The Use of “Optimal Cytoreduction” Nomenclature in Ovarian Cancer Literature: Can We Move Toward a More Optimal Classification System?International Journal of Gynecological Cancer - Tập 26 Số 8 - Trang 1421-1427 - 2016
Ana M. Angarita, Rebecca L. Stone, Sarah M. Temkin, Kimberly Levinson, Amanda N. Fader, Edward J. Tanner
ObjectivesThe objective of this study is to explore how cytoreductive surgical
outcomes such as residual disease (RD) and use of the term “optimal
cytoreduction” (OCR) have changed over time in the ovarian cancer
literature.MethodsWe identified all English-language publications referring to
ovarian cancer cytoreduction for a 12-year period. Publications were evaluated
for how the diameter of RD wa... hiện toàn bộ
Long-Term Oncologic and Reproductive Outcomes in Young Women With Early Endometrial Cancer Conservatively Treated: A Prospective Study and Literature UpdateInternational Journal of Gynecological Cancer - Tập 26 Số 9 - Trang 1650-1657 - 2016
Giuseppe Laurelli, Francesca Falcone, Maria Stella Gallo, Felice Scala, Simona Losito, Vincenza Granata, Marco Cascella, Stefano Greggi
ObjectiveThis study aimed to analyze the long-term oncologic and reproductive
outcomes in endometrial cancer (EC) in young patients conservatively treated by
combined hysteroscopic resection (HR) and levonorgestrel intrauterine device
(LNG-IUD).MethodsTwenty-one patients (age ≤ 40 years; Stage IA, G1-2
endometrioid EC), wishing to preserve their fertility, were enrolled into this
prospective study... hiện toàn bộ
Combined Oral Medroxyprogesterone/Levonorgestrel-Intrauterine System Treatment for Women With Grade 2 Stage IA Endometrial CancerInternational Journal of Gynecological Cancer - Tập 27 Số 4 - Trang 738-742 - 2017
Ji Young Hwang, Da Hee Kim, Hyo Sook Bae, Mi‐La Kim, Yong Wook Jung, Bo Seong Yun, Seok Ju Seong, Eunah Shin, Mi Kyoung Kim
ObjectiveThe aim of this study was to evaluate the oncologic and pregnancy
outcomes of combined oral medroxyprogesterone acetate
(MPA)/levonorgestrel-intrauterine system (LNG-IUS) treatment in young women with
grade 2–differentiated stage IA endometrial adenocarcinoma who wish to preserve
fertility.MethodsWe retrospectively reviewed the medical records of patients
with grade 2 stage IA endometrial... hiện toàn bộ
First-Line Therapy in Ovarian Cancer TrialsInternational Journal of Gynecological Cancer - Tập 21 Số 4 - Trang 756-762 - 2011
Tate Thigpen, Andreas duBois, Jessica N. McAlpine, Philip J. DiSaia, Keiichi Fujiwara, William J. Hoskins, Gunnar B. Kristensen, Robert S. Mannel, Maurie Markman, Jacobus Pfisterer, Michael Quinn, Nick Reed, Ann Marie Swart, Jonathan S. Berek, Nicoletta Colombo, Gilles Freyer, Dolores Gallardo, Marie Plante, Andrés Poveda, Larry Rubinstein, Monica Bacon, Henry C Kitchener, Gavin Stuart
At the 4th Ovarian Cancer Consensus Conference of the Gynecologic Cancer
InterGroup (GCIG) held in Vancouver, Canada, in June 2010, representatives of 23
cooperative research groups studying gynecologic cancers gathered to establish
international consensus on issues critical to the conduct of large randomized
trials. The process focused on 13 predetermined questions. Group A, 1 of the 3
discussion... hiện toàn bộ
Role of Molecular Agents and Targeted Therapy in Clinical Trials for Women With Ovarian CancerInternational Journal of Gynecological Cancer - Tập 21 Số 4 - Trang 763-770 - 2011
Jonathan A. Ledermann, Christian Marth, Mark S. Carey, Michael J. Birrer, David D.L. Bowtell, Stan B. Kaye, Iain A. McNeish, Amit M. Oza, Giovanni Scambia, Gordon Rustin, Frederick B. Stehman, David M. Gershenson, Gillian Thomas, Els M.J.J. Berns, Antonio Casado, Nelleke Ottevanger, Felix Hilpert, Byoung‐Gie Kim, Aikou Okamoto, Monica Bacon, Henry C Kitchener, Gavin Stuart
There is now a greater understanding of the molecular pathways in ovarian
cancer, and using this knowledge, a large number of new therapeutic agents can
be tested. The success of these drugs will depend on selecting drugs that target
known key dysfunctional molecular pathways. To make best use of these compounds,
prognostic and predictive biomarkers need to be identified. Novel methods of
assessme... hiện toàn bộ