Immunohistochemical study of the proliferation modality of synovium in rat adjuvant arthritisJournal of Orthopaedic Science - Tập 8 - Trang 400-407 - 2003
Munetada Kamimoto, Motoshi Kikuchi, Takashi Yashiro, Aki Nihe1, Yusei Kariya, Yuichi Hoshino
To investigate the proliferative potencies of the two types of synovial lining
cells (types A and B), we used immunohistochemical techniques under light and
electron microscopy to survey the complete process of arthritis in a rat model
system. Complete Freund's adjuvant (0.1 ml) containing 5 mg of heat-inactivated
Mycobacterium butyricum was administered intradermally into the right hind paws
of ... hiện toàn bộ
BMP-2 and CDMP-2: stimulation of chondrocyte production of proteoglycanJournal of Orthopaedic Science - Tập 8 - Trang 829-835 - 2003
Jun Li, Keun Su Kim, Jin Soo Park, William A. Elmer, William C. Hutton, S. Tim Yoon
A hallmark of intervertebral disc degeneration is loss of proteoglycans.
Cytokines may be used to stimulate proteoglycan production in the disc to
reverse or prevent disc degeneration. The effects of bone morphogenetic protein
2 (BMP-2) and cartilage-derived morphogenetic protein 2 (CDMP-2) (singly and
jointly) on proteoglycan synthesis by a chondrocytic cell line (MC615) were
studied. MC615 cells... hiện toàn bộ