Novel developments in the pathogenesis and diagnosis of extranodal marginal zone lymphomaJournal of Hematopathology - Tập 10 - Trang 91-107 - 2017
Max I. Schreuder, Michiel van den Brand, Konnie M. Hebeda, Patricia J. T. A. Groenen, J. Han van Krieken, Blanca Scheijen
Extranodal marginal zone lymphoma (EMZL), mostly represented by mucosa-associated lymphoid tissue (MALT) type, also referred to as MALT lymphoma, is a clinically heterogeneous entity within the group of low-grade B cell lymphomas that arises in a wide range of different extranodal sites, including the stomach, lung, ocular adnexa, and skin. It represents the third most common non-Hodgkin lymphoma ...... hiện toàn bộ
Oral follicular lymphoma: a clinicopathologic and molecular studyJournal of Hematopathology - Tập 16 Số 4 - Trang 199-208 - 2023
Lucas Lacerda de Souza, Cínthia Verónica Bardález López de Cáceres, Maria Sissa Pereira Sant’Ana, Paulo Victor Mendes Penafort, Bruno Augusto Benevenuto de Andrade, Hélder Antônio Rebelo Pontes, Wagner Henriques Castro, Ricardo Alves Mesquita, José Cândido Caldeira Xavier‐Júnior, Alan Roger Santos‐Silva, Márcio Ajudarte Lopes, Ciro Dantas Soares, Liam Robinson, W.F.P. Van Heerden, Rommel Rodrı́guez Burbano, Guilherme Rossi Assis‐Mendonça, José Vassallo, Sílvia Ferreira de Sousa, Pablo Agustı́n Vargas, Felipe Paiva Fonseca
Characterization of bone marrow CD4 to CD8 ratios and lymphocyte composition in adults by image analysisJournal of Hematopathology - Tập 14 - Trang 291-298 - 2021
Brian D. Adkins, Nicholas R. Jaeger, Rachel M. Whitehair, Patcharin Pramoonjago, Nadine S. Aguilera
Bone marrow (BM) lymphocyte subsets are evaluated by flow cytometry or immunohistochemistry for diagnostic purposes; however, CD4:CD8 T lymphocyte ratios are often erroneously interpreted using peripheral blood ranges. There are few and no recent studies describing the composition of lymphocytes within the marrow space, or normal reference ranges. Lymphocyte subsets in cytopenic patients and hospi...... hiện toàn bộ
Apoptosis of t(14;18)-positive lymphoma cells by a Bcl-2 interacting small moleculeJournal of Hematopathology - Tập 2 - Trang 113-119 - 2009
David R. Abbott, Robert T. Abbott, Stephen D. Jenson, G. Chris Fillmore, Kojo S. J. Elenitoba-Johnson, Megan S. Lim
Overexpression of Bcl-2 protein occurs via both t(14;18)-dependent and independent mechanisms and contributes to the survival and chemoresistance of non-Hodgkin lymphomas. HA14–1 is a nonpeptidic organic small molecule, which has been shown to inhibit the interaction of Bcl-2 with Bax, thereby interfering with the antiapoptotic function of Bcl-2. In this study, we sought to determine the in vitro ...... hiện toàn bộ
Green inclusions in neutrophils—a case report and review of literatureJournal of Hematopathology - Tập 11 - Trang 1-3 - 2017
Annette Abraham, Claudiu V. Cotta, Alan E. Lichtin
Green refractile inclusions in neutrophils are a very rare peripheral smear finding with few reported cases in literature. They were thought to be a marker of impending death with a very high mortality rate in the immediate hospitalization period. They were often seen in critically ill patients and often related to liver injury. Clinical and pathophysiologic characterizations of these inclusions a...... hiện toàn bộ
B-lymphoblastic leukemia/lymphoma with MYC and BCL2 gene rearrangements shows evidence for clonal evolution and mitotic recombinationJournal of Hematopathology - Tập 16 - Trang 111-117 - 2023
Steven A. Schichman, Andrea L. Penton, Sai Nikhila Ghanta, Manojna Konda, Peter R. Papenhausen
B-lymphoblastic leukemia/lymphomas (B-ALL/LBL) are uncommon neoplasms that may be associated with a variety of cytogenetic and molecular changes. The mechanisms by which these changes arise have not been fully described. This report describes an unusual case of B-ALL/LBL with complex clonal evolution that includes BCL2 and MYC gene rearrangements. Immunophenotyping was performed by immunohistochem...... hiện toàn bộ