FEBS Journal

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Insect Immunity. Purification and Properties of Three Inducible Bactericidal Proteins from Hemolymph of Immunized Pupae of Hyalophora cecropia
FEBS Journal - Tập 106 Số 1 - Trang 7-16 - 1980
Dan Hultmark, Håkan Steiner, Torgny Rasmuson, Hans G. Boman
Three inducible bacteriolytic proteins, designated P7, P9A and P9B, from the hemolymph of immunized pupae of the giant silk moth Hyalophora cecropia have been purified using a two‐step procedure with cation‐exchange chromatography. Purified protein P7 has a molecular weight of 15000 and its amino acid composition shows a great similarity to that of the lysozyme from the wax moth Galleria mellonell... hiện toàn bộ
MicroRNA‐486‐5p, which is downregulated in hepatocellular carcinoma, suppresses tumor growth by targeting PIK3R1
FEBS Journal - Tập 282 Số 3 - Trang 579-594 - 2015
Xinping Huang, Jin Hou, Xiaoyun Shen, Chao‐Yuan Huang, Xuehui Zhang, Yu‐An Xie, Jiaxiang Ye
Deregulated microRNAs and their roles in carcinogenesis and cancer progression have attracted much attention. In previous studies conducted in our laboratory, the Illumina Solexa massively parallel signature sequencing of miRNomes in nontumor and hepatocellular carcinoma (HCC) tissues revealed that miR‐486‐5p was significantly downregulated in HCC, but its role in HCC development remains unknown. ... hiện toàn bộ
Conformational Transitions of Polynucleotides in Polymer Media
FEBS Journal - Tập 43 Số 2 - Trang 231-235 - 1974
Torvard C. Laurent, B. N. Preston, Birgit Carlsson
The melting temperature of three polynucleotides, poly(deoxyadenylic‐thymidylicf‐acid (double helix), calf‐thymus DNA and Staphylococcus aureus phage 80α DNA, increases in the presence of two neutral polymers, dextran and poly(ethyleneglycol). The results have been interpreted as a steric exclusion phenomenon. Two strands of polynucleotides in random coil conformation occupy a larger volume than a... hiện toàn bộ
The Covalently‐Bound Flavin of Hepatic Monoamine Oxidase
FEBS Journal - Tập 24 Số 2 - Trang 328-331 - 1971
Wolfram H. Walker, Edna B. Kearney, R. Seng, Thomas P. Singer
In the previous paper in this series it was shown that a pure flavin pentapeptide isolated from hepatic monoamine oxidase contains 1 mole each of serine and tyrosine and 2 moles of glycine, as well as an additional amino acid which is covalently linked to the 8α carbon of riboflavin. This amino acid has been identified as cysteine and the linkage to the flavin as a thioether on the basis of positi... hiện toàn bộ
The Covalently‐Bound Flavin of Hepatic Monoamine Oxidase
FEBS Journal - Tập 24 Số 2 - Trang 321-327 - 1971
Edna B. Kearney, James I. Salach, Wolfram H. Walker, R. Seng, William C. Kenney, Eileen Zeszotek, Thomas P. Singer
A method has been elaborated for the large scale isolation of outer membranes of beef liver mitochondria. From these monoamine oxidase was partially purified and digested with trypsin and chymotrypsin to yield peptides containing riboflavin covalently linked to the peptide chain. A pure pentapeptide of riboflavin‐5′‐phosphate has been obtained by a series of chromatographic procedures. Edman degra... hiện toàn bộ
Biochemical characterization of φX174‐protein‐E‐mediated lysis of Escherichia coli
FEBS Journal - Tập 180 Số 2 - Trang 393-398 - 1989
Angela Witte, Werner Lubitz
Energetic and permeability properties of Escherichia coli cells were determined prior to and during lysis caused by expression of the cloned gene E of bacteriophage φX174. Before onset of cell lysis the transmembrane gradients for K+, Na+ or Mg2+/ions, the level of ATP and the membrane potential, were unaffected. All these parameters changed simultaneously at the time of lysis onset, as monitored ... hiện toàn bộ
Phosphorylation of Focal Adhesion Vasodilator‐Stimulated Phosphoprotein at Ser157 in Intact Human Platelets Correlates with Fibrinogen Receptor Inhibition
FEBS Journal - Tập 225 Số 1 - Trang 21-27 - 1994
Karen Horstrup, Bernd Jablonka, Petra Hönig‐Liedl, Melitta Just, K. Kochsiek, Ulrich Walter
Integrins and other adhesion receptors are essential components for outside‐in and inside‐out signaling through the cell membrane. The platelet glycoprotein IIb‐IIIa (also known as fibrinogen receptor or integrin αIIbβ3) is activated by platelet agonists, inhibited by cyclic‐nucleotide‐elevating agents, and is involved in the activation of protein tyrosine kinases including the 125‐kDa focal adhes... hiện toàn bộ
Site‐specific phosphorylation of the purified receptor for calcium‐channel blockers by cAMP‐ and cGMP‐dependent protein kinases, protein kinase C, calmodulin‐dependent protein kinase II and casein kinase II
FEBS Journal - Tập 178 Số 2 - Trang 535-542 - 1988
Holger Jahn, Wolfgang Nastainczyk, Axel Röhrkasten, Toni Schneider, Franz Hofmann
Five protein kinases were used to study the phosphorylation pattern of the purified skeletal muscle receptor for calcium‐channel blockers (CaCB). cAMP kinase, cGMP kinase, protein kinase C, calmodulin kinase II and casein kinase II phosphorylated the 165‐kDa and the 55‐kDa proteins of the purified CaCB receptor. The 130/28‐kDa and the 32‐kDa protein of the receptor are not phosphorylated by these ... hiện toàn bộ
Energy-Coupling of the Transport System of Escherichia coli Dependent on Maltose-Binding Protein
FEBS Journal - Tập 75 Số 1 - Trang 187-193 - 1977
Thomas Ferenci, Winfried Boos, Maxime Schwartz, S Szmelcman
The Standard Redox Potential of Cysteine-Cystine from the Thiol-Disulphide Exchange Reaction with Glutathione and Lipoic Acid
FEBS Journal - Tập 2 Số 3 - Trang 327-331 - 1967
P. C. Jocelyn
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