Epimorphin promotes human hepatocellular carcinoma invasion and metastasis through activation of focal adhesion kinase/extracellular signal-regulated kinase/matrix metalloproteinase-9 axisHepatology - Tập 54 Số 5 - Trang 1808-1818 - 2011
Yi Jia, Lei Shi, Junnian Zhou, Chunjiang Fu, Lin Chen, Hongfeng Yuan, Yunfang Wang, Xinlong Yan, Yingchen Xu, Quan Zeng, Wen Yue, Xuetao Pei
Renal failure after upper gastrointestinal bleeding in cirrhosis: Incidence, clinical course, predictive factors, and short-term prognosisHepatology - Tập 34 - Trang 671-676 - 2001
Andrés Cárdenas, Pere Ginès, Juan Uriz, Xavier Bessa, Joan Manuel Salmerón, Antoni Mas, Rolando Ortega, Blas Calahorra, Dara De Las Heras, Jaime Bosch, Vicente Arroyo, Juan Rodés
Systemic inflammation in decompensated cirrhosis: Characterization and role in acute‐on‐chronic liver failureHepatology - Tập 64 Số 4 - Trang 1249-1264 - 2016
J. J. Clariá, Rudolf Stauber, Minneke J. Coenraad, Richard Moreau, Rajeshwar P. Mookerjee, Marco Pavesi, Àlex Amorós, Esther Titos, José Alcaraz‐Quiles, Karl Oettl, Vı́ctor Vargas, Paolo Caraceni, Marco Domenicali, Carlo Alessandria, Alexander L. Gerbes, Julia Wendon, Frederik Nevens, Jonel Trebicka, Wim Laleman, Faouzi Saliba, Tania M. Welzel, Agustı́n Albillos, Thierry Gustot, Daniel Benten, François Durand, Pere Ginès, Mauro Bernardi, Vicente Arroyo
Acute‐on‐chronic liver failure (ACLF) in cirrhosis is characterized by acute decompensation (AD), organ failure(s), and high short‐term mortality. Recently, we have proposed (systemic inflammation [SI] hypothesis) that ACLF is the expression of an acute exacerbation of the SI already present in decompensated cirrhosis. This study was aimed at testing this hypothesis and included 522 patien...... hiện toàn bộ
Systemic inflammatory response and serum lipopolysaccharide levels predict multiple organ failure and death in alcoholic hepatitisHepatology - Tập 62 Số 3 - Trang 762-772 - 2015
Javier Michelena, José Altamirano, Juan G. Abraldeṣ, Silvia Affò, Oriol Morales‐Ibanez, Pau Sancho‐Bru, Marlene Domínguez, Juan Carlos García‐Pagán, Javier Fernández, Vicente Arroyo, Pere Ginès, Alexandre Louvet, Philippe Mathurin, Wajahat Z. Mehal, Juan Caballería, Ramón Bataller
Alcoholic hepatitis (AH) frequently progresses to multiple organ failure (MOF) and death. However, the driving factors are largely unknown. At admission, patients with AH often show criteria of systemic inflammatory response syndrome (SIRS) even in the absence of an infection. We hypothesize that the presence of SIRS may predispose to MOF and death. To test this hypothesis, we studied a co...... hiện toàn bộ