Elsevier BV
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Sustained viral activity of epstein-Barr virus contributes to cellular immortalization of lymphoblastoid cell lines
Elsevier BV - Tập 27 - Trang 143-148 - 2009
EBV-transformed lymphoblastoid cell lines (LCLs) are used as a resource for
human genetic, immunological, and pharmacogenomic studies. We investigated the
biological activity of 20 LCL strains during continuous long-term subculture up
to a passage number of 160. Out of 20 LCL strains, 17 proliferated up to a
passage number of 160, at which point LCLs are generally considered as
“immortalized”. The...
Transcriptional alteration of p53 related processes as a key factor for skeletal muscle characteristics in Sus scrofa
Elsevier BV - Tập 28 - Trang 565-573 - 2009
The pig could be a useful model to characterize molecular aspects determining
several delicate phenotypes because they have been bred for those
characteristics. The Korean native pig (KNP) is a regional breed in Korea that
was characterized by relatively high intramuscular fat content and reddish meat
color compared to other western breeds such as Yorkshire (YS). YS grew faster
and contained more ...
Retraction note: A hot pepper cDNA encoding ascorbate peroxidase is induced during the incompatible interaction with virus and bacteria
Elsevier BV - Tập 35 - Trang 175-175 - 2013
Control of TrkA-induced cell death by JNK activation and differential expression of TrkA upon DNA damage
Elsevier BV - Tập 30 - Trang 121-125 - 2010
TrkA, a receptor for nerve growth factor, plays a crucial role in neuronal cell
growth and differentiation. However, overactivation of TrkA signaling leads to
cell death in various cell types. TrkA-mediated cell death shows some
similarities to DNA damage-induced cell death. In this study, we examined how
TrkA-induced cell death is regulated upon DNA damage. Cytoplasmic expression of
TrkA protein ...
Ab ovo or de novo? Mechanisms of centriole duplication
Elsevier BV - Tập 27 - Trang 135-142 - 2009
The centrosome, an organelle comprising centrioles and associated pericentriolar
material, is the major microtubule organizing center in animal cells. For the
cell to form a bipolar mitotic spindle and ensure proper chromosome segregation
at the end of each cell cycle, it is paramount that the cell contains two and
only two centrosomes. Because the number of centrosomes in the cell is
determined b...
Rice small C2-domain proteins are phosphorylated by calcium-dependent protein kinase
Elsevier BV - Tập 35 - Trang 381-387 - 2013
We previously reported that OsERG1 and OsERG3 encode rice small C2-domain
proteins with different biochemical properties in Ca2+- and phospholipid-binding
assays. Os-ERG1 exhibited Ca2+-dependent phospholipid binding, which was not
observed with OsERG3. In the present study, we show that both OsERG1 and OsERG3
proteins exhibit oligomerization properties as determined by native
polyacrylamide gel e...
Calcineurin Regulates Coelomocyte Endocytosis via DYN-1 and CUP-4 in Caenorhabditis elegans
Elsevier BV - Tập 30 Số 3 - Trang 255-262 - 2010
Leukocyte common antigen-related (LAR) tyrosine phosphatase positively regulates osteoblast differentiation by modulating extracellular signal-regulated kinase (ERK) activation
Elsevier BV - Tập 30 - Trang 335-340 - 2010
Protein tyrosine phosphatases (PTPs) are pivotal regulators of key cellular
functions, including cell growth, differentiation, and adhesion. Previously, we
reported that leukocyte common antigen-related (LAR) tyrosine phosphatase
promotes osteoblast differentiation in MC3T3-E1 preosteoblast cells. In the
present study, the mechanism of the regulatory action of LAR on osteoblast
differentiation was...
Regulation of actin cytoskeleton dynamics in cells
Elsevier BV - Tập 29 - Trang 311-325 - 2010
The dynamic remolding of the actin cytoskeleton is a critical part of most
cellular activities, and malfunction of cytoskeletal proteins results in various
human diseases. The transition between two forms of actin, monomeric or G-actin
and filamentous or F-actin, is tightly regulated in time and space by a large
number of signaling, scaffolding and actin-binding proteins (ABPs). New ABPs are
const...
A new helicase assay based on graphene oxide for anti-viral drug development
Elsevier BV - Tập 35 - Trang 269-273 - 2013
Recently, graphene oxide (GO), one of the carbon nanomaterials, has received
much attention due to its unique physical and chemical properties and high
potential in many research areas, including applications as a biosensor and drug
delivery vehicle. Various GO-based biosensors have been developed, largely based
on its surface adsorption properties for detecting biomolecules, such as
nucleotides a...
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