Digestive Diseases and Sciences

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Delta-Opioid Receptor mRNA Expression and Immunohistochemical Localization in Porcine Ileum
Digestive Diseases and Sciences - Tập 43 - Trang 1402-1410 - 1998
David R. Brown, Sutthasinee Poonyachoti, Mark A. Osinski, Teresa R. Kowalski, Mary S. Pampusch, Robert P. Elde, Michael P. Murtaugh
Opiates have potent antidiarrheal actions thatare mediated in part by delta-opioid receptors (DOR). Weexamined DOR localization within subregions of porcineileum, a tissue analogous to human small bowel. A partial cDNA sequence for porcine DOR wasobtained after reverse transcription-polymerase chainreaction cloning of forebrain RNA; it encoded the end oftransmembrane domain 1 through the beginning...... hiện toàn bộ
Effect of experimental cold pain stress on gastroesophageal junction
Digestive Diseases and Sciences - Tập 39 - Trang 641-647 - 1994
P. Zacchi, F. Mearin, J.-R. Malagelada
The impact of stress on gastroesophageal reflux and antireflux mechanisms remains largely unexplored. To a major extent, reflux depends on a balance between gastroesophageal junction resistance to flow and gastric tone. We hypothesized that these two forces could be differently affected by stress, and to test the hypothesis we quantified in 10 healthy volunteers the effect of an acute stressful st...... hiện toàn bộ
Peritoneoscopy: Its value as a diagnostic aid
Digestive Diseases and Sciences - Tập 5 Số 11 - Trang 931-934 - 1960
Alan R. Aronson, Gerald W. Parker
Suppression of Ulcerative Colitis in Mice by Orally Available Inhibitors of Sphingosine Kinase
Digestive Diseases and Sciences - Tập 53 - Trang 997-1012 - 2007
Lynn W. Maines, Leo R. Fitzpatrick, Kevin J. French, Yan Zhuang, Zuping Xia, Staci N. Keller, John J. Upson, Charles D. Smith
A critical step in the mechanism of action of inflammatory cytokines is the stimulation of sphingolipid metabolism, including activation of sphingosine kinase (SK), which produces the mitogenic and proinflammatory lipid sphingosine 1-phosphate (S1P). We have developed orally bioavailable compounds that effectively inhibit SK activity in vitro in intact cells and in cancer models in vivo. In this s...... hiện toàn bộ
Occupational Mortality from Squamous Cell Carcinoma of the Esophagus in the United States During 1991–1996
Digestive Diseases and Sciences - Tập 47 - Trang 568-572 - 2002
Claudia Cucino, Amnon Sonnenberg
The epidemiology of esophageal squamous cell cancer has remained poorly understood. The occupational distribution of this cancer may provide clues about its yet unknown etiology. Data files from the National Center for Health Statistics (NCHS) of the United States offer a unique source to study causes of death, broken down by occupation and industry. The number of deaths from esophageal cancer was...... hiện toàn bộ
Value of proctoscopy in the diagnosis of amebiasis
Digestive Diseases and Sciences - Tập 10 - Trang 365-366 - 1943
Raymond J. Jackman, Wilford L. Cooper
A study of 115 consecutive patients who had amebic dysentery was carried out for the purpose of determining how much value proctoscopy has in the diagnosis of the condition. Ulceration of the lower part of the bowel, suggestive of amebiasis, as determined by proctoscopy, was found in 20.8 per cent of the cases of amebic dysentery. Biopsy and scrapings from the ulcers at the time of proctoscopy aff...... hiện toàn bộ
Endoscopic biopsy is diagnostic in gastric antral vascular ectasia
Digestive Diseases and Sciences - Tập 34 Số 6 - Trang 885-888 - 1989
John H. Gilliam, Kim R. Geisinger, Wallace C. Wu, Noel Weidner, Joel E. Richter
Endoscopic Evaluation of PET/CT Abnormalities in the Gastrointestinal Tract: Yield and Approach
Digestive Diseases and Sciences - - Trang 1-10 - 2023
Harry Trieu, Sadie De Silva, Saro Manoukian, Anand Rajan, Rifat Mannan, Yu Liang, Jeffrey K. Lee, James Lin, Trilokesh D. Kidambi
Unexpected hypermetabolic activity is often encountered in the gastrointestinal tract when PET/CT is performed for various indications, prompting endoscopic evaluation. Our aim was to characterize the types of lesions seen in segments of the gastrointestinal tract with unexpected PET/CT abnormalities as well as clinically significant lesions seen on endoscopy which did not produce a PET/CT abnorma...... hiện toàn bộ
A Case of Thiopurine-Induced Acute Myocarditis in a Patient with Ulcerative Colitis
Digestive Diseases and Sciences - Tập 61 - Trang 3633-3634 - 2016
Anastasiya Latushko, Leyla J. Ghazi
Biliary Complications Following Liver Transplantation
Digestive Diseases and Sciences - Tập 55 - Trang 1540-1546 - 2010
Walid S. Ayoub, Carlos O. Esquivel, Paul Martin
The aphorism that reconstruction of the biliary anastomosis is the “Achilles heel” of liver transplantation remains valid as biliary complications following liver transplantation remain a major source of morbidity with an incidence of 5–32%. Biliary complications include biliary strictures, biliary leaks, and stones. Biliary strictures can be divided into anastomotic and non-anastomotic. The manag...... hiện toàn bộ
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