Haemophilia

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Multimodal blood loss prevention approach including intra‐articular tranexamic acid in primary total knee arthroplasty for patients with severe haemophilia A
Haemophilia - Tập 22 Số 4 - 2016
E. Carlos Rodríguez‐Merchán, J. A. Romero‐Garrido, Primitivo Gómez-Cardero
Sites of initial bleeding episodes, mode of delivery and age of diagnosis in babies with haemophilia diagnosed before the age of 2 years: a report from The Centers for Disease Control and Prevention’s (CDC) Universal Data Collection (UDC) project
Haemophilia - Tập 15 Số 6 - Trang 1281-1290 - 2009
Roshni Kulkarni, J. Michael Soucie, Jeanne M. Lusher, Rodney Presley, Amy D. Shapiro, M. John Gill, Marilyn J. Manco‐Johnson, Marion A. Koerper, Prasad Mathew, Thomas C. Abshire, Donna DiMichele, Keith Hoots, Robert L. Janco, Diane J. Nugent, S. Geraghty, Bruce L. Evatt
Summary.  Lack of detailed natural history and outcomes data for neonates and toddlers with haemophilia hampers the provision of optimal management of the disorder. We report an analysis of prospective data collected from 580 neonates and toddlers aged 0–2 years with haemophilia enrolled in the Universal Data Collection (UDC) surveillance project of the Centers for D...... hiện toàn bộ
More than menorrhagia: a review of the obstetric and gynaecological manifestations of bleeding disorders
Haemophilia - Tập 11 Số 4 - Trang 295-307 - 2005
Allison James
Summary. In women, menorrhagia may be the most common manifestation of a bleeding disorder, but it is not the only reproductive tract abnormality that women with bleeding disorders experience. Women with bleeding disorders appear to be at an increased risk of developing haemorrhagic ovarian cysts and possibly endometriosis. As they grow older, they may be more likely...... hiện toàn bộ
The obstetric and gynaecological management of women with inherited bleeding disorders – review with guidelines produced by a taskforce of UK Haemophilia Centre Doctors’ Organization
Haemophilia - Tập 12 Số 4 - Trang 301-336 - 2006
C. A. Lee, Claudia Chi, Sue Pavord, Paula Bolton‐Maggs, Debra Pollard, A. HINCHCLIFFE‐WOOD, Rezan A. Kadir
Summary.  The gynaecological and obstetric management of women with inherited coagulation disorders requires close collaboration between obstetrician/gynaecologists and haematologists. Ideally these women should be managed in a joint disciplinary clinic where expertise and facilities are available to provide comprehensive assessment of the bleeding disorder and a com...... hiện toàn bộ
Obstetric management in von Willebrand's disease: a report of 24 pregnancies and a reivesw of the literature
Haemophilia - Tập 1 Số 2 - Trang 140-144 - 1995
Bernard Ramsahoye, S. Davies, H. Dasani, J. F. Pearson
SummaryThe case records of 13 patients (24 pregnancies) with von Willebrand's disease (vWD) were studies rettospectively. The overall incidence of primary and secondary post‐partum haemorrhage (PPH) was 15.8% and 25% respectively, all primary PPH occurring in tyre 2 discase (3/14 deliveries, 21.4%). The risk of primary PPH in type 2 patients who did not receive pro...... hiện toàn bộ
von Willebrand disease (VWD): evidence‐based diagnosis and management guidelines, the National Heart, Lung, and Blood Institute (NHLBI) Expert Panel report (USA)1
Haemophilia - Tập 14 Số 2 - Trang 171-232 - 2008
William L. Nichols, MB Hultin, Allison James, M. J. Manco‐Johnson, Robert R. Montgomery, Thomas L. Ortel, Margaret E. Rick, J. Evan Sadler, Mark Weinstein, Barbara P. Yawn
Summary.  von Willebrand disease (VWD) is a commonly encountered inherited bleeding disorder affecting both males and females, causing mucous membrane and skin bleeding symptoms, and bleeding with surgical or other haemostatic challenges. VWD may be disproportionately symptomatic in women of child‐bearing age. It may also occur less frequently as an acquired disorder...... hiện toàn bộ
Management of von Willebrand disease: a guideline from the UK Haemophilia Centre Doctors' Organization
Haemophilia - Tập 10 Số 3 - Trang 218-231 - 2004
John Pasi, Paul W. Collins, David Keeling, Simon Brown, A. M. Cumming, Gerard Dolan, C. R. M. Hay, F. G. H. Hill, Michael Laffan, I. R. Peake
Summary.  von Willebrand disease (VWD) is the commonest inherited bleeding disorder. The aim of therapy for VWD is to correct the two defects of haemostasis in this disorder, impaired primary haemostasis because of defective platelet adhesion and aggregation and impaired coagulation as a result of low levels of factor VIII. The objective of this guideline is to infor...... hiện toàn bộ
The rare coagulation disorders – review with guidelines for management from the United Kingdom Haemophilia Centre Doctors' Organisation
Haemophilia - Tập 10 Số 5 - Trang 593-628 - 2004
Paula Bolton‐Maggs, David J. Perry, Elizabeth Chalmers, L. A. Parapia, J Wilde, Michael D. Williams, Peter W. Collins, Steve Kitchen, Gerard Dolan, Andrew Mumford
Summary.  The rare coagulation disorders are heritable abnormalities of haemostasis that may present significant difficulties in diagnosis and management. This review summarizes the current literature for disorders of fibrinogen, and deficiencies of prothrombin, factor V, FV + VIII, FVII, FX, the combined vitamin K‐dependent factors, FXI and FXIII. Based on both coll...... hiện toàn bộ
The prevalence of disorders of haemostasis in adolescents with menorrhagia referred to a haemophilia treatment centre
Haemophilia - Tập 13 Số 5 - Trang 627-632 - 2007
Sameh Mikhail, Ramya Varadarajan, Peter A. Kouides
Summary.  Menorrhagia at the time of menarche is relatively common and historically attributed primarily to immaturity of the pituitary–ovarian–uterine axis. Intuitively, a proportion of these patients should have an underlying disorder of haemostasis, given the 5–20% prevalence of von Willebrand’s disease and the ≥20% prevalence of platelet dysfunction in light of r...... hiện toàn bộ
Guideline on the selection and use of therapeutic products to treat haemophilia and other hereditary bleeding disorders
Haemophilia - Tập 14 Số 4 - Trang 671-684 - 2008
David Keeling, Robert C. Tait, Michael Makris
Summary.  Evidence‐based guidelines are presented on the selection and use of therapeutic products to treat haemophilia and other hereditary bleeding disorders. They include details of therapeutic products available in the UK and they update and replace previous United Kingdom Haemophilia Centre Doctors’ Organisation guidelines.
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