Journal of Neuro-Oncology

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Pleiotrophin expression in astrocytic and oligodendroglial tumors and it’s correlation with histological diagnosis, microvascular density, cellular proliferation and overall survival
Journal of Neuro-Oncology - Tập 84 - Trang 255-261 - 2007
Fernanda M. Peria, Luciano Neder, Sueli K. N. Marie, Sergio Rosemberg, Sueli M. Oba-Shinjo, Benedicto O. Colli, Alberto A. Gabbai, Suzana M. F. Malheiros, Marco A. Zago, Rodrigo A. Panepucci, Carlos A. Moreira-Filho, Oswaldo K. Okamoto, Carlos G. Carlotti
Pleiotrophin (PTN) is a secreted cytokine with several properties related with tumor development, including differentiation, angiogenesis, invasion, apoptosis and metastasis. There is evidence that PTN has also a relevant role in primary brain neoplasms and its inactivation could be important to treatment response. Astrocytic and oligodendroglial tumors are the most frequent primary brain neoplasm...... hiện toàn bộ
Diffuse intrinsic pontine glioma cells are vulnerable to low intensity electric fields delivered by intratumoral modulation therapy
Journal of Neuro-Oncology - Tập 143 - Trang 49-56 - 2019
Andrew Deweyert, Erin Iredale, Hu Xu, Eugene Wong, Susanne Schmid, Matthew O. Hebb
Diffuse intrinsic pontine glioma (DIPG) is a high fatality pediatric brain cancer without effective treatment. The field of electrotherapeutics offers new potential for other forms of glioma but the efficacy of this strategy has not been reported for DIPG. This pilot study evaluated the susceptibility of patient-derived DIPG cells to low intensity electric fields delivered using a developing techn...... hiện toàn bộ
Volume Contents
Journal of Neuro-Oncology - Tập 49 - Trang 269-271 - 2000
Apparent glucose utilization in Walker 256 metastatic brain tumors
Journal of Neuro-Oncology - Tập 3 Số 2 - Trang 153-164 - 1985
Blasberg, Ronald G, Shinohara, Mami, Shapiro, William R., Patlak, Clifford S., Pettigrew, Karen D., Fenstermacher, Joseph D.
Regional rates of apparent glucose utilization (GU) in metastatic Walker 256 (WL-256) brain tumors produced by the intracarotid injection of WL-256 tumor cells in rats were measured using14C-deoxyglucose and quantitative auroradiography. Apparent glucose utilization was uniform within individual small and medium size tumors without necrosis, varied considerably among different tumors within this g...... hiện toàn bộ
Expression of estramustine-binding protein in ependymomas and in human and developing rat ependymal cells
Journal of Neuro-Oncology - Tập 22 - Trang 45-53 - 1994
A. Tommy Bergenheim, Magdalena Hartman, Jonas Bergh, Per -Åke Ridderheim, Roger Henriksson
The mainstays of primary treatment of ependymoma are aggressive surgery followed by radiotherapy. Although spreading occasionally occurs in the cerebrospinal pathways, chemotherapy is still not established and no ultimate drug has so far been found. Estramustine-phosphate (EMP), with a demonstrated effect on astrocytomain vitro, has been shown to penetrate the blood-tumor barrier and to accumulate...... hiện toàn bộ
Two Different Mechanisms of Apoptosis Resistance Observed in Interferon- Induced Apoptosis of Human Glioma Cells
Journal of Neuro-Oncology - Tập 67 Số 3 - Trang 273-280 - 2004
Ryuta Saito, Masaaki Mizuno, Manabu Hatano, Toshihiro Kumabe, Takashi Yoshimoto, Jun Yoshida
Preoperative antiepileptic drug prophylaxis for early postoperative seizures in supratentorial meningioma: a single-center experience
Journal of Neuro-Oncology - Tập 158 - Trang 59-67 - 2022
Qing Cai, Yingxi Wu, Shoujie Wang, Tao Huang, Qilong Tian, Julei Wang, Huaizhou Qin, Dayun Feng
Perioperative antiepileptic drug (AED) prophylaxis for early postoperative seizures (EPSs) in patients with supratentorial meningiomas without preoperative seizures is controversial. This paper discusses the incidence, risk factors, control rate and AED withdrawal indications of EPS in patients undergoing supratentorial convexity and parasagittal/falx meningioma resection without preoperative seiz...... hiện toàn bộ
Intensive chemotherapy followed by reduced-dose radiotherapy for biopsy-proven CNS germinoma with elevated beta-human chorionic gonadotropin
Journal of Neuro-Oncology - Tập 117 Số 2 - Trang 279-285 - 2014
Do Hoon Lim, Keon Hee Yoo, Na Hee Lee, Soo Hyun Lee, Ki Woong Sung, Hong Hoe Koo, Ji Hye Kim, Yeon‐Lim Suh, Yoo Sook Joung, Hyung Jin Shin
The influence of preoperative dependency on mortality, functional recovery and complications after microsurgical resection of intracranial tumors
Journal of Neuro-Oncology - Tập 139 - Trang 441-448 - 2018
Martin N. Stienen, David Y. Zhang, Morgan Broggi, Dominik Seggewiss, Stefano Villa, Silvia Schiavolin, Oliver Bozinov, Niklaus Krayenbühl, Johannes Sarnthein, Paolo Ferroli, Luca Regli
The decision whether to operate on patients with intracranial tumors is complex and influenced by patient-specific factors, including the preoperative functional status. This work assesses the risks for mortality and complications, and post-operative recovery in functionally dependent patients undergoing microsurgical resection of intracranial tumors. Observational two-center study, analyzing inst...... hiện toàn bộ
The treatment of recurrent cerebral gliomas with all-trans-retinoic acid (tretinoin)
Journal of Neuro-Oncology - Tập 34 - Trang 145-151 - 1997
Samer E. Kaba, Athanassios P. Kyritsis, Charles Conrad, Mary Jo Gleason, Robert Newman, Victor A. Levin, W.K. Alfred Yung
Malignant gliomas continue to be a significant sourceof mortality in young and middle aged adults.The introduction of new treatment strategies and multidisciplinaryapproaches has improved the outcome of patients withthese tumors only slightly. Because retinoic acid hasgrowth inhibitory activity against glioma and neuroblastoma cellsin cultures, we assessed the efficacy of all-trans-retinoicacid in...... hiện toàn bộ
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