Gastric Cancer

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Irinotecan monotherapy as third-line or later treatment in advanced gastric cancer
Gastric Cancer - Tập 21 - Trang 464-472 - 2017
Akitaka Makiyama, Kohei Arimizu, Gen Hirano, Chinatsu Makiyama, Yuzo Matsushita, Tsuyoshi Shirakawa, Hirofumi Ohmura, Masato Komoda, Keita Uchino, Kyoko Inadomi, Shuji Arita, Hiroshi Ariyama, Hitoshi Kusaba, Yudai Shinohara, Miyuki Kuwayama, Tatsuhiro Kajitani, Hisanobu Oda, Taito Esaki, Koichi Akashi, Eishi Baba
Patients with advanced gastric cancer (AGC) are often treated with irinotecan monotherapy as salvage-line therapy. However, the survival benefit of this therapy remains to be elucidated. Medical records of AGC patients who were treated with irinotecan monotherapy as salvage-line treatment in six institutions from 2007 to 2014 were reviewed. A total of 146 patients had prior fluoropyrimidine and ta...... hiện toàn bộ
Long-term persistence of gastric dysbiosis after eradication of Helicobacter pylori in patients who underwent endoscopic submucosal dissection for early gastric cancer
Gastric Cancer - Tập 24 - Trang 710-720 - 2020
Toshio Watanabe, Yuji Nadatani, Wataru Suda, Akira Higashimori, Koji Otani, Shusei Fukunaga, Shuhei Hosomi, Fumio Tanaka, Yasuaki Nagami, Koichi Taira, Tetsuya Tanigawa, Geicho Nakatsu, Masahira Hattori, Yasuhiro Fujiwara
Gastric microbiome, other than Helicobacter pylori, plays a role in the tumorigenesis of gastric cancer (GC). Patients who undergo endoscopic submucosal dissection for early GC have a high risk of developing metachronous GC even after successful eradication of H. pylori. Thus, we investigated the microbial profiles and associated changes in such patients after the eradication of H. pylori. A total...... hiện toàn bộ
Brain metastases in gastroesophageal cancers—an underestimated complication
Gastric Cancer - Tập 25 - Trang 161-169 - 2021
Marius Brunner, Dominik Soll, Kathrin Adler, André Sasse, Ute König, Ardian Mekolli, Kristina Lowes, Johanna Reinecke, Volker Ellenrieder, Alexander König
Brain metastases represent a severe complication in many gastrointestinal malignancies especially those arising from the upper gastrointestinal tract, including cancer of the esophagus, gastroesophageal junction, and stomach (GEC). However, there is little knowledge about the onset or potential risk factors for brain metastases (BRMs) in upper gastrointestinal cancers resulting in a lack of screen...... hiện toàn bộ
Robotic gastrectomy for gastric cancer: systematic review and future directions
Gastric Cancer - Tập 26 Số 3 - Trang 325-338 - 2023
Susumu Shibasaki, Koichi Suda, Shigeo Hisamori, Kazutaka Obama, Masanori Terashima, Ichiro Uyama
Multidetector computed tomography for preoperative identification of left gastric vein location in patients with gastric cancer
Gastric Cancer - Tập 13 - Trang 25-29 - 2010
Kentaro Kawasaki, Shingo Kanaji, Iwao Kobayashi, Tadatoshi Fujita, Hiroaki Kominami, Kimihiko Ueno, Shinobu Tsutida, Masakazu Ohno, Masato Ohsawa, Yasuhiro Fujino, Masahiro Tominaga, Takeshi Nakamura
The area near the left gastric vein (LGV) is a challenging site at which to perform dissection of the lymph nodes during gastrectomy. Therefore, knowledge of the precise location of the LGV is important. The objective of this study was to examine the usefulness of multidetector computed tomography (MDCT) for the identification of the LGV. Eighty-one patients with gastric cancer underwent MDCT, whi...... hiện toàn bộ
Systematic review of pancreaticoduodenectomy for locally advanced gastric cancer
Gastric Cancer - Tập 15 - Trang 108-115 - 2011
Patrick Roberts, Rajini Seevaratnam, Roberta Cardoso, Calvin Law, Lucy Helyer, Natalie Coburn
The purpose of this study was to identify and synthesize findings from all articles on surgical and long-term outcomes in patients with gastric cancer undergoing gastrectomy combined with pancreaticoduodenectomy (PD). Electronic literature searches were conducted using Medline, EMBASE, and Cochrane databases from January 1, 1985, to December 31, 2009. Eight retrospective case series were included,...... hiện toàn bộ
Effects of initial disease status on lymph flow following gastrectomy in cases of carcinoma in the remnant stomach
Gastric Cancer - Tập 20 - Trang 457-464 - 2016
Shinsaku Honda, Etsuro Bando, Rie Makuuchi, Masanori Tokunaga, Yutaka Tanizawa, Taiichi Kawamura, Teiichi Sugiura, Yusuke Kinugasa, Katsuhiko Uesaka, Masanori Terashima
In cases of carcinoma in the remnant stomach (CRS), the lymphatic flow may be altered by the initial surgery. In this study of CRS after gastrectomy, we investigated how the regions of lymph node metastasis and changes in lymphatic flow depend on initial disease status. The study included 76 patients with CRS who underwent gastrectomy between September 2002 and November 2014. We analyzed and compa...... hiện toàn bộ
HER2 expression in locally advanced gastric cancer with extensive lymph node (bulky N2 or paraaortic) metastasis (JCOG1005-A trial)
Gastric Cancer - Tập 18 Số 3 - Trang 467-475 - 2015
Tomohiro Matsumoto, Mitsuru Sasako, Junki Mizusawa, Seiichi Hirota, Atsushi Ochiai, Ryoji Kushima, Hitoshi Katai, Yoïchi Tanaka, Noriyoshi Fukushima, Atsushi Nashimoto, Akira Tsuburaya
Combination therapy with S-1 and irinotecan (CPT-11) for advanced or recurrent gastric cancer
Gastric Cancer - Tập 12 - Trang 55-59 - 2009
Hiroya Takiuchi
S-1 and irinotecan (CPT-11) are active agents against gastric cancer. Some preclinical studies have demonstrated the theoretical background of combination therapy with S-1 and CPT-11 for gastric cancer. Based on these findings, several phase I/II studies of this combination therapy, which has been proposed as a candidate of standard treatment for advanced or recurrent gastric cancer in Japan, have...... hiện toàn bộ
A feasibility study of outpatient chemotherapy with S-1 + cisplatin in patients with advanced gastric cancer
Gastric Cancer - Tập 16 - Trang 41-47 - 2012
Shunsuke Okazaki, Takako E. Nakajima, Jun Hashimoto, Seiichiro Yamamoto, Daisuke Takahari, Ken Kato, Tetsuya Hamaguchi, Yasuhide Yamada, Yasuhiro Shimada, Kenji Tamura
Regimens of standard-dose cisplatin have usually been administered as inpatient chemotherapy in Japan. This prospective study evaluated the feasibility of outpatient chemotherapy with standard-dose cisplatin in Japanese patients with advanced gastric cancer. Advanced gastric cancer patients received an S-1 + cisplatin regimen (S-1: 80–120 mg days 1–21; cisplatin: 60 mg/m2 day 8, every 4–5 weeks), ...... hiện toàn bộ
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