No Generation, Blood Pressure and Vascular Stiffness: Lessons from the Angiotensin AT2 ReceptorElsevier BV - - 2014
T. Unger
Vascular remodeling participates in the development and progression of cardiovascular conditions such as hypertension, atherosclerosis or aneurysm. This process is fine-tuned by neuro-humoral regulatory pathways: the renin-angiotensin system (RAS), being one of the most important. Chronic RAS activation, via AT1 receptor (AT1R) stimulation sets on a series of pro-proliferative, pro-fibrotic, pro-i...... hiện toàn bộ
P6.12 Brachial Artery Reactivity is Directly Proportional to Basal Brachial Artery Tone: Possible Confounder in Measuring Endothelial FunctionElsevier BV - - 2009
V. Maher, C. Markham, A. OHalloran, M. O’Dowd, M. Carey, A. Brown, D. McInerney
Brachial artery reactivity following compression is used as a surrogate marker of endothelial function. Brachial diameter increases exceeding 10% indicate normal endothelial function. We investigated if basal brachial artery tone influenced brachial artery reactivity. One hundred never smoking, healthy, normotensive, normolipidaemic subjects (41 + 9 yrs, 71F, 29 M) underwent brachial artery assess...... hiện toàn bộ
Functional Genomics and Arterial StiffnessElsevier BV - - 2007
Celine Fassot-Lucht
Arterial stiffness, which has an independent predictive value for cardiovascular events, is influenced by genetic factors. The molecules underlying the process of arterial stiffening and, specifically, the identification of molecules that can contribute quantitatively to arterial stiffness are still largely unknown. The present report proposes an integrated view of the molecular determinants of ar...... hiện toàn bộ
P142 Early Vascular Parameters in the Micro- and Macrocirculation in Type 2 DiabetesElsevier BV - - 2018
Christian Ott, Dennis Kannenkeril, Marina Karg, Agnes Bosch, Joanna Harazny, Roland Schmieder
Diabetes converts from a metabolic disorder into a predominantly vascular disease, once its duration extends over several years or/ and when additional cardiovascular risk factors such as hypertension coexist. We analyzed various vascular parameters in the renal, retinal and systemic circulation, with the goal to identify which vascular parameter of early organ damage is the earliest that can be c...... hiện toàn bộ