Drugs - Real World Outcomes
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Trends in the Use of Sedative-Hypnotics, Opioids, and Neuromuscular Blockers in Hospitalized Patients During the COVID-19 Pandemic: Observational Retrospective Study
Drugs - Real World Outcomes - Tập 9 - Trang 629-638 - 2022
The coronavirus disease 2019 (COVID-19) pandemic has increased the use of drugs
administered for mechanical ventilation, leading to shortages in some countries.
The aim was to identify trends in the consumption of sedatives, hypnotics,
neuromuscular blockers, and opioids used for anesthetic induction and deep
sedation in hospitals in Colombia. This was a descriptive, longitudinal, and
retrospectiv...
Self-Reported Medication Adherence Among Older People Admitted to Hospital: A Descriptive Study
Drugs - Real World Outcomes - Tập 10 - Trang 23-29 - 2023
Poor medication adherence is prevalent among older people. To optimize
therapeutic outcomes, it is crucial to understand the underlying causes and
perceptions. We aimed to investigate the extent of self-reported medication
adherence and associated factors among older people admitted to hospital.
Individuals living at home aged ≥ 75 years with an emergency admission at a
university hospital between...
Adverse Events Associated with Use of Digoxin Immune Fab Reported to the US Food and Drug Administration Adverse Event Reporting System, 1986–2019
Drugs - Real World Outcomes - Tập 8 Số 2 - Trang 253-262 - 2021
Digoxin immune fab products, DigiBind and DigiFab, are antidotes for the
treatment of patients with life-threatening or potentially life-threatening
digoxin toxicity or overdose. Although approved by the US Food and Drug
Administration (FDA) in 1986 (DigiBind) and 2001 (DigiFab), there remains a
paucity of literature describing the safety of these products in the
postmarketing setting. We sought t...
Effectiveness of Saccharomyces boulardii CNCM I-745 in Adult Indian Patients with Diarrhoea: A Real-world, Multicentre, Retrospective, Comparative Study
Drugs - Real World Outcomes - - 2024
Multiple clinical studies have described the benefits of probiotic Saccharomyces
boulardii (S. boulardii) CNCM I-745 against diarrhoea, but the real-world
evidence supporting its use is lacking. To evaluate effectiveness of the S.
boulardii CNCM I-745 group in a real-world setting. This was an electronic
medical record (EMR)-based, retrospective, multicentre, comparative study in
Indian adult pati...
Prescription of Sedative Drugs During Hospital Stay: A Swiss Prospective Study
Drugs - Real World Outcomes - Tập 4 - Trang 225-234 - 2017
In recent years, the number of prescriptions for sedative drugs has increased
significantly, as has their long-term use. Moreover, sedative use is frequently
initiated during hospital stays. This study aimed to describe new prescriptions
of sedative drugs during hospital stays and evaluate their maintenance as
discharge medication. This observational prospective study took place in an
internal med...
Signal Detection and Assessment of Herb–Drug Interactions: Saudi Food and Drug Authority SFDA Experience
Drugs - Real World Outcomes - - Trang 1-9 - 2023
Numerous investigations on herbal medicine that have been undertaken in the past
several years demonstrate the general acceptance of its safety. The Saudi Food
and Drug Authority (SFDA) established the Herb–Drug Interaction (HDI) project to
detect and assess potential HDIs to ensure safety. The aim is to detect safety
signals and assess them based on available evidence. First, SFDA-registered
herb...
Prevalence and Associated Factors of Drug-Related Problems Among Older People: A Cross-Sectional Study at King Chulalongkorn Memorial Hospital in Bangkok
Drugs - Real World Outcomes - Tập 8 - Trang 73-84 - 2020
The use of multiple medications and altered pharmacokinetics/pharmacodynamics
may lead to drug-related problems in members of the older population. The aim of
this study is to evaluate the prevalence of, and factors related to,
drug-related problems in older urban-living Thai people. We conducted a
cross-sectional study involving 466 participants (aged ≥ 65 years) whose
first-time health screening...
Efficacy and Safety of Long-Term Treatment with Stiripentol in Children and Adults with Drug-Resistant Epilepsies: A Retrospective Cohort Study of 196 Patients
Drugs - Real World Outcomes - Tập 9 Số 3 - Trang 451-461 - 2022
Itraconazole Contaminated with Rilmazafone in Japan: A Retrospective Analysis Using the Japanese Adverse Drug Event Report Database
Drugs - Real World Outcomes - Tập 9 - Trang 315-319 - 2022
In early December 2020, the antifungal medication, itraconazole (ITCZ), was
mistakenly contaminated with rilmazafone in Japan. Healthcare professionals
reported adverse drug reaction reports associated with ITCZ and included central
nervous system-depression symptoms such as dizziness, lightheadedness, loss of
consciousness, and intense drowsiness. We examined ITCZ-associated suspicious
cases usin...
Polypharmacy in Australian Veterans with Post-traumatic Stress Disorder upon Admission to a Mental Health Facility: A Retrospective Chart Review
Drugs - Real World Outcomes - Tập 9 - Trang 347-357 - 2022
Polypharmacy increases the risk of adverse drug events and drug–drug
interactions, and contributes to falls, hospital admissions, morbidity and
mortality. Veterans with post-traumatic stress disorder often have psychological
and physical comorbidities, increasing the likelihood of general and
psychotropic polypharmacy. This study investigates the prevalence of general and
psychotropic polypharmacy...
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