Journal of Biological Physics

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A DNA-based in vitroGenetic Program
Journal of Biological Physics - Tập 28 - Trang 493-498 - 2002
J.A. Rose, M. Hagiya, R.J. Deaton, A. Suyama
In PNA-mediated Whiplash PCR (PWPCR), autonomous molecular computation is implemented by the recursive polymerase extension of a mixture of DNA hairpins. Like other methods based on exhaustive search, however, application to problem instances of realistic size is prevented by the exponential scaling of thesolution space. The tendency of evolving populations to minimize the sampling of large, low f...... hiện toàn bộ
Stepwise oscillatory circuits of a DNA molecule
Journal of Biological Physics - Tập 35 - Trang 223-230 - 2009
Kunming Xu
A DNA molecule is characterized by a stepwise oscillatory circuit where every base pair is a capacitor, every phosphate bridge is an inductance, and every deoxyribose is a charge router. The circuitry accounts for DNA conductivity through both short and long distances in good agreement with experimental evidence that has led to the identification of the so-called super-exchange and multiple-step h...... hiện toàn bộ
Biochemical oscillations and the development of organization
Journal of Biological Physics - Tập 10 - Trang 111-112 - 1982
Electrostatic potential comparison and molecular metric spaces
Journal of Biological Physics - - 1986
Ramon Carbot, Eduard Suñe, Felix Lapeña, Jose Perez
A possible definition of a metric associated with a set of electrostatic molecular potentials is analyzed. Examples of its application to formaldehyde and analogous structures, and to MAO substrates are presented.
Enumerating Designing Sequences in the HP Model
Journal of Biological Physics - Tập 28 - Trang 1-15 - 2002
Anders Irbäck, Carl Troein
The hydrophobic/polar HP model on the square lattice has been widely used toinvestigate basics of protein folding. In the cases where all designing sequences (sequences with unique ground states) were enumerated without restrictions on the number of contacts, the upper limit on the chain length N has been 18–20 because of the rapid exponential growth of thenumbers of conformations and sequences. W...... hiện toàn bộ
Dynamics of the Subthalamo-pallidal Complex in Parkinson’s Disease During Deep Brain Stimulation
Journal of Biological Physics - Tập 34 - Trang 251-266 - 2008
J. Modolo, J. Henry, A. Beuter
The dynamics of the subthalamo-pallidal complex in Parkinson’s disease during deep brain stimulation (DBS) were studied using two models, a simple firing-rate model and a population-based model. We extended the simple firing-rate model of the complex formed by the subthalamic nucleus (STN) and the external segment of the Globus Pallidus (GPe) to explore its dynamical regime during DBS. More specif...... hiện toàn bộ
Supersonic Vibron Solitons and Their Possible Existence in Polypeptides
Journal of Biological Physics - Tập 24 - Trang 185-199 - 1999
Shozo Takeno
Nonlinear interactions of vibrons with lattice solitons due to the soft cubic nonlinearity in a quasi-one-dimensional lattice yield supersonic vibron solitons. Their binding energy is larger than those of the conventional Davydov solitons and vibron solitons, and their propagation velocity is uniquely determined in contrast to the latter two. Examination of parameters in the model Hamiltonian for ...... hiện toàn bộ
Quantification of adaptive forces on SNP rs1010211 due to viral zoonotic pathogens
Journal of Biological Physics - - 2022
Daniah Alsufyani, James Lindesay
AbstractWidespread genotyping of human populations in environmental homeostasis has created opportunities to quantify how environmental parameters affect the genomic distribution of variants in healthy populations. This represents an ongoing natural experiment upon the human species that can only be understood through developing models of adaptation. By examining t...... hiện toàn bộ
Red Blood Cell Shape and Fluctuations: Cytoskeleton Confinement and ATP Activity
Journal of Biological Physics - Tập 31 - Trang 453-464 - 2005
N. Gov, S. A. Safran
We review recent theoretical work that analyzes experimental measurements of the shape and fluctuations of red blood cells. Particular emphasis is placed on the role of the cytoskeleton and cell elasticity and we contrast the situation of elastic cells with that of fluid-filled vesicles. In red blood cells (RBCs), the cytoskeleton consists of a two-dimensional network of spectrin proteins. Our ana...... hiện toàn bộ
A Novel Phase-contrast Transmission Electron Microscopy Producing High-contrast Topographic Images of Weak objects
Journal of Biological Physics - Tập 28 - Trang 627-635 - 2002
R. Danev, H. Okawara, N. Usuda, K. Kametani, K. Nagayama
We report a novel class of transmission electron microscope (TEM), the difference-contrast electron microscope (DTEM), which displays nanostructures of thin specimen objects in a topographical manner. Topography obtained by the difference-contrast develops shadowgraphs in pseudo three-dimension, namely volume-like representation of projected objects as if things are illuminated by light from one d...... hiện toàn bộ
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