Italian Journal of Pediatrics
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Utility of a pediatric observation unit for the management of children admitted to the emergency departmentAbstract
Background
Observation Units (OU), as part of emergency department (ED), are areas reserved for short-term treatment or observation of patients with selected diagnoses to determine the need for hospitalization or home referral.
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Italian Journal of Pediatrics - - 2021
Microbiota biodiversity in inflammatory bowel disease
Italian Journal of Pediatrics - Tập 40 - Trang 1-6 - 2014
Gut microbiota plays a significant role in human health and energy balance, and provides protection against disease states. An altered balance between microbiota and its host (dysbiosis) would appear to contribute to the development of Inflammatory Bowel Disease (IBD), Crohn’s Disease (CD) and Ulcerative Colitis (UC). CD and UC are chronic inflammatory diseases of the gastrointestinal tes.
Acute post-infectious cerebellar ataxia due to co-infection of human herpesvirus-6 and adenovirus mimicking myositis
Italian Journal of Pediatrics - Tập 40 - Trang 1-3 - 2014
Acute cerebellar ataxia (ACA) is a relatively common neurological disease in children. Most common types of ACA are acute post-infectious (APCA) and acute disseminated encephalomyelitis (ADEM). Less common but important causes include opsoclonus-myoclonus syndrome (OMS) and acute cerebellitis. Cerebellar neoplasms and acute hydrocephalus are additional causes of paediatric ataxia. APCA is the most...... hiện toàn bộ
NKX2.1-Related Disorders: a novel mutation with mild clinical presentation
Italian Journal of Pediatrics - Tập 41 - Trang 1-5 - 2015
A highly variable phenotype characterized by thyroid, respiratory and neurological defects has been reported in an already established group of disorders namely NKX2.1-related disorders. We describe here the case of an infant with a novel mutation of the NKX2.1 gene characterized by mild clinical presentation. Aim of the study was to elucidate the genotype-phenotype correlation in our patient. We ...... hiện toàn bộ
Sedentary behaviour as a risk factor for cardiovascular diseases in pediatric age
Italian Journal of Pediatrics - Tập 40 - Trang 1-1 - 2014
Prognostic factors and predictors of outcome in children with autism spectrum disorder: the role of the paediatrician
Italian Journal of Pediatrics - Tập 47 - Trang 1-12 - 2021
Autism spectrum disorder is a complex condition with wide variation in type and severity that involves persistent challenges in social interaction, speech and nonverbal communication, restricted/repetitive behaviours and adaptive behaviours. In recent years, research has deepened the study of the predictive factors of optimal outcome, intended as indicators of positive trajectory in children with ...... hiện toàn bộ
Prophylaxis protects infants with congenital heart disease from severe forms of RSV infection: an Italian observational retrospective study
Italian Journal of Pediatrics - Tập 49 Số 1 - Trang 1-7 - 2023
In children with congenital heart disease (CHD) respiratory syncytial virus (RSV) infection may have a severe course, with increased risk of morbidity and mortality, requiring hospital admission and intensive care. The aim of the present study was to evaluate the effect of prophylaxis with palivizumab in preventing RSV-associated hospitalization in infants with CHD. We carried out an observational...... hiện toàn bộ
Novel SCNN1A gene splicing-site mutation causing autosomal recessive pseudohypoaldosteronism type 1 (PHA1) in two Italian patients belonging to the same small town
Italian Journal of Pediatrics - Tập 47 - Trang 1-6 - 2021
Pseudohypoaldosteronism type 1 (PHA1) is a rare genetic disease due to the peripheral resistance to aldosterone. Its clinical spectrum includes neonatal salt loss syndrome with hyponatremia and hypochloraemia, hyperkalemia, metabolic acidosis and increased plasmatic levels of aldosterone. Two genetically distinct forms of disease, renal and systemic, have been described, showing a wide clinical ex...... hiện toàn bộ
Globalization of pediatric research: pharmacological RCTs in Latin America
Italian Journal of Pediatrics - Tập 45 - Trang 1-4 - 2019
Globalization caused a shift in trial locations towards low-middle income countries, raising ethical concerns. These include the risk that conditions primarily affecting children in these countries will be neglected in favor of those affecting developed countries. We analyzed 253 published and 69 ongoing pharmacological RCTs performed in Latin America between 2000 and 2015 involving exclusively ch...... hiện toàn bộ
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