FRONTIERS IN CHEMICAL ENGINEERING
SCOPUS (2019-2025)ESCI-ISI
2673-2718
Cơ quản chủ quản: Frontiers Media S.A.
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Nicotiana spp. for the Expression and Purification of Functional IgG3 Antibodies Directed Against the Staphylococcus aureus Alpha Toxin
Tập 3
Immunoglobulin subclass IgG1 is bound and neutralized effectively by
Staphylococcus aureus protein A, allowing the bacterium to evade the host’s
adaptive immune response. In contrast, the IgG3 subclass is not bound by protein
A and can be used to treat S. aureus infections, including drug-resistant
strains such as methicillin-resistant Staphylococcus aureus (MRSA). However, the
yields of recombina...