Inflammatory Bowel Diseases

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Ustekinumab for the Treatment of Refractory Crohnʼs Disease
Inflammatory Bowel Diseases - Tập 22 Số 7 - Trang 1662-1669 - 2016
Sam Khorrami, Daniel Ginard, Ignacio Marín‐Jiménez, María Chaparro, M Sierra, Mariam Aguas, Beatriz Sicilia, Valle García-Sánchez, Cristina Suárez-Mejías, Albert Villoría, Carlos Taxonera, Antonio Velasco-Guardado, Javier Martínez, Javier P. Gisbert
Ciprofloxacin or metronidazole for the treatment of perianal fistulas in patients with Crohnʼs disease: A randomized, double-blind, placebo-controlled pilot study
Inflammatory Bowel Diseases - Tập 15 Số 1 - Trang 17-24 - 2009
Kelvin T. Thia, Uma Mahadevan, Brian G. Feagan, Cindy Wong, Alan Cockeram, Alain Bitton, Çharles N. Bernstein, William J. Sandborn
Inflammatory Articular Disease in Patients with Inflammatory Bowel Disease
Inflammatory Bowel Diseases - Tập 21 Số 11 - Trang 2598-2604 - 2015
Saskia Ditisheim, Nicolas Fournier, Pascal Juillerat, Valérie Pittet, Pierre Michetti, Cem Gabay, Axel Finckh
Development of the Crohnʼs disease digestive damage score, the Lémann score
Inflammatory Bowel Diseases - Tập 17 Số 6 - Trang 1415-1422 - 2011
Benjamin Pariente, Jacques Cosnes, Silvio Danese, William J. Sandborn, M. Lewin, Joel G. Fletcher, Yehuda Chowers, Geert D’Haens, Brian G. Feagan, Toshifumi Hibi∥, Daniël W. Hommes, Jan E. Irvine, Michael A. Kamm, Edward V. Loftus, Édouard Louis, Pierre Michetti, Pia Munkholm, Tom Øresland, Julián Panés, Laurent Peyrin–Biroulet, Walter Reinisch, Bruce E. Sands, Juergen Schöelmerich, Stefan Schreiber, Herbert Tilg, Simon Travis, Gert Van Assche, Maurizio Vecchi, Jean Yves Mary, Jean‐Frédéric Colombel, Marc Lémann
Nonsteroidal Anti-inflammatory Drugs and Inflammatory Bowel Disease
Inflammatory Bowel Diseases - Tập 20 Số 12 - Trang 2493-2502 - 2014
Ibrahim Habib, Andrew Mazulis, Grigory Roginsky, Eli D. Ehrenpreis
Interleukin-23/Th17 pathways and inflammatory bowel disease
Inflammatory Bowel Diseases - Tập 15 Số 7 - Trang 1090-1100 - 2009
Clara Abraham, Judy H. Cho
Multidimensional Impact of Mediterranean Diet on IBD Patients
Inflammatory Bowel Diseases - Tập 27 Số 1 - Trang 1-9 - 2021
Fabio Chicco, Salvatore Magrì, Arianna Cingolani, Danilo Paduano, Mario Pesenti, Federica Zara, Francesca Tumbarello, Emanuela Urru, Alessandro Melis, Laura Casula, Massimo Claudio Fantini, Paolo Usai
Abstract Background & Aims Malnutrition with the accumulation of fat tissue and nonalcoholic fatty liver disease (NAFLD) are conditions associated with inflammatory bowel disease (IBD). Visceral fat and NAFLD-related liver dysfunction can both worsen intestinal inflammation. Because the Mediterranean diet (Md) has been shown to ameliorate both obesity and NAFLD, the aim of this study was to analyze the impact of Md on the nutritional state, liver steatosis, clinical disease activity, and quality of life (QoL) in IBD patients. Methods Patients with IBD, both Crohn’s disease (CD) and ulcerative colitis (UC), followed Md for 6 months. Their body mass index (BMI), body tissue composition, liver steatosis and function, serum lipid profile, clinical disease activity, and inflammatory biomarkers (C-reactive protein and fecal calprotectin) were collected at baseline (T0) and compared with those obtained after 6 months (T180) to evaluate the impact of Md. Results One hundred forty-two IBD patients, 84 UC and 58 CD, followed Md for 6 months. At T180, diet-adherent CD and UC improved BMI (UC −0.42, P = 0.002; CD −0.48, P = 0.032) and waist circumference (UC −1.25 cm, P = 0.037; CD −1.37 cm, P = 0.041). Additionally, the number of patients affected by liver steatosis of any grade was significantly reduced in both groups (UC T0 31 of 84 [36.9%] vs T180 18 of 84 [21.4%], P = 0.0016; CD T0 27 of 58 [46.6%] vs T180 18 of 58 [31.0%], P < 0.001) after dietary intervention. Finally, after 6 months of the diet, fewer UC and CD patients with stable therapy had active disease (UC T0 14 of 59 [23.7%] vs T180 4 of 59 [6.8%], P = 0.004; CD T0 9 of 51 [17.6%] vs T180 2 of 51 [3.0%], P = 0.011) and elevated inflammatory biomarkers. Mediterranean diet improved QoL in both UC and CD, but neither serum lipid profile nor liver function were modified by the diet. Conclusions A significant reduction of malnutrition-related parameters and liver steatosis was observed in both CD and UC patients after short-term dietary intervention based on the adoption of Md, and this was associated with a spontaneous improvement of disease activity and inflammatory markers.
Increased serum levels of L-arginine in ulcerative colitis and correlation with disease severity
Inflammatory Bowel Diseases - Tập 16 Số 1 - Trang 105-111 - 2010
Shih‐Kuang S. Hong, Brad E. Maltz, Lori A. Coburn, James C. Slaughter, Rupesh Chaturvedi, David A. Schwartz, Keith T. Wilson
L-Arginine Availability and Metabolism Is Altered in Ulcerative Colitis
Inflammatory Bowel Diseases - Tập 22 Số 8 - Trang 1847-1858 - 2016
Lori A. Coburn, Sara Horst, Margaret M. Allaman, Caroline T. Brown, Christopher S. Williams, Mallary E. Hodges, Jennifer P. Druce, Dawn B. Beaulieu, David A. Schwartz, Keith T. Wilson
Safety of immunomodulators and biologics for the treatment of inflammatory bowel disease during pregnancy and breast-feeding
Inflammatory Bowel Diseases - Tập 16 Số 5 - Trang 881-895 - 2010
Javier P. Gisbert
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