Immunohistochemical study of the proliferation modality of synovium in rat adjuvant arthritisJournal of Orthopaedic Science - Tập 8 - Trang 400-407 - 2003
Munetada Kamimoto, Motoshi Kikuchi, Takashi Yashiro, Aki Nihe1, Yusei Kariya, Yuichi Hoshino
To investigate the proliferative potencies of the two types of synovial lining cells (types A and B), we used immunohistochemical techniques under light and electron microscopy to survey the complete process of arthritis in a rat model system. Complete Freund's adjuvant (0.1 ml) containing 5 mg of heat-inactivated Mycobacterium butyricum was administered intradermally into the right hind paws of ...... hiện toàn bộ
BMP-2 and CDMP-2: stimulation of chondrocyte production of proteoglycanJournal of Orthopaedic Science - Tập 8 - Trang 829-835 - 2003
Jun Li, Keun Su Kim, Jin Soo Park, William A. Elmer, William C. Hutton, S. Tim Yoon
A hallmark of intervertebral disc degeneration is loss of proteoglycans. Cytokines may be used to stimulate proteoglycan production in the disc to reverse or prevent disc degeneration. The effects of bone morphogenetic protein 2 (BMP-2) and cartilage-derived morphogenetic protein 2 (CDMP-2) (singly and jointly) on proteoglycan synthesis by a chondrocytic cell line (MC615) were studied. MC615 cells...... hiện toàn bộ