Elsevier BV

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Sustained viral activity of epstein-Barr virus contributes to cellular immortalization of lymphoblastoid cell lines
Elsevier BV - Tập 27 - Trang 143-148 - 2009
Jae-Pil Jeon, Hye-Young Nam, Sung-Mi Shim, Bok-Ghee Han
EBV-transformed lymphoblastoid cell lines (LCLs) are used as a resource for human genetic, immunological, and pharmacogenomic studies. We investigated the biological activity of 20 LCL strains during continuous long-term subculture up to a passage number of 160. Out of 20 LCL strains, 17 proliferated up to a passage number of 160, at which point LCLs are generally considered as “immortalized”. The...... hiện toàn bộ
Transcriptional alteration of p53 related processes as a key factor for skeletal muscle characteristics in Sus scrofa
Elsevier BV - Tập 28 - Trang 565-573 - 2009
Seung-Soo Kim, Jung-Rok Kim, Jin-Kyoo Moon, Bong-Hwan Choi, Tae-Hun Kim, Kwan-Suk Kim, Jong-Joo Kim, Cheol-Koo Lee
The pig could be a useful model to characterize molecular aspects determining several delicate phenotypes because they have been bred for those characteristics. The Korean native pig (KNP) is a regional breed in Korea that was characterized by relatively high intramuscular fat content and reddish meat color compared to other western breeds such as Yorkshire (YS). YS grew faster and contained more ...... hiện toàn bộ
Retraction note: A hot pepper cDNA encoding ascorbate peroxidase is induced during the incompatible interaction with virus and bacteria
Elsevier BV - Tập 35 - Trang 175-175 - 2013
Tae Hyoung Yoo, Chang-Jin Park, Gil-je Lee, Ryoung Shin, Ji-Hyun Yun, Ki-Jeong Kim, Ki-Hyeong Rhee, Kyung-Hee Paek
Control of TrkA-induced cell death by JNK activation and differential expression of TrkA upon DNA damage
Elsevier BV - Tập 30 - Trang 121-125 - 2010
Eun Joo Jung, Deok Ryong Kim
TrkA, a receptor for nerve growth factor, plays a crucial role in neuronal cell growth and differentiation. However, overactivation of TrkA signaling leads to cell death in various cell types. TrkA-mediated cell death shows some similarities to DNA damage-induced cell death. In this study, we examined how TrkA-induced cell death is regulated upon DNA damage. Cytoplasmic expression of TrkA protein ...... hiện toàn bộ
Rice small C2-domain proteins are phosphorylated by calcium-dependent protein kinase
Elsevier BV - Tập 35 - Trang 381-387 - 2013
Chang Ho Kang, Byeong Cheol Moon, Hyeong Cheol Park, Sung Cheol Koo, Yong Hun Chi, Yong Hwa Cheong, Byung-Dae Yoon, Sang Yeol Lee, Cha Young Kim
We previously reported that OsERG1 and OsERG3 encode rice small C2-domain proteins with different biochemical properties in Ca2+- and phospholipid-binding assays. Os-ERG1 exhibited Ca2+-dependent phospholipid binding, which was not observed with OsERG3. In the present study, we show that both OsERG1 and OsERG3 proteins exhibit oligomerization properties as determined by native polyacrylamide gel e...... hiện toàn bộ
Ab ovo or de novo? Mechanisms of centriole duplication
Elsevier BV - Tập 27 - Trang 135-142 - 2009
Jadranka Loncarek, Alexey Khodjakov
The centrosome, an organelle comprising centrioles and associated pericentriolar material, is the major microtubule organizing center in animal cells. For the cell to form a bipolar mitotic spindle and ensure proper chromosome segregation at the end of each cell cycle, it is paramount that the cell contains two and only two centrosomes. Because the number of centrosomes in the cell is determined b...... hiện toàn bộ
Calcineurin Regulates Coelomocyte Endocytosis via DYN-1 and CUP-4 in Caenorhabditis elegans
Elsevier BV - Tập 30 Số 3 - Trang 255-262 - 2010
Hyun-Ok Song, Jungsoo Lee, Yon Ju Ji, Meenakshi Dwivedi, Jeong Hoon Cho, Byung-Jae Park, Joohong Ahnn
Leukocyte common antigen-related (LAR) tyrosine phosphatase positively regulates osteoblast differentiation by modulating extracellular signal-regulated kinase (ERK) activation
Elsevier BV - Tập 30 - Trang 335-340 - 2010
Won Kon Kim, Kwang-Hee Bae, Hye-Ryung Choi, Do-Hyung Kim, Kwang-Soo Choi, Yee Sook Cho, Hee Dai Kim, Sung Goo Park, Byoung Chul Park, Yong Ko, Sang Chul Lee
Protein tyrosine phosphatases (PTPs) are pivotal regulators of key cellular functions, including cell growth, differentiation, and adhesion. Previously, we reported that leukocyte common antigen-related (LAR) tyrosine phosphatase promotes osteoblast differentiation in MC3T3-E1 preosteoblast cells. In the present study, the mechanism of the regulatory action of LAR on osteoblast differentiation was...... hiện toàn bộ
A new helicase assay based on graphene oxide for anti-viral drug development
Elsevier BV - Tập 35 - Trang 269-273 - 2013
Hongje Jang, Soo-Ryoon Ryoo, Min Jae Lee, Sang Woo Han, Dal-Hee Min
Recently, graphene oxide (GO), one of the carbon nanomaterials, has received much attention due to its unique physical and chemical properties and high potential in many research areas, including applications as a biosensor and drug delivery vehicle. Various GO-based biosensors have been developed, largely based on its surface adsorption properties for detecting biomolecules, such as nucleotides a...... hiện toàn bộ
Recent advances in nanobiotechnology and high-throughput molecular techniques for systems biomedicine
Elsevier BV - Tập 36 - Trang 477-484 - 2013
Eung-Sam Kim, Eun Hyun Ahn, Euiheon Chung, Deok-Ho Kim
Nanotechnology-based tools are beginning to emerge as promising platforms for quantitative high-throughput analysis of live cells and tissues. Despite unprecedented progress made over the last decade, a challenge still lies in integrating emerging nanotechnology-based tools into macroscopic biomedical apparatuses for practical purposes in biomedical sciences. In this review, we discuss the recent ...... hiện toàn bộ
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