Toll-Like Receptor 2-Dependent Protection against Pneumococcal Carriage by Immunization with Lipidated Pneumococcal ProteinsInfection and Immunity - Tập 82 Số 5 - Trang 2079-2086 - 2014
Kristin Moffitt, Mojca Škoberne, A. Howard, L. Cristina Gavrilescu, Todd M. Gierahn, Scott Munzer, Bharat L. Dixit, Paul J. Giannasca, Jessica B. Flechtner, Richard Malley
ABSTRACTInfections withStreptococcus pneumoniaecause substantial morbidity and mortality, particularly in children in developing nations. Polysaccharide-conjugate vaccines provide protection against both invasive disease and colonization, but their use in developing countries is limited by restri...... hiện toàn bộ
Characterization of an amylase-binding component of Streptococcus gordonii G9BInfection and Immunity - Tập 60 Số 11 - Trang 4726-4733 - 1992
Frank A. Scannapieco, G G Haraszthy, M I Cho, Michael J. Levine
The goal of the present study was to begin characterizing the amylase-binding component(s) on the surface of Streptococcus gordonii G9B. Alkali extracts but not phenol-water extracts of this bacterium inhibited 125I-amylase binding to S. gordonii G9B. To identify the bacterial components involved in amylase binding, the alkali extract was subjected to affinity chromatography on amylase-Sep...... hiện toàn bộ
Isolation of a Chromosomal Region ofKlebsiella pneumoniaeAssociated with Allantoin Metabolism and Liver InfectionInfection and Immunity - Tập 72 Số 7 - Trang 3783-3792 - 2004
Huei‐Chi Chou, Cha‐Ze Lee, Li‐Chen Ma, Chi‐Tai Fang, Shan‐Chwen Chang, Jann‐Tay Wang
ABSTRACTKlebsiella pneumoniaeliver abscess with metastatic complications is an emerging infectious disease in Taiwan. To identify genes associated with liver infection, we used a DNA microarray to compare the transcriptional profiles of three strains causing liver abscess and three strains not associated with liver infection. There were 1...... hiện toàn bộ
Cationic Liposomes Containing Mycobacterial Lipids: a New Powerful Th1 Adjuvant SystemInfection and Immunity - Tập 73 Số 9 - Trang 5817-5826 - 2005
Ida Rosenkrands, Else Marie Agger, Anja Weinreich Olsen, Karen Smith Korsholm, Claire Swetman Andersen, Klaus T. Jensen, Peter Andersen
ABSTRACT
The immunostimulation provided by the mycobacterial cell wall has been exploited for many decades, e.g., in Freund's complete adjuvant. Recently, the underlying mechanism behind this adjuvant activity, including Toll receptor signaling, has begun to be unraveled, confirming the potential of mycobacterial constituents to act as adjuva...... hiện toàn bộ