Journal of Biological Engineering
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Surface modification of decellularized bovine carotid arteries with human vascular cells significantly reduces their thrombogenicity
Journal of Biological Engineering - Tập 15 - Trang 1-20 - 2021
Since autologous veins are unavailable when needed in more than 20% of cases in vascular surgery, the production of personalized biological vascular grafts for implantation has become crucial. Surface modification of decellularized xenogeneic grafts with vascular cells to achieve physiological luminal coverage and eventually thromboresistance is an important prerequisite for implantation. However,......
RSM based optimization of nutritional conditions for cellulase mediated Saccharification by Bacillus cereus
Journal of Biological Engineering - Tập 12 - Trang 1-10 - 2018
Cellulases are enzyme which have potential applications in various industries. Researchers are looking for potential cellulolytic bacterial strains for industrial exploitation. In this investigation, cellulase production of Bacillus cereus was explored while attacking poplar twigs. The bacterium was isolated from the gut of freshwater fish, Labeo rohita and identified by 16S rRNA gene sequencing t......
Discrimination between the effects of pulsed electrical stimulation and electrochemically conditioned medium on human osteoblasts
Journal of Biological Engineering - Tập 17 - Trang 1-18 - 2023
Electrical stimulation is used for enhanced bone fracture healing. Electrochemical processes occur during the electrical stimulation at the electrodes and influence cellular reactions. Our approach aimed to distinguish between electrochemical and electric field effects on osteoblast-like MG-63 cells. We applied 20 Hz biphasic pulses via platinum electrodes for 2 h. The electrical stimulation of th......
Advances in the application of Mxene nanoparticles in wound healingAbstract Skin is the largest organ of the human body. It plays a vital role as the body’s first barrier: stopping chemical, radiological damage and microbial invasion. The importance of skin to the human body can never be overstated. Delayed wound healing after a skin injury has become a huge challenge in healthcare. In some situations, this can have very serious an... ...
Journal of Biological Engineering - Tập 17 Số 1
The LINC complex, mechanotransduction, and mesenchymal stem cell function and fate
Journal of Biological Engineering - Tập 13 - Trang 1-12 - 2019
Mesenchymal stem cells (MSCs) show tremendous promise as a cell source for tissue engineering and regenerative medicine, and are understood to be mechanosensitive to external mechanical environments. In recent years, increasing evidence points to nuclear envelope proteins as a key player in sensing and relaying mechanical signals in MSCs to modulate cellular form, function, and differentiation. Of......
Formaldehyde formation in the glycine cleavage system and its use for an aldolase-based biosynthesis of 1,3-propanediolAbstract Glycine cleavage system (GCS) occupies a key position in one-carbon (C1) metabolic pathway and receives great attention for the use of C1 carbons like formate and CO2 via synthetic biology. In this work, we demonstrate that formaldehyde exists as a substantial byproduct of the GCS reaction cycle. Three causes are identified for its form... ...
Journal of Biological Engineering - - 2020
Label-free electrochemical sensor to investigate the effect of tocopherol on generation of superoxide ions following UV irradiation
Journal of Biological Engineering - Tập 12 - Trang 1-10 - 2018
Generation of reactive oxygen species (ROS), triggered by ultraviolet radiation (UVR), is associated with carcinogenesis of the skin. UV irradiation induced superoxide anion (O2•−) is the key ROS involved in the cellular damage. The cytoprotective efficacy of an unknown anti-oxidant compound can be evaluated by analyzing the production of O2•− from treated cells. In this study, a glass carbon elec......
In vivo analysis of fracture toughness of thyroid gland tumors
Journal of Biological Engineering - Tập 2 Số 1 - Trang 12 - 2008
A multiplexed magnetic tweezer with precision particle tracking and bi-directional force control
Journal of Biological Engineering - Tập 11 - Trang 1-13 - 2017
In the past two decades, methods have been developed to measure the mechanical properties of single biomolecules. One of these methods, Magnetic tweezers, is amenable to acquisition of data on many single molecules simultaneously, but to take full advantage of this "multiplexing" ability, it is necessary to simultaneously incorporate many capabilities that have been only demonstrated separately. O......
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