Histopathology

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Ki67 protein: the immaculate deception?
Histopathology - Tập 40 Số 1 - Trang 2-11 - 2002
D C Brown, Kevin C. Gatter
Ki67 protein: the immaculate deception? This article updates our previous review of Ki67 published in Histopathology 10 years ago. In this period the numbers of papers published featuring this antibody has increased 10‐fold from 338 to 3489 indicating the considerable enthusiasm with which this antibody has been studied. T...... hiện toàn bộ
Adenoid cystic carcinoma of the breast: a case with axillary lymph node metastasis
Histopathology - Tập 10 Số 4 - Trang 415-424 - 1986
Christopher A. Wells, S Nicoll, David J. Conway
A breast tumour with proven lymph node metastasis is conclusively characterized as an adenoid cystic carcinoma using immunocytochemistry and electron microscopy. The majority of tumour cells showed certain of the characteristic features of myoepithetial cells while the pseudocystic spaces contained large amounts of reduplicated basal lamina. A small proportion of tumour cells, however, sho...... hiện toàn bộ
DOG1 and CD117 are the antibodies of choice in the diagnosis of gastrointestinal stromal tumours
Histopathology - Tập 57 Số 2 - Trang 259-270 - 2010
Marco Novelli, Sabrina Rossi, Manuel Rodriguez‐Justo, Philippe Tanière, Beatrice Seddon, Luisa Toffolatti, Chiara Sartor, Pancras C.W. Hogendoorn, Raf Sciot, M. van Glabbeke, Jaap Verweij, Jean‐Yves Blay, Peter Hohenberger, Adrienne M. Flanagan, Angelo Paolo Dei Tos
Novelli M, Rossi S, Rodriguez‐Justo M, Taniere P, Seddon B, Toffolatti L, Sartor C, Hogendoorn P C W, Sciot R, Van Glabbeke M, Verweij J, Blay J Y, Hohenberger P, Flanagan A & Dei Tos A P
(2010) Histopathology57, 259–270
DOG1 and CD117 are the antibodies of choice in the diagnosis of gastrointestinal stromal tumours... hiện toàn bộ
Metallothionein expression in human neoplasia
Histopathology - Tập 45 Số 2 - Trang 103-118 - 2004
Stamatis Theocharis, Alexandra Margeli, Jerzy Klijanienko, Gregory Kouraklis
The metallothionein family is a class of low‐molecular‐weight, cysteine‐rich proteins with high affinity for metal ions. Four major isoforms (metallothionein‐1, ‐2, ‐3, and ‐4) have been identified in mammals, involved in many pathophysiological processes, including metal ion homeostasis and detoxification, protection against oxidative damage, cell proliferation and apoptosis, drug and rad...... hiện toàn bộ
Reappraisal of the papillary urothelial neoplasm of low malignant potential (PUNLMP)
Histopathology - Tập 77 Số 4 - Trang 525-535 - 2020
Timothy D. Jones, Liang Cheng
Although the papillary urothelial neoplasm of low malignant potential (PUNLMP) diagnostic category was retained in the updated 2016 World Health Organisation (WHO) classification of tumours of the urinary system, there still exists a great deal of controversy regarding the biological behaviour of these tumours. We review PUNLMP tumours and histological grading with an emphasis on the histo...... hiện toàn bộ
Solitary fibrous tumour of the breast: distinction from myofibroblastoma
Histopathology - Tập 37 Số 2 - Trang 189-191 - 2000
Gaetano Magro, Angelo Sidoni, Michele Bisceglia
Urothelial carcinoma following augmentation cystoplasty: an aggressive variant with distinct clinicopathological characteristics and molecular genetic alterations
Histopathology - Tập 55 Số 2 - Trang 161-173 - 2009
Ming‐Tse Sung, Shaobo Zhang, Antonio López-Beltrán, Rodolfo Montironi, Ming‐Sheng Wang, Darrell D. Davidson, Michael O. Koch, Mark P. Cain, Richard C. Rink, Liang Cheng
Aims:  Patients who have undergone intestinal augmentation cystoplasty are at risk for developing latent vesicle malignancy. The aim was to evaluate the histological and immunohistochemical characteristics and molecular genetic alterations in these neoplasms.Methods and results:  Four patients developing urothelial neoplasms af...... hiện toàn bộ
Triple negative tumours: a critical review
Histopathology - Tập 52 Số 1 - Trang 108-118 - 2008
JS Reis‐Filho, Andrew Tutt
Breast cancer is a heterogeneous disease that encompasses several distinct entities with remarkably different biological characteristics and clinical behaviour. Currently, breast cancer patients are managed according to algorithms based on a constellation of clinical and histopathological parameters in conjunction with assessment of hormone receptor (oestrogen and progesterone receptor) st...... hiện toàn bộ
Gastrointestinal stromal tumours: an update
Histopathology - Tập 48 Số 1 - Trang 83-96 - 2006
Brian P. Rubin
Recently, there has been intense interest in the study of gastrointestinal stromal tumour (GIST); one might call it a virtual GIST revolution. This is due largely to the realization that most GISTs express KIT and harbour activating c‐KIT (KIT) or platelet‐derived growth factor receptor‐alpha (PDGFRA) receptor...... hiện toàn bộ
Micronodular thymoma with lymphoid stroma: an immunohistochemical study of the distribution of Langerhans cells and mature dendritic cells in six patients
Histopathology - Tập 66 Số 2 - Trang 300-307 - 2015
Yoshinori Ishikawa, Hisashi Tateyama, Megumi Yoshida, Koji Takami, Haruhisa Matsuguma, Tetsuo Taniguchi, Noriyasu Usami, Koji Kawaguchi, Takayuki Fukui, Futoshi Ishiguro, Shota Nakamura, Kohei Yokoi
AimsMicronodular thymoma with lymphoid stroma (MNT) is an uncommon variant of thymoma, characterized by multiple small nodules consisting of type A thymoma‐like cells, which are separated by abundant B lymphocytes. The aim of the study was to elucidate the pathogenesis of the stromal lymphoid h...... hiện toàn bộ
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