Microsphere distribution in the pancreas of anesthetized ratsInternational Journal of Pancreatology - Tập 20 - Trang 69-74 - 1996
Leif Jansson
Islet blood flow stimulation induced by alloxan leads to an increased blood perfusion in all islets, whereas glucose induces a flow increase only in a subgroup of islets. The aim of the present study was to investigate if an increased islet blood flow was associated with an enhanced total number of perfused islets, or whether only a subgroup of the islets increased their blood flow. For this purpo...... hiện toàn bộ
A specific and sensitive radioimmunoassay for rat C-peptideInternational Journal of Pancreatology - Tập 13 - Trang 87-95 - 1993
Jones O. Akpan, Lamont G. Weide, Ronald L. Gingerich
A sensitive and specific radioimmunoassay for rat serum C-peptide (RCP) has been developed and validated using a guinea pig anti-rat C-peptide antibody to synthetic rat C-peptide. Negligible crossreactivity (<0.01%) to human proinsulin was observed, whereas human insulin, human pancreatic polypeptide (hPP), porcine insulin, porcine C-peptide, bovine insulin, rat insulin, porcine-PP, and glucagon, ...... hiện toàn bộ
Bifid pancreasInternational Journal of Pancreatology - - 1994
V. S. R. Krishnamurty, Suresh Rajendran, Mark A. Korsten
Atypical acinar cell foci in human pancreasInternational Journal of Pancreatology - Tập 22 - Trang 127-130 - 1997
Juneming Fang, Jerry Hussong, B. D. Roebuck, Mark S. Talamonti, M. Sambasiva Rao
The morphological and quantitative findings of the present study suggest that atypical acinar cell foci are not neoplastic in nature. Atypical acinar cell foci (AACF) are rare and unusual lesions in the human pancreas. The biological nature of AACF is poorly understood, and is not clear whether they represent neoplastic or degenerative changes in the acinar cells. To further characterize and under...... hiện toàn bộ
Protective effect of 4-hydroxy-TEMPO, a low molecular weight superoxide dismutase mimic, on free radical toxicity in experimental pancreatitisInternational Journal of Pancreatology - Tập 18 Số 2 - Trang 153-160 - 1995
Zbigniew Śledziński, Michał Wożniak, J⊹drzej Antosiewicz, Emanuele Lezoche, Massimo Familiari, Enrico Bertoli, Lucedio Greci, Alessandro Brunelli, Nino Mazera, Z Wajda
Radiation therapy and 5-fluorouracil modulated by leucovorin for adenocarcinoma of the pancreasInternational Journal of Pancreatology - Tập 12 - Trang 239-243 - 1992
David J. Schifeling, Andre A. Konski, John M. Howard, Ralph R. Dobelhower, Hollis W. Merrick, Roland T. Skeel
This Phase I study was designed to build on the Gastrointestinal Tumor Study Group’s experience with combined modality therapy in patients with pancreatic cancer. Thirteen patients with adenocarcinoma of the pancreas received weekly 5-fluorouracil by rapid intravenous infusion midway through a 2-h infusion of high dose leucovorin during external beam radiation therapy. Twelve patients received 100...... hiện toàn bộ
Oral pancreatic enzyme therapy in the control of diabetes mellitus in tropical calculous pancreatitisInternational Journal of Pancreatology - Tập 24 - Trang 19-22 - 1998
V. Mohan, S. Poongothai, C. S. Pitchumoni
Pancreatic enzyme supplementation therapy conducted during a 6 moperiod produces better control of diabetes, improvement in nutrition, and overall improvement in quality of life in patients with tropical calculous pancreatitis. Tropical calculous pancreatitis is characterized by abdominal pain, pancreatic calculi, and diabetes. The diabetes is insulin resistant. The brittle diab...... hiện toàn bộ
Long-term effect of growth promoting conditions on the exocrine pancreas of ratsInternational Journal of Pancreatology - Tập 5 - Trang 55-67 - 1989
Bernd Glasbrenner, Peter Malfertheiner, Markus Büchler, Friedrich Brändle, Helmut Friess, Hans Ditschuneit
Pancreatic adaptation following prolonged exposition to growth promoting conditions (protease inhibitor feeding, B II subtotal gastrectomy, subtotal colectomy) was studied in rats. Fifty male Wistar rats were divided into 5 groups: controls (n = 10), sham-operated (n = 10), low dose protease inhibitor feeding (n = 10), B II subtotal gastrectomy (n = 10), and subtotal colectomy (n = 10). After 4 mo...... hiện toàn bộ
Effect of protease inhibitors on peptide-stimulated amylase secretion from dispersed pancreatic aciniInternational Journal of Pancreatology - Tập 17 - Trang 261-269 - 1995
Qiming J. Wang, Thomas E. Adrian
Cholecystokinin (CCK) and bombesin stimulate dose-dependent amylase secretion from dispersed pancreatic acini. To establish whether cellular proteases can reduce secretion by degrading these regulatory peptides, the effect of protease inhibition on CCK and bombesin stimulated amylase secretion was investigated. A spectrum of protease inhibitors, including bacitracin, phenylmethylsulfonylfluoride, ...... hiện toàn bộ