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No Generation, Blood Pressure and Vascular Stiffness: Lessons from the Angiotensin AT2 Receptor
Elsevier BV - - 2014
T. Unger
Vascular remodeling participates in the development and progression of cardiovascular conditions such as hypertension, atherosclerosis or aneurysm. This process is fine-tuned by neuro-humoral regulatory pathways: the renin-angiotensin system (RAS), being one of the most important. Chronic RAS activation, via AT1 receptor (AT1R) stimulation sets on a series of pro-proliferative, pro-fibrotic, pro-i...... hiện toàn bộ
P9.14 Increased Carotid Artery Stiffness Decreases Measured Carotid-Femoral Pulse Wave Velocity and Effects the Estimation of Age Dependency of Aortic Stiffness
Elsevier BV - - 2014
M. Butlin, A. Avolio
Carotid-femoral pulse wave velocity (PWVcf) is promoted as a clinical marker of aortic stiffness and is a measure utilising two sites where the pulse can be obtained non-invasively. PWVcf calculation requires subtraction of the heart-to-carotid pulse transit time from the heart-to-femoral pulse transit time. This implies that an independent increase in carotid stiffness (PWVc) will decrease PWVcf....... hiện toàn bộ
P10.11 THE EFFECT OF WALL MOTION ON THE HAEMODYNAMICS OF MIDDLE CEREBRAL ARTERY (MCA) ANEURYSM
Elsevier BV -
Tahere Sadat Safavi, Malikeh Nabaei, Nasser Fatouraee
P6.12 Brachial Artery Reactivity is Directly Proportional to Basal Brachial Artery Tone: Possible Confounder in Measuring Endothelial Function
Elsevier BV - - 2009
V. Maher, C. Markham, A. OHalloran, M. O’Dowd, M. Carey, A. Brown, D. McInerney
Brachial artery reactivity following compression is used as a surrogate marker of endothelial function. Brachial diameter increases exceeding 10% indicate normal endothelial function. We investigated if basal brachial artery tone influenced brachial artery reactivity. One hundred never smoking, healthy, normotensive, normolipidaemic subjects (41 + 9 yrs, 71F, 29 M) underwent brachial artery assess...... hiện toàn bộ
5.2 Differential Characteristics Between Aortic Pressure Augmentation and Carotid Flow Augmentation: Clinical Implications for Cerebral White Matter Hyperintensities
Elsevier BV - - 2018
Junichiro Hashimoto, Berend Westerhof, Sadayoshi Ito
Aortic stiffness and pressure wave reflection have been found to be associated with age-related cerebral microvascular disease, but the underlying mechanism remains obscure. We hypothesized that cerebral (carotid) flow augmentation potentially mediates these associations. Doppler waveforms were recorded in 286 patients with hypertension to measure the carotid flow augmentation index (FAIx) as the ...... hiện toàn bộ
A numerical study on the application of the functionally graded bioabsorbable materials in the stent design
Elsevier BV -
Hossein Bahreinizad, Milad Salimi Bani, Arezoo Khosravi, Alireza Karimi
P1.01 Treatment with Dexamethasone Reverses Impared Elastogenesis and Collagenogenesis in Cultures of Fibroblasts from Patients with Loeys-Dietz Syndrome (LDS)
Elsevier BV - - 2008
T. J. Bradley, C. P. Barnett, D. Chitayat, A. Hinek
LDS is an autosomal dominant condition caused by mutations in the TGFBR1 and TGFBR2 genes. The condition is associated with vascular tortuousity and formation and rupture of arterial aneurysms. Recent successful use of losartan in the Marfan mouse model has raised hope for medical treatment of LDS. Here we report a promising in vitro response in dexamethasone-treated cultured fibroblasts from thre...... hiện toàn bộ
Functional Genomics and Arterial Stiffness
Elsevier BV - - 2007
Celine Fassot-Lucht
Arterial stiffness, which has an independent predictive value for cardiovascular events, is influenced by genetic factors. The molecules underlying the process of arterial stiffening and, specifically, the identification of molecules that can contribute quantitatively to arterial stiffness are still largely unknown. The present report proposes an integrated view of the molecular determinants of ar...... hiện toàn bộ
P.036 ADMA — a Sensitive Marker of Endothelial Dysfunction in Children with Familiar Hypercholesterolemia and Diabetes Mellitus Type 1
Elsevier BV - - 2019
P. Jehlicka, F. Stozicky, O. Mayer
children with familiar hypercholesterolemia (FH) and diabetes mellitus type 1 (DM1) are considered to be high risk groups for the early manifestation of atherosclerosis. Endothelial dysfunction (ED) should be assessed in the preclinical stage, before clinical symptoms of vascular complications occur. Besides ultrasonographic methods there are many biochemical markers of ED whose varying sensitivit...... hiện toàn bộ
P142 Early Vascular Parameters in the Micro- and Macrocirculation in Type 2 Diabetes
Elsevier BV - - 2018
Christian Ott, Dennis Kannenkeril, Marina Karg, Agnes Bosch, Joanna Harazny, Roland Schmieder
Diabetes converts from a metabolic disorder into a predominantly vascular disease, once its duration extends over several years or/ and when additional cardiovascular risk factors such as hypertension coexist. We analyzed various vascular parameters in the renal, retinal and systemic circulation, with the goal to identify which vascular parameter of early organ damage is the earliest that can be c...... hiện toàn bộ
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