - Tập 52 - Trang 1-11 - 2023
Alice Q. Liu, Yunqi Ji, Amanda Hu
In-office vocal fold injections (VFI) are an effective treatment for glottic insufficiency. The primary objective of this study was to assess if patients reported decisional regret after VFI. Secondary objectives included determining if variables were associated with lower decisional regret. Case–control study of patients who underwent in-office VFIs for glottic insufficiency from August 2017 to D...... hiện toàn bộ
Improving exposure for transoral oropharyngeal surgery with the floor of mouth window: a cadaveric feasibility studyJournal of Otolaryngology - Head & Neck Surgery - Tập 48 - Trang 1-7 - 2019
Jeffson Chung, Adam Bender-Heine, H. Wayne Lambert
Transoral robotic and laser surgery is rising in popularity due to the increasing incidence of Human Papilloma Virus (HPV) related oropharyngeal cancer. However, adequate exposure of the tongue base remains a major hurdle in many cases. This study introduces a novel surgical technique called the Floor of Mouth Window, which can be used to improve tongue base exposure at the time of transoral surge...... hiện toàn bộ
Efficacy and safety of paranasal sinus balloon catheter dilation in pediatric chronic rhinosinusitis: a systematic reviewJournal of Otolaryngology - Head & Neck Surgery - Tập 49 - Trang 1-10 - 2020
Ahmad A. Mirza, Hatim Y. Shawli, Talal A. Alandejani, Sattam M. Aljuaid, Mahmoud Alreefi, Razan A. Basonbul, Shahad K. Alhomaiani, Banan A. Althobaity, Dhuha A. Alhumaidi, Faisal Zawawi
Chronic rhinosinusitis (CRS) negatively affects quality of life (QoL), and balloon catheter sinuplasty (BCS) has shown good outcomes in adult patients. However, there has not been much research on the effects of BCS on pediatric patients. The objective of this review is to systematically assess the literature for studies demonstrating the effectiveness and safety of BCS in pediatric CRS patients. ...... hiện toàn bộ
Clinicopathological features and treatment outcomes of the rare, salivary duct carcinoma of parotid glandJournal of Otolaryngology - Head & Neck Surgery - - 2016
Khalid Hussain AL-Qahtani, Mutahir A. Tunio, Yasser Bayoumi, Venkada Manickam Gurusamy, Fahad Ahmed A. Bahamdain, Hanadi Fatani
Salivary ductal carcinoma (SDC) of parotid gland is a rare and aggressive entity; accounting for 1–3 % of all malignant salivary gland tumors, 0.2 % of epithelial salivary gland neoplasms, 0.5 % of salivary gland carcinomas, and 1.1 % of parotid gland carcinomas. Here in we aimed to evaluate the clinico-pathological features and treatment outcomes of parotid gland SDC in Saudi population. Among 38...... hiện toàn bộ