European Journal of Neuroscience

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Dopamine D1‐like receptor antagonism in amygdala impairs the acquisition of glucose‐conditioned flavor preference in rats
European Journal of Neuroscience - Tập 30 Số 2 - Trang 289-298 - 2009
Khalid Touzani, Richard J. Bodnar, Anthony Sclafani
AbstractThis study examined the role of dopamine within the amygdala (AMY) in flavor preference learning induced by post‐oral glucose. In Experiment 1, rats were trained with a flavor [conditioned stimulus (CS+)] paired with intragastric (IG) infusions of 8% glucose and a different flavor (CS−) paired with IG water infusions. The CS+ preference was evaluated in two...... hiện toàn bộ
Synergistic stimulation of MHC class I and IRF‐1 gene expression by IFN‐γ and TNF‐α in oligodendrocytes
European Journal of Neuroscience - Tập 10 Số 9 - Trang 2975-2983 - 1998
Cristina Agresti, Antonietta Bernardo, Nicoletta Del Russo, Giovanna Marziali, Angela Battistini, Francesca Aloisi, Giovanni Levi, Eliana M. Coccia
AbstractIn order to understand the molecular basis of the synergistic action of interferon γ (IFN‐γ) and tumour necrosis factor α (TNF‐α) on rat oligodendrocyte development, we studied some aspects of the signalling pathways involved in the regulation of the major histocompatibility complex (MHC) class I and the interferon regulatory factor 1 (IRF‐1) gene expressio...... hiện toàn bộ
Characterization of neuronal migration disorders in neocortical structures: quantitative receptor autoradiography of ionotropic glutamate, GABAA and GABAB receptors
European Journal of Neuroscience - Tập 10 Số 10 - Trang 3095-3106 - 1998
Karl Zilles, M Qü, Axel Schleicher, Heiko J. Luhmann
AbstractEpileptiform activity was previously described [ hiện toàn bộ
Characterization of neuronal migration disorders in neocortical structures: extracellular in vitro recordings
European Journal of Neuroscience - Tập 10 Số 10 - Trang 3085-3094 - 1998
Heiko J. Luhmann, Kristin Raabe, M Qü, Karl Zilles
AbstractThe majority of patients showing neuronal migration disorders in cortical structures suffer from pharmaco‐resistant epilepsy. In order to study the molecular and cellular mechanisms underlying this pronounced hyperexcitability, we used an animal model of focal cortical dysplasia demonstrating structural malformations which resemble the human pathology of mi...... hiện toàn bộ
Adult Rat Dorsal Root Ganglion Neurons Extend Neurites on Predegenerated But Not on Normal Peripheral Nerves In Vitro
European Journal of Neuroscience - Tập 4 Số 3 - Trang 193-200 - 1992
Kuldip S. Bedi, Janet Winter, Martin Berry, James Cohen
AbstractThe abilities of embryonic and adult rat sensory neurons to regenerate were compared when cultured on cryostat sections of normal and lesioned sciatic nerve tissues. Differences in neurite growth, visualized by GAP‐43 immunolabelling, were most pronounced on substrata consisting of longitudinal sections of normal versus predegenerated sciatic nerve. Adult d...... hiện toàn bộ
Bypassing the Saccadic Pulse Generator: Possible Control of Head Movement Trajectory by Rat Superior Colliculus
European Journal of Neuroscience - Tập 3 Số 8 - Trang 790-801 - 1991
Sheila King, Paul Dean, Peter Redgrave
AbstractSaccades produced by electrical stimulation of the superior colliculus in primates are influenced primarily by the location of the stimulating electrode, with the suprathreshold intensity or frequency of the stimulating pulse train having little effect. Any given collicular site produces a characteristic movement of relatively fixed amplitude and velocity. ...... hiện toàn bộ
The role of anterior cingulate cortex and precuneus in the coordination of motor behaviour
European Journal of Neuroscience - Tập 22 Số 1 - Trang 235-246 - 2005
Nicole Wenderoth, Filiep Debaere, Stefan Sunaert, Stephan P. Swinnen
AbstractBehavioral studies in humans have shown that bimanual coordination imposes specific demands on the central nervous system that exceed unimanual task control. In the present study we used functional magnetic resonance imaging to investigate the neural correlate of this additional coordination effort, i.e. regions responding more strongly to bimanual movement...... hiện toàn bộ
Time‐sensitive enhancement of motor learning with the less‐affected forelimb after unilateral sensorimotor cortex lesions in rats
European Journal of Neuroscience - Tập 22 Số 8 - Trang 2069-2080 - 2005
J. Edward Hsu, Theresa A. Jones
AbstractUnilateral damage to the forelimb region of the sensorimotor cortex (FLsmc) results in time‐dependent changes in neuronal activity, structure and connectivity in the contralateral motor cortex of adult rats. These changes have been linked to facilitation of motor skill learning in the less‐affected/ipsilesional forelimb, which is likely to promote its use i...... hiện toàn bộ
Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease
European Journal of Neuroscience - Tập 15 Số 1 - Trang 120-132 - 2002
Julia Fuchs, Malin Andersson, Christian Winkler, Deniz Kirik, Nils Wierup, M. Angela Cenci
AbstractIn an attempt to define clinically relevant models of akinesia and dyskinesia in 6‐hydroxydopamine (6‐OHDA)‐lesioned rats, we have examined the effects of drugs with high (l‐DOPA) vs. low (bromocriptine) dyskinesiogenic potential in Parkinson's disease on three types of motor performance, namely: (i) abnormal involuntary movements (AIMs) ...... hiện toàn bộ
Motor discoordination and increased susceptibility to cerebellar injury in GLAST mutant mice
European Journal of Neuroscience - Tập 10 Số 3 - Trang 976-988 - 1998
Kei Watase, Kouichi Hashimoto, Masanobu Kano, Keiko Yamada, Masahiko Watanabe, Yoshiro Inoue, Shigeru Okuyama, Takashi Sakagawa, Shinichi Ogawa, Noritaka Kawashima, Seiji Hori, Masato Takimoto, Keiji Wada, Kohichi Tanaka
AbstractTo study the function of GLAST, a glutamate transporter highly expressed in the cerebellar Bergmann astrocytes, the mouse GLAST gene was inactivated. GLAST‐deficient mice developed normally and could manage simple coordinated tasks, such as staying on a stationary or a slowly rotating rod, but failed more challenging task such as staying on a quickly rotati...... hiện toàn bộ
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