AnnouncementsEuropean Journal of Clinical Pharmacology - Tập 28 - Trang 108-108 - 1985
A clinically relevant pharmacokinetic interaction between cyclosporine and imatinibEuropean Journal of Clinical Pharmacology - - 2016
Ferdows Atiq, Annoek E C Broers, Louise M Andrews, Jeanette K Doorduijn, Birgit C P Koch, Teun Van Gelder, Jorie Versmissen
Cyclosporine A (CsA) and imatinib are both CYP3A4 and P-glycoprotein substrates. Concomitant use after hematopoietic stem cell transplantation (HSCT) for chronic myeloid leukemia (CML) or Philadelphia chromosome-positive (Ph+) acute lymphatic leukemia (ALL) may therefore result in a pharmacokinetic interaction. Although case reports and a recent small study in children indeed suggested there is a ...... hiện toàn bộ
Relationship between hemoglobin levels and vancomycin clearance in patients with sepsisEuropean Journal of Clinical Pharmacology - Tập 75 Số 7 - Trang 929-937 - 2019
Masayuki Chuma, Makoto Makishima, Toru Imai, Naohiro Tochikura, Shinichiro Suzuki, Tsukasa Kuwana, Nami Sawada, So Iwabuchi, Masao Sekimoto, Takahiro Nakayama, Takako Sakaue, Norikazu Kikuchi, Yoshikazu Yoshida, Kosaku Kinoshita
AnnouncementsEuropean Journal of Clinical Pharmacology - Tập 38 - Trang 212-212 - 1990
Haemodynamic studies on the antihypertensive effect of guancydineEuropean Journal of Clinical Pharmacology - Tập 3 - Trang 63-67 - 1971
J. Stenberg, R. Sannerstedt, L. Werkö
Guancydine, a new antihypertensive agent, was given orally in divided doses up to 1000 mg a day, to five male in-patients with severe arterial hypertension. Haemodynamic parameters were determined at rest and during standardized exercise before and after seven to fourteen days of treatment. In the second study significant reductions in the systemic vascular resistance were found which paralleled t...... hiện toàn bộ
Lack of effect of cimetidine on the pharmacokinetics and metabolism of a single oral dose of metronidazoleEuropean Journal of Clinical Pharmacology - Tập 35 - Trang 65-68 - 1988
S. Loft, M. Døssing, J. Sonne, K. Dalhof, K. Bjerrum, H. E. Poulsen
The time course of the effect of cimetidine on the pharmacokinetics of metronidazole was investigated in 6 healthy volunteers. Cimetidine 1.0 g/day was administered for 9-days and metronidazole 500 mg was administered orally on the second and eighth days, and in a control experiment. During cimetidine treatment the plasma kinetics of metronidazole and its partial clearance by renal excretion of th...... hiện toàn bộ