Journal of Neural Transmission

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The adrenal medulla may mediate the increase in pineal melatonin synthesis induced by stress, but not that caused by exposure to darkness
Journal of Neural Transmission - Tập 40 - Trang 87-97 - 1977
H. J. Lynch, Maria Ho, R. J. Wurtman
As previously shown (Lynch et al.: Proc. Nat. Acad. Sci. [U.S.A.]70, 1704–1707 [1973]), the activity of the enzyme serotonin-N-acetyltransferase (NAT) in the rat pineal increases when the animal is placed in darkness or is subjected to the stress of physical immobilization; partial sympathetic denervation (i.e., pretreatment of the animal with intravenous 6-hydroxydopamine [6-OHDA]) does not block...... hiện toàn bộ
A new quantitative method for evaluating freezing of gait and dual-attention task deficits in Parkinson’s disease
Journal of Neural Transmission - Tập 122 Số 11 - Trang 1523-1531 - 2015
Taylor Chomiak, Fernando Vieira Pereira, Nicole L Meyer, Natalie de Bruin, Lorelei Derwent, Kailie Luan, Alexandra Cihal, Lesley A. Brown, Bin Hu
Morphological basis of Parkinson disease-associated cognitive impairment: an update
Journal of Neural Transmission - Tập 129 - Trang 977-999 - 2022
Kurt A. Jellinger
Cognitive impairment is one of the most salient non-motor symptoms of Parkinson disease (PD) that poses a significant burden on the patients and carers as well as being a risk factor for early mortality. People with PD show a wide spectrum of cognitive dysfunctions ranging from subjective cognitive decline and mild cognitive impairment (MCI) to frank dementia. The mean frequency of PD with MCI (PD...... hiện toàn bộ
Basic cell physiological activities (cell adhesion, chemotaxis and proliferation) induced by selegiline and its derivatives in Mono Mac 6 human monocytes
Journal of Neural Transmission - Tập 119 - Trang 545-556 - 2011
Eszter Lajkó, Lívia Polgár, Orsolya Láng, József Lengyel, László Kőhidai, Kálmán Magyar
Selegiline (R-deprenyl), a monoamine oxidase-B (MAO-B) inhibitor, has complex pharmacological effect that contributes to treatment of neurodegenerative diseases such as Parkinson’s and presumably Alzheimer’s disease and might work as an inhibitor of tumor growth. In respect of tumorigenesis and metastasis formation, the controlled modifications of adhesion and migration have high therapeutic signi...... hiện toàn bộ
Long-term effects of chronic stress models in adult mice
Journal of Neural Transmission - Tập 130 - Trang 1133-1151 - 2023
Inès Tran, Anne-Kathrin Gellner
Neuropsychiatric disorders, such as major depression, anxiety disorders, and post-traumatic stress disorder, tend to be long-term conditions in whose development and maintenance stress are central pathogenic factors. Translational mouse models are widely used in neuropsychiatric research, exploiting social and non-social stressors to investigate the mechanisms underlying their detrimental effects....... hiện toàn bộ
Klinische Untersuchungen der vegetativen Steuerung beim Parkinson-Syndrom postencephalitischer und anderer Ätiologie vor und nach der stereotaktischen Operation
Journal of Neural Transmission - Tập 26 - Trang 552-576 - 1964
W. Umbach, E. W. Fünfgeld
Thermal hypesthesia in patients with complex regional pain syndrome related dystonia
Journal of Neural Transmission - Tập 118 - Trang 599-603 - 2010
Alexander G. Munts, Monique A. van Rijn, Erica J. Geraedts, Jacobus J. van Hilten, J. Gert van Dijk, Johan Marinus
The quantitative thermal test showed cold and warmth hypesthesia without increased heat pain sensitivity in the affected limbs of complex regional pain syndrome (CRPS) patients with tonic dystonia (n = 44) in comparison with healthy controls with a similar age and sex distribution (n = 35). The degrees of cold and warmth hypesthesia were strongly correlated. We conclude that dysfunction in small n...... hiện toàn bộ
Role of glucagon in the control of heat production in ducklings
Journal of Neural Transmission - Tập 113 - Trang 1417-1424 - 2006
A. S. H. Squalli, M. Slimani, Y. Z. Filali, M. N. Benchekroun, S. Elantri, J. L. Rouanet, H. Barre, T. Fechtali
Glucagon is known to be a central modulator of neural activity and a peripheral thermogenic effect. The purpose of this study was to better understand the role of glucagon in the control of heat production, shivering and particularly as a mediator of nonshivering thermogenesis (NST) in ducklings. In order to study the mechanism of NST, an intracerebroventricular (i.c.v.) injection of glucagon (10−...... hiện toàn bộ
Animal models of Parkinson's disease: An empirical comparison with the phenomenology of the disease in man
Journal of Neural Transmission - - 1996
M. Gerlach, P. Riederer
Animal models are an important aid in experimental medical science because they enable one to study the pathogenetic mechanisms and the therapeutic principles of treating the functional disturbances (symptoms) of human diseases. Once the causative mechanism is understood, animal models are also helpful in the development of therapeutic approaches exploiting this understanding. On the basis of expe...... hiện toàn bộ
Sex-differences in catecholamine metabolites in human urine during development and at adulthood
Journal of Neural Transmission - Tập 54 Số 3-4 - Trang 193-207 - 1982
Y. Dalmaz, L Peyrin
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