Histopathology

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Ki67 protein: the immaculate deception?
Histopathology - Tập 40 Số 1 - Trang 2-11 - 2002
D C Brown, Kevin C. Gatter
Ki67 protein: the immaculate deception? This article updates our previous review of Ki67 published in Histopathology 10 years ago. In this period the numbers of papers published featuring this antibody has increased 10‐fold from 338 to 3489 indicating the considerable enthusiasm with which this antibody has been studied. T...... hiện toàn bộ
Synovitis score: discrimination between chronic low‐grade and high‐grade synovitis
Histopathology - Tập 49 Số 4 - Trang 358-364 - 2006
Veit Krenn, Lars Morawietz, Gerd R Burmester, Raimund W. Kinne, Ulf Mueller‐Ladner, B Müller, Frank Buttgereit
Aims : To standardize the histopathological assessment of synovial membrane specimens in order to contribute to the diagnostics of rheumatic and non‐rheumatic joint diseases.Methods and results : Three features of chronic synovitis (enlargement of lining cell layer, cellular density of synovial stroma, leukocytic infiltrate) we...... hiện toàn bộ
Maintenance of polarity and a dual cell population in adenoid cystic carcinoma of the breast: an immunohistochemical study
Histopathology - Tập 32 Số 3 - Trang 232-238 - 1998
Kasami, James R. Olson, Scot H. Simpson, Amanda J. Page
Aims:Adenoid cystic carcinoma (ACC) of the breast, although quite uncommon, is histologically distinct and has an excellent prognosis. Our purpose was to characterize molecular markers of cellular differentiation and polarity to define better the role that these combined features might play in the excellent prognosis of ACC in this site.... hiện toàn bộ
High sensitivity and specificity of immunohistochemistry for the detection of hormone receptors in breast carcinoma: comparison with biochemical determination in a prospective study of 793 cases
Histopathology - Tập 37 Số 6 - Trang 536-545 - 2000
B Zafrani, M.-H. Aubriot, E Mouret, Patricia de Crémoux, Yann De Rycke, Andrea Pujol Nicolas, E Boudou, Anne Vincent‐Salomon, H Magdelénat, Xavier Sastre‐Garau
The hormone receptor (HR) status of breast cancer is an important prognostic factor and predictive parameter of the response to hormone therapy. Enzyme immunoassay (EIA) is currently the standard for determination of HR, but immunohistochemistry (IHC) represents a potentially useful alternative. We used IHC to determine HR status in a large prospective study and compared the results to tho...... hiện toàn bộ
Adenoid cystic carcinoma of the breast: a case with axillary lymph node metastasis
Histopathology - Tập 10 Số 4 - Trang 415-424 - 1986
Christopher A. Wells, S Nicoll, David J. Conway
A breast tumour with proven lymph node metastasis is conclusively characterized as an adenoid cystic carcinoma using immunocytochemistry and electron microscopy. The majority of tumour cells showed certain of the characteristic features of myoepithetial cells while the pseudocystic spaces contained large amounts of reduplicated basal lamina. A small proportion of tumour cells, however, sho...... hiện toàn bộ
Calibration of immunohistochemistry for assessment of HER2 in breast cancer: results of the French Multicentre GEFPICS* Study
Histopathology - Tập 42 Số 4 - Trang 337-347 - 2003
Anne Vincent‐Salomon, Gaétan MacGrogan, Jérôme Couturier, Laurent Arnould, Yves Denoux, Maryse Fiche, J Jacquemier, M.C. Mathieu, Frédérique Penault-Llorca, C Rigaud, Pascal Roger, Isabelle Treilleux, M O Vilain, Simone Mathoulin‐Pélissier, V Le Doussal
Aims:  HER2 protein is over‐expressed in 15–30% of breast carcinomas. Immunohistochemistry (IHC) is a common and inexpensive method able to specifically detect HER2 protein. However, lack of standardization of IHC has been considered responsible for discrepancies in HER2 status assessment performed by IHC and fluorescence in‐situ hybridization (FISH). This prompted u...... hiện toàn bộ
Adenoid cystic carcinoma of the breast: a tumour commonly devoid of oestrogen receptors and related proteins
Histopathology - Tập 35 Số 3 - Trang 241-248 - 1999
Trendell‐Smith, Peston, Shousha
AimAdenoid cystic carcinoma (ACC) of the breast is an uncommon well‐differentiated tumour with good prognosis, and sometimes difficult to distinguish from in‐situ and invasive cribriform carcinoma (ICC) which are relatively more common. Recently, we encountered a case of ACC that proved to be totally oestrogen receptor (ER) negative by immunohistochemistr...... hiện toàn bộ
Slide navigation patterns among pathologists with long experience of digital review
Histopathology - Tập 67 Số 2 - Trang 185-192 - 2015
Jesper Molin, Morten Fjeld, Claudia Mello‐Thoms, Claes Lundström
AimsIn order to develop efficient digital pathology workstations, we studied the navigation patterns of pathologists diagnosing whole‐slide images. To gain a better understanding of these patterns, we built a conceptual model based on observations. We also determined whether or not new navigation patterns have emerged among pathologists with extensive dig...... hiện toàn bộ
Handling of radical prostatectomy specimens: total or partial embedding?
Histopathology - Tập 58 Số 2 - Trang 211-216 - 2011
Ben Vainer, Birgitte Grønkær Toft, Karen Ege Olsen, Grete Krag Jacobsen, Niels Marcussen
Vainer B, Toft B G, Olsen K E, Jacobsen G K & Marcussen N
(2011) Histopathology58, 211–216
Handling of radical prostatectomy specimens: total or partial embedding?Aims:  Proper examination and accurate reporting of radical prostatectomy specimens (RPS) is essential in determ...... hiện toàn bộ
Dysplastic naevi: an update
Histopathology - Tập 56 Số 1 - Trang 112-120 - 2010
David E. Elder
Elder D E
(2010) Histopathology56, 112–120
Dysplastic naevi: an updateDysplastic naevi are clinically atypical and histologically are characterized by architectural disorder and cytological atypia. Their diagnosis is reproducible if criteria and thresholds are agreed upon. They are significant only in...... hiện toàn bộ
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