European Journal of Neuroscience

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Characterization of neuronal migration disorders in neocortical structures: quantitative receptor autoradiography of ionotropic glutamate, GABAA and GABAB receptors
European Journal of Neuroscience - Tập 10 Số 10 - Trang 3095-3106 - 1998
Karl Zilles, M Qü, Axel Schleicher, Heiko J. Luhmann
AbstractEpileptiform activity was previously described [ hiện toàn bộ
Characterization of neuronal migration disorders in neocortical structures: extracellular in vitro recordings
European Journal of Neuroscience - Tập 10 Số 10 - Trang 3085-3094 - 1998
Heiko J. Luhmann, Kristin Raabe, M Qü, Karl Zilles
AbstractThe majority of patients showing neuronal migration disorders in cortical structures suffer from pharmaco‐resistant epilepsy. In order to study the molecular and cellular mechanisms underlying this pronounced hyperexcitability, we used an animal model of focal cortical dysplasia demonstrating structural malformations which resemble the human pathology of mi...... hiện toàn bộ
Visual presentation of novel objects and new spatial arrangements of objects differentially activates the medial temporal lobe subareas in humans
European Journal of Neuroscience - Tập 19 Số 7 - Trang 1939-1949 - 2004
Maija Pihlajamäki, Heikki Tanila, Mervi Könönen, Tuomo Hänninen, Anne Hämäläinen, Hilkka Soininen, Hannu J. Aronen
AbstractA number of studies in rodents and monkeys report a distinction between the contributions of the hippocampus and perirhinal cortex to memory, such that the hippocampus is crucial for spatial memory whereas the perirhinal cortex has a pivotal role in perception and memory for visual objects. To determine if there is such a distinction in humans, we conducted...... hiện toàn bộ
Massive somatic deafferentation and motor deefferentation of the lower part of the body impair its visual recognition: a psychophysical study of patients with spinal cord injury
European Journal of Neuroscience - Tập 36 Số 11 - Trang 3509-3518 - 2012
Simone Pernigo, Valentina Moro, Renato Avesani, C Sosa Miatello, Cosimo Urgesi, Salvatore Maria Aglioti
AbstractEmbodied cognition theories postulate that perceiving and understanding the body states of other individuals are underpinned by the neural structures activated during first‐hand experience of the same states. This suggests that one’s own sensorimotor system may be used to identify the actions and sensations of others. Virtual and real brain lesion studies s...... hiện toàn bộ
Myelin and oligodendrocyte lineage cell dysfunctions: New players in the etiology and treatment of depression and stress‐related disorders
European Journal of Neuroscience - Tập 53 Số 1 - Trang 281-297 - 2021
Enrica Boda
AbstractDepressive disorders are complex, multifactorial disorders that have been traditionally attributed exclusively to neuronal abnormalities. However, recent studies have increased our understanding of the contribution of glial cells—and particularly of oligodendroglia—to the pathogenesis and treatment outcome of depression and stress‐related disorders. This re...... hiện toàn bộ
Pyruvate and lactate protect striatal neurons against N‐methyl‐d‐aspartate‐induced neurotoxicity
European Journal of Neuroscience - Tập 11 Số 9 - Trang 3215-3224 - 1999
M. Maus, Philippe Marin, Maurice Israël, J. Głowiński, Joël Prémont
AbstractA sustained release of glutamate contributes to neuronal loss during cerebral ischaemia. Using cultured mouse striatal neurons, we observed that glucose deprivation, which occurs in this pathological process, enhanced the N‐Methyl‐d‐aspartate (NMDA)‐ or α‐amino‐3‐hydroxy‐5‐methylisoxazole‐4‐propionate (AMPA)‐induced neurotoxicity. The end...... hiện toàn bộ
Variations in the human cannabinoid receptor (CNR1) gene modulate striatal responses to happy faces
European Journal of Neuroscience - Tập 23 Số 7 - Trang 1944-1948 - 2006
Bhismadev Chakrabarti, Lindsey Kent, John Suckling, Edward T. Bullmore, Simon Baron‐Cohen
AbstractHappy facial expressions are innate social rewards and evoke a response in the striatum, a region known for its role in reward processing in rats, primates and humans. The cannabinoid receptor 1 (CNR1) is the best‐characterized molecule of the endocannabinoid system, involved in processing rewards. We hypothesized that genetic variation in human ... hiện toàn bộ
Protein SUMOylation modulates calcium influx and glutamate release from presynaptic terminals
European Journal of Neuroscience - Tập 29 Số 7 - Trang 1348-1356 - 2009
Marco Feligioni, Atsushi Nishimune, Jeremy M. Henley
AbstractPosttranslational modification by small ubiquitin‐like modifier (SUMO) proteins is emerging as an important regulatory mechanism for neuronal function and dysfunction. Although multiple potential presynaptic SUMOylation substrate proteins have been proposed from sequence analysis the functional consequences of presynaptic SUMOylation have not been determine...... hiện toàn bộ
Immunohistochemical Localization of Five Members of the KV1 Channel Subunits: Contrasting Subcellular Locations and Neuron‐specific Co‐localizations in Rat Brain
European Journal of Neuroscience - Tập 7 Số 11 - Trang 2189-2205 - 1995
Rüdiger W. Veh, Ralf Lichtinghagen, Sabine Sewing, Frank Wunder, Isabella M. Grumbach, Olaf Pongs
AbstractA large variety of potassium channels is involved in regulating integration and transmission of electrical signals in the nervous system. Different types of neurons, therefore, require specific patterns of potassium channel subunit expression and specific regulation of subunit coassembly into heteromultimeric channels, as well as subunit‐specific sorting an...... hiện toàn bộ
Preserved Recognition Memory for Small Sets, and Impaired Stimulus Identification for Large Sets, Following Rhinal Cortex Ablations in Monkeys
European Journal of Neuroscience - Tập 6 Số 9 - Trang 1466-1478 - 1994
Madeline J. Eacott, David Gaffan, Elisabeth A. Murray
AbstractSeven cynomolgus monkeys (Macaca fascicularis) performed a series of tasks designed to assess their visual memory and their ability to identify visual stimuli. Preoperatively they were trained and tested in delayed and simultaneous matching‐to‐sample, both with a large stimulus set and with a small stimulus set; there were ∼500 mi...... hiện toàn bộ
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