Italian Journal of Pediatrics
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Metabolic syndrome: new therapeutic approaches
Italian Journal of Pediatrics - Tập 40 - Trang 1-2 - 2014
Thyroid function test evolution in children with Hashimoto’s thyroiditis is closely conditioned by the biochemical picture at diagnosis
Italian Journal of Pediatrics - Tập 44 - Trang 1-6 - 2018
Aim of this commentary is to summarize the salient literature views on the relationships between presentation and evolution patterns of thyroid function in children with Hashimoto’s thyroiditis (HT). According to the most recent reports, children with HT and subclinical hypothyroidism (SH) are more prone to the risk of developing severe thyroid dysfunctions over time, if compared to those presenti......
Biochemical and molecular analysis in mucopolysaccharidoses: what a paediatrician must know
Italian Journal of Pediatrics - Tập 44 - Trang 35-45 - 2018
Mucopolysaccharidoses (MPS) are rare inherited disorders caused by a deficit of the lysosomal hydrolases involved in the degradation of mucopolysaccharides, also known as glycosaminoglycans (GAGs). They are all monogenic defects, transmitted in an autosomal recessive way, except for MPS type II which is X-linked. The enzymatic deficit causes a pathologic accumulation of undegraded or partially deg......
Issues of vaccination in premature infants: an overview
Italian Journal of Pediatrics - Tập 41 - Trang 1-2 - 2015
Recurrent upper respiratory tract infections in early childhood: a newly defined clinical condition
Italian Journal of Pediatrics - Tập 50 - Trang 1-5 - 2024
Recurrent Upper Respiratory Tract Infections (R-URTIs) pose a significant challenge in pediatric healthcare, affecting both children and their families. This study aimed to investigate the prevalence, risk factors, and clinical implications of R-URTI in children aged 0–5 years. This observational study involved a sample of 483 children aged 0–5 years, focusing on establishing a practical and dynam......
Replicative verification of susceptibility genes previously identified from families with segregating developmental dysplasia of the hip
Italian Journal of Pediatrics - - 2021
Developmental dysplasia of the hip (DDH) is a complex hip joint deformity with effects ranging from acetabulum malformation to irreversible hip dislocation. Previous studies suggest a significant association of four variations, teneurin transmembrane protein 3 (TENM3, OMIM * 610083) (chr4:183721398), heparan sulfate proteoglycan 2 (HSPG2, OMIM * 142461) (chr1:22201470), ATPase plasma membrane Ca2+......
Molecular physiopathogenetic mechanisms and development of new potential therapeutic strategies in persistent pulmonary hypertension of the newborn
Italian Journal of Pediatrics - Tập 41 - Trang 1-11 - 2015
Persistent pulmonary hypertension of the newborn (PPHN) is a cyanogenic plurifactorial disorder characterized by failed postnatal drop of pulmonary vascular resistance and maintenance of right-to-left shunt across ductus arteriosus and foramen ovale typical of intrauterine life. The pathogenesis of PPHN is very complex and can result from functional (vasoconstriction) or structural (arteriolar rem......
The effect of educational intervention based on BASNEF model for reducing internet addiction among female students: a quasi-experimental studyAbstract
Background
Adolescents and students are encountered with a challenge so-called “internet Addiction”. This issue affects both their physical and mental health, as well as their academic, social, and family performance. The aim of the current research is to determine the impact of educational intervention. To achieve this a... ...
Italian Journal of Pediatrics - - 2019
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