Diagnostics

Công bố khoa học tiêu biểu

* Dữ liệu chỉ mang tính chất tham khảo

Sắp xếp:  
Screen Printed Carbon Electrode Based Electrochemical Immunosensor for the Detection of Dengue NS1 Antigen
Diagnostics - Tập 4 Số 4 - Trang 165-180
Om Parkash, Chan Yean Yean, Rafidah Hanim Shueb
An electrochemical immunosensor modified with the streptavidin/biotin system on screen printed carbon electrodes (SPCEs) for the detection of the dengue NS1 antigen was developed in this study. Monoclonal anti-NS1 capture antibody was immobilized on streptavidin-modified SPCEs to increase the sensitivity of the assay. Subsequently, a direct sandwich enzyme linked immunosorbent assay (ELISA...... hiện toàn bộ
Skin Lesion Segmentation and Multiclass Classification Using Deep Learning Features and Improved Moth Flame Optimization
Diagnostics - Tập 11 Số 5 - Trang 811
Muhammad Attique Khan, Muhammad Sharif, Tallha Akram, Robertas Damaševičius, Rytis Maskeliūnas
Manual diagnosis of skin cancer is time-consuming and expensive; therefore, it is essential to develop automated diagnostics methods with the ability to classify multiclass skin lesions with greater accuracy. We propose a fully automated approach for multiclass skin lesion segmentation and classification by using the most discriminant deep features. First, the input images are initially en...... hiện toàn bộ
Diagnostic Value of DAPK Methylation for Nasopharyngeal Carcinoma: Meta-Analysis
Diagnostics - Tập 13 Số 18 - Trang 2926 - 2023
Lao, Thuan Duc, Truong, Phuong Kim, Le, Thuy Ai Huyen
Background: Methylation of DAPK has been reported to play a key role in the initiation and progression of nasopharyngeal cancer. However, there are differences between the studies on it. This meta-analysis was performed to evaluate the diagnostic value of DAPK promoter methylation for NPC. Method: The study method involves the systematic research of eligible studies based on criteria. The frequenc...... hiện toàn bộ
Gene Mutation Spectrum among Alpha-Thalassaemia Patients in Northeast Peninsular Malaysia
Diagnostics - Tập 13 Số 5 - Trang 894
Divashini Vijian, Wan Suriana Wan Ab Rahman, Thirumulu Ponnuraj Kannan, Zefarina Zulkafli, Rosnah Bahar, Norafiza Mohd Yasin, Syahzuwan Hassan, Ezalia Esa
(1) Background: Alpha (α)-thalassaemia is a genetic disorder that affects 5% of the world population. Deletional or nondeletional mutations of one or both HBA1 and HBA2 on chromosome 16 will result in reduced production of α-globin chains, a component of haemoglobin (Hb) that is required for the formation of red blood cells (RBCs). This study aimed to determine the prevalence, haematologic...... hiện toàn bộ
CCNE1 Amplification as a Predictive Biomarker of Chemotherapy Resistance in Epithelial Ovarian Cancer
Diagnostics - Tập 10 Số 5 - Trang 279
J Górski, Frederick R. Ueland, Jill Kolesar
Ovarian cancer is the most-deadly gynecologic malignancy, with greater than 14,000 women expected to succumb to the disease this year in the United States alone. In the front-line setting, patients are treated with a platinum and taxane doublet. Although 40–60% of patients achieve complete clinical response to first-line chemotherapy, 25% are inherently platinum-resistant or refractory wit...... hiện toàn bộ
Commercial Smartphone-Based Devices and Smart Applications for Personalized Healthcare Monitoring and Management
Diagnostics - Tập 4 Số 3 - Trang 104-128
Sandeep Kumar Vashist, E. Marion Schneider, John H. T. Luong
Smartphone-based devices and applications (SBDAs) with cost effectiveness and remote sensing are the most promising and effective means of delivering mobile healthcare (mHealthcare). Several SBDAs have been commercialized for the personalized monitoring and/or management of basic physiological parameters, such as blood pressure, weight, body analysis, pulse rate, electrocardiograph, blood ...... hiện toàn bộ
Comparison of 1-Ethyl-3-(3-Dimethylaminopropyl) Carbodiimide Based Strategies to Crosslink Antibodies on Amine-Functionalized Platforms for Immunodiagnostic Applications
Diagnostics - Tập 2 Số 3 - Trang 23-33
Sandeep Kumar Vashist
1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) alone, and in combination with N-hydroxysuccinimide (NHS) or sulfoNHS were employed for crosslinking anti-human fetuin A (HFA) antibodies on 3-aminopropyltriethoxysilane (APTES)-functionalized surface plasmon resonance (SPR) gold chip and 96-well microtiter plate. The SPR immunoassay and sandwich enzyme linked immunosorbent immunoassay (...... hiện toàn bộ
Renal Complications Related to Checkpoint Inhibitors: Diagnostic and Therapeutic Strategies
Diagnostics - Tập 11 Số 7 - Trang 1187
Julie Bellière, Julien Mazières, Nicolás Meyer, Leila Chebane, Fabien Despas
Immune checkpoint inhibitors (ICI) targeting CTLA-4 and the PD-1/PD-L1 axis have unprecedentedly improved global prognosis in several types of cancers. However, they are associated with the occurrence of immune-related adverse events. Despite their low incidence, renal complications can interfere with the oncologic strategy. The breaking of peripheral tolerance and the emergence of auto- o...... hiện toàn bộ
Development of Multiplexed Infectious Disease Lateral Flow Assays: Challenges and Opportunities
Diagnostics - Tập 7 Số 3 - Trang 51
Khayriyyah Mohd Hanafiah, Norsyahida Arifin, Yazmin Bustami, Rahmah Noordin, Mary L. Garcia, David A. Anderson
Lateral flow assays (LFAs) are the mainstay of rapid point-of-care diagnostics, with the potential to enable early case management and transform the epidemiology of infectious disease. However, most LFAs only detect single biomarkers. Recognizing the complex nature of human disease, overlapping symptoms and states of co-infections, there is increasing demand for multiplexed systems that ca...... hiện toàn bộ
Feasibility of Direct Sputum Molecular Testing for Drug Resistance as Part of Tuberculosis Clinical Trials Eligibility Screening
Diagnostics - - 2019
Alipanah, Narges, Shete, Priya B., Nguyen, Hanh, Nguyen, Nhung Viet, Luu, Lien, Pham, Thuong, Nguyen, Hung, Nguyen, Phuong, Tran, Minh Chi, Pham, Nam, Phan, Ha, Phillips, Patrick P.J., Cattamanchi, Adithya, Nahid, Payam
A rapid diagnosis of drug-resistant tuberculosis (TB) is critical for early initiation of effective therapy. Molecular testing with line probe assays (MTBDRplus and MTBDRsl) on culture isolates has been available for some time and significantly reduces the time to diagnosis of drug resistance. However, routine use of this test directly on sputum is less common. As part of enrollment screening proc...... hiện toàn bộ
Tổng số: 27   
  • 1
  • 2
  • 3