European Journal of Neuroscience

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Pupil size tracks perceptual content and surprise
European Journal of Neuroscience - Tập 41 Số 8 - Trang 1068-1078 - 2015
Niels A. Kloosterman, Thomas Meindertsma, Anouk M. van Loon, Victor A. F. Lamme, Yoram Bonneh, Tobias H. Donner
AbstractChanges in pupil size at constant light levels reflect the activity of neuromodulatory brainstem centers that control global brain state. These endogenously driven pupil dynamics can be synchronized with cognitive acts. For example, the pupil dilates during the spontaneous switches of perception of a constant sensory input in bistable perceptual illusions. ...... hiện toàn bộ
Role of desensitization of AMPA receptors on the neuronal viability and on the [Ca2+]i changes in cultured rat hippocampal neurons
European Journal of Neuroscience - Tập 12 Số 6 - Trang 2021-2031 - 2000
António Francisco Ambrósio, Ana Paula Silva, João O. Malva, J. F. Mesquita, Arsélio P. Carvalho, Caetana M. Carvalho
AbstractWe investigated the role of desensitization of α‐amino‐3‐hydroxy‐5‐methyl‐isoxazole‐4‐propionate (AMPA) receptors on the neurotoxicity and on the [Ca2+]i changes induced by kainate or by AMPA in cultured rat hippocampal neurons. The neuronal viability was evaluated either by the 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diph...... hiện toàn bộ
Progressive abnormalities in skeletal muscle and neuromuscular junctions of transgenic mice expressing the Huntington's disease mutation
European Journal of Neuroscience - Tập 20 Số 11 - Trang 3092-3114 - 2004
Richard R. Ribchester, Derek Thomson, Nigel I. Wood, Timothy S. C. Hinks, Thomas H. Gillingwater, Thomas M. Wishart, Felipe A. Court, A. Jennifer Morton
AbstractHuntington's disease (HD) is a neurodegenerative disorder with complex symptoms dominated by progressive motor dysfunction. Skeletal muscle atrophy is common in HD patients. Because the HD mutation is expressed in skeletal muscle as well as brain, we wondered whether the muscle changes arise from primary pathology. We used R6/2 transgenic mice for our studi...... hiện toàn bộ
D1 and D2 Receptor Gene Expression in the Rat Frontal Cortex: Cellular Localization in Different Classes of Efferent Neurons
European Journal of Neuroscience - Tập 7 Số 5 - Trang 1050-1063 - 1995
Patrícia Gaspar, Bertrand Bloch, Catherine Le Moine
AbstractThe dopaminergic input to the frontal cortex has an important role in motor and cognitive functions. These effects are mediated by dopamine receptors both of type D1 and of type D2, although the neural circuits involved are not completely understood. We used in situ hybridization to determine the cellular localization of D1 and D2...... hiện toàn bộ
Relationship of arousal to circadian anticipatory behavior: ventromedial hypothalamus: one node in a hunger–arousal network
European Journal of Neuroscience - Tập 30 Số 9 - Trang 1730-1738 - 2009
Ana Cristina de Medeiros Ribeiro, Joseph LeSauter, Christophe Dupré, Donald W. Pfaff
AbstractThe mechanisms by which animals adapt to an ever‐changing environment have long fascinated scientists. Different forces, conveying information regarding various aspects of the internal and external environment, interact with each other to modulate behavioral arousal. These forces can act in concert or, at times, in opposite directions. These signals eventua...... hiện toàn bộ
Loss of Layer‐specific Astrocytic Glutamine Synthetase Immunoreactivity in Slice Cultures of Hippocampus
European Journal of Neuroscience - Tập 5 Số 2 - Trang 122-127 - 1993
Amin Derouiche, Bernd Heimrich, Michael Frotscher
AbstractGlutamine synthetase (GS) supposedly inactivates the excitatory neurotransmitter glutamate. By using immunocytochemistry for GS, we recently demonstrated a layer‐specific, perisynaptic distribution of GS‐immunoreactive astrocytes and their processes in perfusion‐fixed rat hippocampi. Highest levels of immunoreactivity were found in well defined termination ...... hiện toàn bộ
Fluorescent Dye Prelabelled Microglial Cells Migrate into Organotypic Hippocampal Slice Cultures and Ramify
European Journal of Neuroscience - Tập 9 Số 4 - Trang 863-866 - 1997
Nils P. Hailer, Frank L. Heppner, Dorit Haas, Robert Nitsch
AbstractMicroglial cells with their characteristic ramified morphology are exclusively found in healthy CNS tissue, whereas various pathologies are associated with the occurrence of amoeboid, macrophage‐like cells. It is still a matter of discussion whether amoeboid cells are blood‐derived macrophages, or whether a characteristic change in morphology, reflecting ac...... hiện toàn bộ
Coronin 3 and its role in murine brain morphogenesis
European Journal of Neuroscience - Tập 21 Số 5 - Trang 1155-1168 - 2005
Andreas Hasse, André Rosentreter, Ziqiang Spoerl, Maria Stumpf, Angelika A. Noegel, Christoph S. Clemen
AbstractCoronins belong to the fundamental WD40‐repeat proteins. They are mainly found at the submembraneous area, they bind F‐actin in vitro, and most of the seven mammalian coronins have unclear roles. Coronin 3 is abundantly expressed in the adult CNS. All murine brain areas express coronin 3 during embryogenesis and the first postnata...... hiện toàn bộ
Neuronal and Glial Glutamate Transporters Possess an SH‐based Redox Regulatory Mechanism
European Journal of Neuroscience - Tập 9 Số 6 - Trang 1236-1243 - 1997
Davide Trotti, Barbara Lodi Rizzini, Daniela Rossi, Øyvind Haugeto, Giorgio Racagni, Niels C. Danbolt, Andrea Volterra
AbstractGlutamate uptake into nerve cells and astrocytes via high‐affinity transporters controls the extracellular glutamate concentration in the brain, with major implications for physiological excitatory neurotransmission and the prevention of excitotoxicity. We report here that three recently cloned rat glutamate transporter subtypes, viz.... hiện toàn bộ
Quy định về sự biểu hiện của miRNA trong quá trình đặc hiệu của tế bào thần kinh Dịch bởi AI
European Journal of Neuroscience - Tập 21 Số 6 - Trang 1469-1477 - 2005
Lena Smirnova, Anja Gräfe, A. Seiler, Stefan Schumacher, Robert Nitsch, F. Gregory Wulczyn
Tóm tắtMicroRNA (miRNA) là một loại phân tử RNA nhỏ không mã hóa mới được công nhận, tham gia vào việc kiểm soát phát triển của biểu hiện gen. Chúng tôi đã nghiên cứu sự điều tiết của một bộ miRNA thần kinh có biểu hiện cao trong quá trình phát triển não ở chuột. Kiểm soát tạm thời là một đặc điểm của điều tiết miRNA ở C. elegans... hiện toàn bộ
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