Journal of Biological Engineering
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Optimization of the fermentation process of Cordyceps sobolifera Se-CEPS and its anti-tumor activity in vivo
Journal of Biological Engineering - Tập 10 - Trang 1-9 - 2016
Cordyceps sobolifera (C. sobolifera) isolated from cicadae was used as the starting fungus to produce selenium-enriched C. sobolifera extracellular polysaccharide (Se-CEPS). An orthogonal experimental design based on a single-factor experiment was used to optimize the C. sobolifera fermentation conditions, including the potato juice, peptone, and KH2PO4 concentrations. ...... hiện toàn bộ
Mixture theory modeling for characterizing solute transport in breast tumor tissues
Journal of Biological Engineering - Tập 13 - Trang 1-16 - 2019
Tumor numerical models have been used to quantify solute transport with a single capillary embedded in an infinite tumor expanse, but measurements from different mammalian tumors suggest that a tissue containing a single capillary with an infinite intercapillary distance assumption is not physiological. The present study aims to investigate the limits of the intercapillary distance within which na...... hiện toàn bộ
Rise of the killer plants: investigating the antimicrobial activity of Australian plants to enhance biofilter-mediated pathogen removal
Journal of Biological Engineering - Tập 13 - Trang 1-14 - 2019
Biofilters are soil-plant based passive stormwater treatment systems which demonstrate promising, although inconsistent, removal of faecal microorganisms. Antimicrobial-producing plants represent a safe, inexpensive yet under-researched biofilter design component that may enhance treatment reliability. The mechanisms underlying plant-mediated microbial removal in biofilters have not been fully elu...... hiện toàn bộ
Incorporating immersive learning into biomedical engineering laboratories using virtual reality
Journal of Biological Engineering - Tập 16 Số 1 - Trang 1-11 - 2022
The Covid-19 pandemic caused a sudden shift towards remote learning, moving classes to online formats. Not exempt from this switch, laboratory courses traditionally taught in-person were also moved to remote methods, costing students the opportunity to learn these skills hands-on. In order for instructors to provide course materials effectively and engagingly, non-traditional methods should be exp...... hiện toàn bộ
Environment-sensitive behavior of fluorescent molecular rotors
Journal of Biological Engineering - Tập 4 - Trang 1-14 - 2010
Molecular rotors are a group of fluorescent molecules that form twisted intramolecular charge transfer (TICT) states upon photoexcitation. When intramolecular twisting occurs, the molecular rotor returns to the ground state either by emission of a red-shifted emission band or by nonradiative relaxation. The emission properties are strongly solvent-dependent, and the solvent viscosity is the primar...... hiện toàn bộ
Synthesis of control unit for future biocomputer
Journal of Biological Engineering - Tập 12 - Trang 1-16 - 2018
Synthesis of a variety of biological circuits for specific functional purposes has made a tremendous progress in recent years. The ultimate goal of combining molecular biology and engineering is to realize a functional biocomputer. To address this challenge, all previous efforts work toward building up the bio-computer as the ultimate goal. To this aim, there should be a key module, named control ...... hiện toàn bộ
Insights into the mechanism of a novel shockwave-assisted needle-free drug delivery device driven by in situ-generated oxyhydrogen mixture which provides efficient protection against mycobacterial infections
Journal of Biological Engineering - Tập 11 - Trang 1-13 - 2017
Needle-free, painless and localized drug delivery has been a coveted technology in the area of biomedical research. We present an innovative way of trans-dermal vaccine delivery using a miniature detonation-driven shock tube device. This device utilizes~2.5 bar of in situ generated oxyhydrogen mixture to produce a strong shockwave that accelerates liquid jets to velocities of about 94 m/s. Oxyhydr...... hiện toàn bộ
The role of fibroblast growth factor 1 and 2 on the pathological behavior of valve interstitial cells in a three-dimensional mechanically-conditioned model
Journal of Biological Engineering - - 2019
More than five million Americans suffer from heart valve disease annually, a condition that worsens cardiac function and gradually leads to heart failure if appropriate treatment is not performed on time. Currently no medication can cure heart valve disease, leaving surgical intervention as the only viable option for patients at late stages of cardiac valve disease. Tremendous efforts have been un...... hiện toàn bộ
Cross-section perimeter is a suitable parameter to describe the effects of different baffle geometries in shaken microtiter plates
Journal of Biological Engineering - Tập 8 - Trang 1-10 - 2014
Biotechnological screening processes are performed since more than 8 decades in small scale shaken bioreactors like shake flasks or microtiter plates. One of the major issues of such reactors is the sufficient oxygen supply of suspended microorganisms. Oxygen transfer into the bulk liquid can in general be increased by introducing suitable baffles at the reactor wall. However, a comprehensive and ...... hiện toàn bộ
A positive feedback-based gene circuit to increase the production of a membrane protein
Journal of Biological Engineering - Tập 4 - Trang 1-7 - 2010
Membrane proteins are an important class of proteins, playing a key role in many biological processes, and are a promising target in pharmaceutical development. However, membrane proteins are often difficult to produce in large quantities for the purpose of crystallographic or biochemical analyses. In this paper, we demonstrate that synthetic gene circuits designed specifically to overexpress cert...... hiện toàn bộ
Tổng số: 394
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