Journal of Orthopaedic Research

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Polyethylene wear rate and osteolysis: Critical threshold versus continuous dose-response relationship
Journal of Orthopaedic Research - Tập 23 - Trang 520-525 - 2005
J. Mark Wilkinson, Andrew J. Hamer, Ian Stockley, Richard Eastell
Cellular basis for age-related changes in fracture repair
Journal of Orthopaedic Research - Tập 23 - Trang 1300-1307 - 2005
Chuanyong Lu, Theodore Miclau, Diane Hu, Erik Hansen, Kathy Tsui, Christian Puttlitz, Ralph S. Marcucio
Effects of hydroxyapatite participate debris on the production of cytokines and proteases in human fibroblasts
Journal of Orthopaedic Research - Tập 19 - Trang 621-628 - 2001
James T. Ninomiya, Janine A. Struve, Cary T. Stelloh, Jeffrey M. Toth, Kevin E. Crosby
AbstractCytokines and proteases are secreted by fibroblasts in response to particulate wear debris, and these proteins are felt to play an important role in the development of osteolysis and implant loosening. Although metallic and polyethlyene debris have been studied extensively, little is known about the cellular responses to hydroxyapatite, despite the wide cli...... hiện toàn bộ
Molecular aspects of healing in stabilized and non‐stabilized fractures
Journal of Orthopaedic Research - Tập 19 - Trang 78-84 - 2001
A.X Le, T Miclau, D Hu, J.A Helms
AbstractBone formation is a continuous process that is initiated during fetal development and persists in adults in the form of bone regeneration and remodeling. These latter two aspects of bone formation are clearly influenced by the mechanical environment. In this study we tested the hypothesis that alterations in the mechanical environment regulate the program o...... hiện toàn bộ
Osteon pullout in the equine third metacarpal bone: Effects of ex vivo fatigue
Journal of Orthopaedic Research - Tập 21 - Trang 481-488 - 2003
L.P. Hiller, S.M. Stover, V.A. Gibson, J.C. Gibeling, C.S. Prater, S.J. Hazelwood, O.C. Yeh, R.B. Martin
AbstractAn important concept in bone mechanics is that osteons influence mechanical properties in several ways, including contributing to toughness and fatigue strength by debonding from the interstitial matrix so as to „bridge”︁ developing cracks. Observations of „pulled out„ osteons on fracture surfaces are thought to be indicative of such behavior. We tested the...... hiện toàn bộ
Electromyographic activity of the abdominal and low back musculature during the generation of isometric and dynamic axial trunk torque: Implications for lumbar mechanics
Journal of Orthopaedic Research - Tập 9 Số 1 - Trang 91-103 - 1991
Stuart M. McGill
AbstractThis study focused on the electromyographic activity of the trunk musculature, given the well‐documented link between occupational twisting and the increased incidence of low back pain. Ten men and 15 women volunteered for this study, in which several aspects of muscle activity were examined. The first aspect assessed the myoelectric relationships during is...... hiện toàn bộ
A cumulative damage model for bone fracture
Journal of Orthopaedic Research - Tập 3 Số 1 - Trang 84-90 - 1985
D. R. Carter, William E. Caler
AbstractA mathematical model is presented to describe the combined time‐dependent and cycle‐dependent fracture characteristics of devitalized cortical bone. Failure is interpreted based on a linear‐life fraction rule, which accounts for cumulative creep and fatigue damage under arbitrary loading histories. The model is successful in describing the influence of load...... hiện toàn bộ
Antimicrobial activity of platelet‐leukocyte gel against Staphylococcus aureus
Journal of Orthopaedic Research - Tập 26 Số 3 - Trang 404-410 - 2008
Dirk Jan F Moojen, Peter A. Everts, Rose‐Minke Schure, E.P. Overdevest, André van Zundert, Johannes T. A. Knape, René M. Castelein, Laura B. Creemers, Wouter J.A. Dhert
AbstractPlatelet‐leukocyte gel (PLG) contains high concentrations of platelets and leukocytes. As leukocytes play an important role in the innate host‐defense, we hypothesized that PLG might have antimicrobial properties. This study investigated the antimicrobial activity of PLG against Staphylococcus aureus and the contribution of myelop...... hiện toàn bộ
Neuronal regeneration after application of radiofrequency energy to collagenous tissue is affected by limb immobilization: An in vivo animal study
Journal of Orthopaedic Research - Tập 22 - Trang 1345-1350 - 2004
W. Pötzl, P. Kümpers, T. Szuwart, T. Filler, B. Marquardt, J. Steinbeck
AbstractDespite widespread use of radiofrequency (RF)‐shrinkage, there have been no studies on the influence of RF‐energy on neural elements of collagenous tissue. The purpose of this study was to examine the effect of RF‐shrinkage on neural structures of capsuloligamentous tissue and the recovery of neural elements under different postoperative treatment protocols...... hiện toàn bộ
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