Head and Neck Pathology

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Myoepithelial Carcinoma Ex Pleomorphic Adenoma of the Maxillary Sinus: A Case Report and Review of Literature
Head and Neck Pathology - - 2021
Giovacchini Francesco, Caselli Emanuele, Monarchi Gabriele, Mitro Valeria, Sidoni Angelo, Tullio Antonio
Myoepithelial carcinoma ex pleomorphic adenoma is defined as a malignant epithelial neoplasm arising from a primary or recurrent benign pleomorphic adenoma. This type of tumor comprises 3.6% of all salivary gland tumors and 12% of malignant ones. Clinically, it most commonly presents as a firm mass in the parotid gland. The development of this neoplasm in the sinonasal and nasopharyngeal regions i...... hiện toàn bộ
Blastoid Mantle Cell Lymphoma of the Palate: Report of a Rare Aggressive Entity and Review of the Literature
Head and Neck Pathology - Tập 16 - Trang 631-642 - 2021
Maria Georgaki, Vasileios Ionas Theofilou, Efstathios Pettas, Evangelia Piperi, Eleana Stoufi, Panayiotis Panayiotidis, Nikolaos G. Nikitakis
Mantle cell lymphoma (MCL) is a well-defined, non-Hodgkin lymphoma of B-cell origin displaying diverse morphological phenotypes and variable disease course. The World Health Organization recognizes two aggressive histopathologic variants of this type of lymphoma: pleomorphic and blastoid MCL. To date, only few cases of MCL affecting the oral cavity have been reported. Additionally, the involvement...... hiện toàn bộ
Molecular Heterogeneity in Mucoepidermoid Carcinoma: Conceptual and Practical Implications
Head and Neck Pathology - Tập 7 - Trang 23-27 - 2013
Diana Bell, Adel K. El-Naggar
Mucoepidermoid carcinoma (MEC), the most common salivary gland malignancy of the upper aerodigestive tract and tracheobronchial tree, is also known for its considerable cellular heterogeneity including epidermoid, intermediate and mucin producing cells. Despite this structural and cellular heterogeneity, MEC is uniquely characterized by a specific translocation t(11; 19) (q12; p13), resulting in a...... hiện toàn bộ
Microcystic/Reticular Schwannoma Arising in the Submandibular Gland: A Rare Benign Entity that Mimics More Common Salivary Gland Carcinomas
Head and Neck Pathology - Tập 10 - Trang 374-378 - 2015
Ryan P. Lau, Jonathan Melamed, Melissa Yee-Chang, Sonya Marcus, Babak Givi, Ronaldo Zamuco
Microcystic/reticular schwannoma is a recently described variant of schwannoma with a predilection for the gastrointestinal tract, rarely involving the head/neck region. This is the first reported case involving the submandibular gland. We present a case in a 34 year old man with 4.5 cm submandibular mass. Fine needle aspiration suggested a spindle cell lesion. Frozen section evaluation raised the...... hiện toàn bộ
In Situ Melanoma of the Gingiva Associated with Dense Inflammation and Pigment Deposition: A Potential Diagnostic Pitfall in Evaluating Stromal Invasion
Head and Neck Pathology - Tập 10 - Trang 547-551 - 2016
Bruno Tavares Sedassari, Nelise Alexandre da Silva Lascane, André Luis Santana de Freitas, Mário Cláudio Mautoni, Mirian Nacagami Sotto, Marina Helena Cury Gallottini, Suzana Cantanhede Orsini Machado de Sousa, Décio dos Santos Pinto
Melanoma is a highly aggressive neoplasm in which the neoplastic cells display melanocytic differentiation. Less than 1 % of all melanomas arise in the mucosal surfaces of the oral cavity, with purely in situ lesions being exceedingly rare tumors, but with a favorable prognosis compared with invasive lesions. We describe the clinical, histopathological and immunohistochemical findings in an uncomm...... hiện toàn bộ
Sinonasal Eosinophilic Angiocentric Fibrosis: A Report of Four Cases and Review of Literature
Head and Neck Pathology - Tập 2 - Trang 309-315 - 2008
Reena Jain, Jennifer V. Robblee, Emerald O’Sullivan-Mejia, Jane Lea, Andrew Heller, William C. Faquin, Celeste N. Powers
Eosinophilic angiocentric fibrosis (EAF) is a rare, benign condition of unknown etiology involving the sinonasal tract and the upper respiratory airways, and rarely, larynx, and orbit. We report four cases of EAF identified, in three women and one man, aged 31, 57, 27, and 51 years, respectively. The patients complained of sinonasal obstructive symptoms of long duration, nasal masses, epiphora, an...... hiện toàn bộ
Clinicopathologic Characteristics of Young Patients with Oral Squamous Cell Carcinoma
Head and Neck Pathology -
Wadad Mneimneh, Bin Xu, Charles A Ghossein, Bayan Alzumaili, Shenon Sethi, Ian Ganly, Anjanie Khimraj, Snjezana Doğan, Nora Katabi
Hyalinizing Clear Cell Carcinoma: Report of Eight Cases and a Review of Literature
Head and Neck Pathology - Tập 3 - Trang 179-185 - 2009
E. D. O’Sullivan-Mejia, H. D. Massey, W. C. Faquin, C. N. Powers
Hyalinizing clear cell carcinoma (HCCC) is an extremely rare neoplasm with a female predominance, composed of nests of monomorphic clear cells within a hyaline stroma. This tumor often follows an indolent course and treatment includes wide surgical excision with or without adjuvant radiotherapy. We report eight cases of HCCC identified at two academic institutions in six women and two men, ranging...... hiện toàn bộ
NUT Midline Carcinoma of the Sublingual Gland: Clinical Presentation and Review
Head and Neck Pathology - Tập 11 Số 4 - Trang 460-468 - 2017
Nolan B. Seim, Ramez Philips, Lynn Schoenfield, Theodoros N. Teknos, James W. Rocco, Amit Agrawal, Enver Özer, Ricardo L. Carrau, Stephen Y. Kang, Matthew Old
Human Papillomavirus Testing in Head and Neck Squamous Cell Carcinoma in 2020: Where Are We Now and Where Are We Going?
Head and Neck Pathology - Tập 14 - Trang 321-329 - 2020
James S. Lewis
High risk human papillomavirus (HPV) has transformed head and neck oncology in the past several decades. Now that we have recognized that HPV-positive oropharyngeal squamous cell carcinoma (OPSCC) is a unique cancer type with distinct clinicopathologic features and favorable prognosis, it has become essential to test patients in routine practice. We have progressed greatly in our knowledge of this...... hiện toàn bộ
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