A slowly developing dysfunction of dopaminergic nigrostriatal neurons induced by long‐term paraquat administration in rats: an animal model of preclinical stages of Parkinson's disease?European Journal of Neuroscience - Tập 22 Số 6 - Trang 1294-1304 - 2005
K Ossowska, Jadwiga Wardas, Maria Śmiałowska, Katarzyna Kuter, Tomasz Lenda, Joanna M. Wierońska, Barbara Zięba, Przemysław Nowak, Jolanta Dąbrowska, Aleksandra Bortel, Adam Kwieciński, S Wolfarth
AbstractThe aim of the present study was to examine the influence of the long‐term paraquat administration on the dopaminergic nigrostriatal system in rats. Paraquat was injected at a dose of 10 mg/kg i.p. for 4–24 weeks. We found that this pesticide reduced the number of tyrosine hydroxylase‐immunoreactive neurons of the substantia nigra; after the 4‐week treatmen...... hiện toàn bộ
Postnatal loss of Merkel cells, but not of slowly adapting mechanoreceptors in mice lacking the neurotrophin receptor p75European Journal of Neuroscience - Tập 11 Số 11 - Trang 3963-3969 - 1999
Ilka Kinkelin, Cheryl L. Stucky, Martin Koltzenburg
AbstractMerkel cells are specialized epidermal cells which are abundantly found in touch‐sensitive areas and which are innervated by slowly adapting mechanosensitive afferent fibres with large myelinated (Aβ) axons. The role of Merkel cells in mechanosensation, their developmental regulation and their influence on sensory neuron function are, however, incompletely ...... hiện toàn bộ
Dopamine D1‐like receptor antagonism in amygdala impairs the acquisition of glucose‐conditioned flavor preference in ratsEuropean Journal of Neuroscience - Tập 30 Số 2 - Trang 289-298 - 2009
Khalid Touzani, Richard J. Bodnar, Anthony Sclafani
AbstractThis study examined the role of dopamine within the amygdala (AMY) in flavor preference learning induced by post‐oral glucose. In Experiment 1, rats were trained with a flavor [conditioned stimulus (CS+)] paired with intragastric (IG) infusions of 8% glucose and a different flavor (CS−) paired with IG water infusions. The CS+ preference was evaluated in two...... hiện toàn bộ
Effects of aspiration versus neurotoxic lesions of the amygdala on emotional responses in monkeysEuropean Journal of Neuroscience - Tập 11 Số 12 - Trang 4403-4418 - 1999
Martine Meunier, Jocelyne Bachevalier, Elisabeth A. Murray, Ludiše Málková, Mortimer Mishkin
AbstractAll previous reports describing alterations in emotional reactivity after amygdala damage in monkeys were based on aspiration or radiofrequency lesions which likely disrupted fibres of passage coursing to and from adjacent ventral and medial temporal cortical areas. To determine whether this associated indirect damage was responsible for some or all of the ...... hiện toàn bộ
Longitudinal magnetic resonance imaging study of rhesus monkey brain developmentEuropean Journal of Neuroscience - Tập 24 Số 11 - Trang 3204-3212 - 2006
Ludiše Málková, Eric Heuer, Richard C. Saunders
AbstractTo examine early brain development, T1‐weighted structural MRI scans of seven rhesus monkeys (Macaca mulatta) were obtained longitudinally between the ages of 1 week and 4 years at 12 age points. Total brain volume, calculated at each age point, increased significantly, by 56%, between 1 week and 4 years. The greatest increase of ...... hiện toàn bộ
Sprouting and Regeneration of Lesioned Corticospinal Tract Fibres in the Adult Rat Spinal CordEuropean Journal of Neuroscience - Tập 5 Số 9 - Trang 1156-1171 - 1993
Lisa Schnell, Martin E. Schwab
AbstractWe have studied the effects of tissue transplants and antibodies (IN‐1) against the myelin‐associated neurite growth inhibitory proteins on sprouting and regeneration of the rat corticospinal tract (CST). Transplantation of embryonic spinal cord tissue into bilateral transection lesions of the lower thoracic spinal cord in young adult rats resulted in a mar...... hiện toàn bộ
Single Channel Recording from Glial Cells on the Untreated Surface of the Frog Optic NerveEuropean Journal of Neuroscience - Tập 3 Số 8 - Trang 813-819 - 1991
Héctor Marrero, Paula M. Orkand, Helmut Kettenmann, R. K. Orkand
AbstractThe patch clamp technique has been used to record single channel currents from the untreated surface of the intact frog optic nerve after the meninges and basal lamina have been mechanically removed. Cells filled via dialysis with Lucifer yellow (LY) from the patch pipette had a typical astrocyte morphology and were dye‐coupled to adjacent astrocytes. This ...... hiện toàn bộ