Elsevier BV

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Recent advances in nanobiotechnology and high-throughput molecular techniques for systems biomedicine
Elsevier BV - Tập 36 - Trang 477-484 - 2013
Eung-Sam Kim, Eun Hyun Ahn, Euiheon Chung, Deok-Ho Kim
Nanotechnology-based tools are beginning to emerge as promising platforms for quantitative high-throughput analysis of live cells and tissues. Despite unprecedented progress made over the last decade, a challenge still lies in integrating emerging nanotechnology-based tools into macroscopic biomedical apparatuses for practical purposes in biomedical sciences. In this review, we discuss the recent ...... hiện toàn bộ
Identification of mouse MARVELD1 as a microtubule associated protein that inhibits cell cycle progression and migration
Elsevier BV - Tập 31 - Trang 267-274 - 2011
Fanli Zeng, Yanyan Tian, Shuliang Shi, Qiong Wu, Shanshan Liu, Hongxia Zheng, Lei Yue, Yu Li
MARVEL domain-containing 1 (MARVELD1) is a newly identified nuclear protein; however its function has not been clear until now. Here, we report that mouse MARVELD1 (mMARVELD1), which is highly conserved between mice and humans, exhibits cell cycle-dependent cellular localization. In NIH3T3 cells, MARVELD1 was observed in the nucleus and at the perinuclear region during interphase, but was localize...... hiện toàn bộ
A genetic screen for leaf movement mutants identifies a potential role for AGAMOUS-LIKE 6 (AGL6) in circadian-clock control
Elsevier BV - Tập 31 - Trang 281-287 - 2011
Seung Kwan Yoo, Sung Myun Hong, Jong Seob Lee, Ji Hoon Ahn
The circadian clock in plants regulates many important physiological and biological processes, including leaf movement. We have used an imaging system to genetically screen Arabidopsis seedlings for altered leaf movement with the aim of identifying a circadian clock gene. A total of 285 genes were selected from publicly available microarrays that showed an expression pattern similar to those of th...... hiện toàn bộ
Expression of p25, an Aberrant Cyclin-Dependent Kinase 5 Activator, Stimulates Basal Secretion in PC12 Cells
Elsevier BV - Tập 29 Số 1 - Trang 51-56 - 2010
Mi‐Young Son, Samuel Chung
Characterization of the structure and DNA complexity of mung bean mitochondrial nucleoids
Elsevier BV - Tập 31 - Trang 217-224 - 2011
Yih-Shan Lo, Lin-June Hsiao, Ning Cheng, Alexandra Litvinchuk, Hwa Dai
Electron microscopic images of mitochondrial nucleoids isolated from mung bean seedlings revealed a relatively homogeneous population of particles, each consisting of a chromatin-like structure associated with a membrane component. Association of F-actin with mitochondrial nucleoids was also observed. The mitochondrial nucleoid structure identified in situ showed heterogeneous genomic organization...... hiện toàn bộ
GAIP-interacting protein, C-terminus is involved in the induction of zinc-finger protein 143 in response to insulin-like growth factor-1 in colon cancer cells
Elsevier BV - Tập 32 Số 5 - Trang 415-419 - 2011
Paek, A. Rome, You, Hye Jin
Previously, we reported that the expression of zinc-finger protein 143 (ZNF143) was induced by insulin-like growth factor-1 (IGF-1) via reactive oxygen species (ROS)- and phosphatidylinositide-3-kinase (PI3-kinase)-linked pathways in colon cancer cells. Here, we investigated whether GAIP-interacting protein, C-terminus (GIPC), a binding partner of IGF-1R, is involved in ZNF143 expression through I...... hiện toàn bộ
A tdcA mutation reduces the invasive ability of Salmonella enterica serovar typhimurium
Elsevier BV - Tập 28 - Trang 389-395 - 2009
Minjeong Kim, Sangyong Lim, Dongho Kim, Hyon E. Choy, Sangryeol Ryu
We previously observed that the transcription of some flagellar genes decreased in Salmonella Typhimurium tdcA mutant, which is a gene encoding the transcriptional activator of the tdc operon. Since flagella-mediated bacterial motility accelerates the invasion of Salmonella, we have examined the effect of tdcA mutation on the invasive ability as well as the flagellar biosynthesis in S. Typhimurium...... hiện toàn bộ
Phân tích các locut tính trạng định lượng (QTLs) cho phản ứng nuôi cấy mô trong đậu nành (Glycine max (L.) Merr.) Dịch bởi AI
Elsevier BV - Tập 32 - Trang 337-342 - 2011
Chao Yang, Tuanjie Zhao, Deyue Yu, Junyi Gai
Các locut tính trạng định lượng (QTLs) kiểm soát phản ứng nuôi cấy mô trong đậu nành đã được phát hiện bằng cách sử dụng 184 dòng tái tổ hợp đồng hợp (RILs) được sinh ra từ hai giống: Kefeng No.1 và Nannong 1138-2. Bản đồ phân tử gồm 834 chỉ thị phân tử sử dụng quần thể này đã bao phủ một không gian là 2307,83 cM của bộ gen trong 24 nhóm liên kết. Hiệu suất nuôi cấy mô trong đậu nành được đánh giá...... hiện toàn bộ
#QTLs #nuôi cấy mô #đậu nành #Glycine max #kỹ thuật chọn lọc theo chỉ thị
The influence of HtrA expression on the growth of Streptococcus mutans during acid stress
Elsevier BV - Tập 29 - Trang 297-304 - 2010
Kyung-hee Kang, Jung-Sook Lee, Min Yoo, Ingnyol Jin
When proteins are damaged under stresses conditions, these proteins are either refolded or degraded by quality control system of molecular chaperones and protease. High-temperature requirement A (htrA) is of particular interest because it can perform the roles of both protease and a chaperone. HtrA plays an important role in maintaining the physiological homeostasis of bacteri against environmenta...... hiện toàn bộ
A novel sequence-based method of predicting protein DNA-binding residues, using a machine learning approach
Elsevier BV - Tập 30 - Trang 99-105 - 2010
Yudong Cai, ZhiSong He, Xiaohe Shi, Xiangying Kong, Lei Gu, Lu Xie
Protein-DNA interactions play an essential role in transcriptional regulation, DNA repair, and many vital biological processes. The mechanism of protein-DNA binding, however, remains unclear. For the study of many diseases, researchers must improve their understanding of the amino acid motifs that recognize DNA. Because identifying these motifs experimentally is expensive and time-consuming, it is...... hiện toàn bộ
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