Journal of Analysis and Testing

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An Alternative Low-Cost Strategy for Simultaneous Sensitive Detection of Adjacent ESR1 Mutations in Single Circulating Tumor Cell
Journal of Analysis and Testing - Tập 7 - Trang 89-100 - 2022
Chen Wang, Jing-Jie Wang, Xi-Ru Xue, Yi-Yun Shen, Bing-Jie Zou, Shao-Hua Wang, Qin-Xin Song, Guo-Hua Zhou
ESR1 mutation is of great clinical significance and being promoted as a marker of resistance to endocrine therapy in breast cancers. However, it is a challenging task to detect ESR1 mutations from traditional biopsies and cell-free DNA (cfDNA), especially for polyclonal mutations. This is mainly attributed to massive wild-type background and the low-abundance of the mutations. Here, using one-step...... hiện toàn bộ
Chemoselective Probes Serving as Promising Derivatization Tools in Targeted Metabolomics Research
Journal of Analysis and Testing - Tập 4 Số 3 - Trang 175-182 - 2020
Jie Chen, Yuan Tian, Yuxin Zhang, Fengguo Xu
Visible Light Responsive DNA Thermotropic Liquid Crystals Based on a Photothermal Effect of Gold Nanoparticles
Journal of Analysis and Testing - Tập 5 - Trang 181-187 - 2021
Lei Zhang, Yang Qu, Yun Liu, Yawen Deng, Jingjing Gu, Zhongtao Wu, Jiehua Lin, Xiliang Luo
Solvent free DNA–surfactant melts are receiving continuous attractions in recent years. Their physical properties could be regulated via changing the alkyl chain length of surfactants. As an ideal external stimulus, light has been used in the regulation of mechanical properties of DNA thermotropic liquid crystal (TLC) containing an azobenzene motif, while in this case, the UV light is the only eff...... hiện toàn bộ
Correction to: Metabolomic Fingerprinting of Blood Samples by Direct Infusion Mass Spectrometry: Application in Alzheimer’s Disease Research
Journal of Analysis and Testing - Tập 1 - Trang 213-222 - 2017
Raúl González-Domínguez
Correction to: J. Anal. Test. (2017) 1:17 DOI 10.1007/s41664-017-0018-4.
Challenging Nanopores with Analyte Scope and Environment
Journal of Analysis and Testing - Tập 3 - Trang 61-79 - 2019
Buddini I. Karawdeniya, Y. M. Nuwan D. Y. Bandara, Jonathan W. Nichols, Robert B. Chevalier, James T. Hagan, Jason R. Dwyer
Nanopores are nanofluidic channels formed through thin membranes that can deliver standout single-molecule and single-particle sensing capabilities. Analytical targets include small molecules and nanoparticles, and the DNA, protein, and glycan biopolymers underpinning genomics, proteomics, and glycomics. Detection—notably even in the simplest implementation, resistive-pulse sensing—does not inhere...... hiện toàn bộ
Recent Advances in Visual Electrochemiluminescence Analysis
Journal of Analysis and Testing - Tập 4 - Trang 92-106 - 2020
Qian Zhang, Xin Zhang, Qiang Ma
Due to the advantages of low background interference and high sensitivity, electrochemiluminescence (ECL)-based sensor has developed rapidly in recent years. The ECL sensors have shown the potential in the ultrasensitive and real-time analysis. Especially, the visual ECL analysis, including visual detection, cell imaging and single particle analysis, has offered many unique sensing platforms for a...... hiện toàn bộ
Determination of Aroclor 1254 in Water Samples Using Polystyrene–Divinylbenzene Solid-Phase Extraction and Gas Chromatography
Journal of Analysis and Testing - Tập 2 - Trang 306-311 - 2018
Fei Shen, Yan-Juan Xu, Ye Wang, Pei-Yu Zhu, Xiu-Li Dai, Jing Chen, Qian Zou
A method was developed for the determination of Aroclor 1254 in water samples using polystyrene–divinylbenzene (PS–DVB) solid-phase extraction (SPE) and gas chromatography (GC). The PS–DVB sorbent demonstrated good recoveries of Aroclor 1254 when sulfuric acid (1:1, v:v) was added to the samples. Sample quantification was performed using gas chromatography with a parallel column and dual electron ...... hiện toàn bộ
Salting-out Assisted Liquid–Liquid Extraction for Analysis of Caffeine and Nicotinic Acid in Coffee by HPLC–UV/Vis Detector
Journal of Analysis and Testing - Tập 4 - Trang 298-306 - 2020
Gadisa Chirfa, Yared Merdassa, Abera Gure
A salting-out assisted liquid–liquid extraction method followed by high performance liquid chromatography with ultraviolet–visible detector (SALLE-HPLC–UV/Vis) has been proposed for determination of caffeine and nicotinic acid in raw and roasted coffee samples. Various parameters affecting chromatographic separations including mobile phase composition, injection volume, flow rate and column temper...... hiện toàn bộ
Untargeted LC–MS Data Preprocessing in Metabolomics
Journal of Analysis and Testing - Tập 1 - Trang 187-192 - 2017
He Tian, Bowen Li, Guanghou Shui
Liquid chromatography–mass spectrometry (LC–MS) has enabled the detection of thousands of metabolite features from a single biological sample that produces large and complex datasets. One of the key issues in LC–MS-based metabolomics is comprehensive and accurate analysis of enormous amount of data. Many free data preprocessing tools, such as XCMS, MZmine, MAVEN, and MetaboAnalyst, as well as comm...... hiện toàn bộ
Recent Advances on Chiral Mobile Phase Additives: A Critical Review
Journal of Analysis and Testing - Tập 6 - Trang 129-162 - 2022
Yuan Li, Xiao-Ning Jin, Yue Cheng, Xiao-Fei Ma, Yong Wang
Chirality is one of the fundamental attributes of nature, which exists in different or even completely opposite metabolic, toxicological and pharmacological properties in organisms. Consequently, obtaining enantiomerically pure drugs or optically active intermediates is highly desired in many fields like medicine, food and biochemistry. Thereby, it also promoted the development of various enantiom...... hiện toàn bộ
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