Diagnostics
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Screen Printed Carbon Electrode Based Electrochemical Immunosensor for the Detection of Dengue NS1 AntigenAn electrochemical immunosensor modified with the streptavidin/biotin system on screen printed carbon electrodes (SPCEs) for the detection of the dengue NS1 antigen was developed in this study. Monoclonal anti-NS1 capture antibody was immobilized on streptavidin-modified SPCEs to increase the sensitivity of the assay. Subsequently, a direct sandwich enzyme linked immunosorbent assay (ELISA... ...
Diagnostics - Tập 4 Số 4 - Trang 165-180
Feasibility of Direct Sputum Molecular Testing for Drug Resistance as Part of Tuberculosis Clinical Trials Eligibility Screening
Diagnostics - - 2019
A rapid diagnosis of drug-resistant tuberculosis (TB) is critical for early initiation of effective therapy. Molecular testing with line probe assays (MTBDRplus and MTBDRsl) on culture isolates has been available for some time and significantly reduces the time to diagnosis of drug resistance. However, routine use of this test directly on sputum is less common. As part of enrollment screening proc......
Deep-EEG: An Optimized and Robust Framework and Method for EEG-Based Diagnosis of Epileptic SeizureDetecting brain disorders using deep learning methods has received much hype during the last few years. Increased depth leads to more computational efficiency, accuracy, and optimization and less loss. Epilepsy is one of the most common chronic neurological disorders characterized by repeated seizures. We have developed a deep learning model using Deep convolutional Autoencoder—Bidirection... ...
Diagnostics - Tập 13 Số 4 - Trang 773
COVID-19 Serological Tests: How Well Do They Actually Perform?In only a few months after initial discovery in Wuhan, China, SARS-CoV-2 and the associated coronavirus disease 2019 (COVID-19) have become a global pandemic causing significant mortality and morbidity and implementation of strict isolation measures. In the absence of vaccines and effective therapeutics, reliable serological testing must be a key element of public health policy to control ... ...
Diagnostics - Tập 10 Số 7 - Trang 453
Fully Automated Breast Density Segmentation and Classification Using Deep LearningBreast density estimation with visual evaluation is still challenging due to low contrast and significant fluctuations in the mammograms’ fatty tissue background. The primary key to breast density classification is to detect the dense tissues in the mammographic images correctly. Many methods have been proposed for breast density estimation; nevertheless, most of them are not fully automat... ...
Diagnostics - Tập 10 Số 11 - Trang 988
Skin Lesion Segmentation and Multiclass Classification Using Deep Learning Features and Improved Moth Flame OptimizationManual diagnosis of skin cancer is time-consuming and expensive; therefore, it is essential to develop automated diagnostics methods with the ability to classify multiclass skin lesions with greater accuracy. We propose a fully automated approach for multiclass skin lesion segmentation and classification by using the most discriminant deep features. First, the input images are initially en... ...
Diagnostics - Tập 11 Số 5 - Trang 811
Brain-Derived Neurotrophic Factor (BDNF) and Translocator Protein (TSPO) as Diagnostic Biomarkers for Acute Ischemic Stroke
Diagnostics - Tập 13 Số 13 - Trang 2298 - 2023
Brain-derived neurotrophic factor (BDNF) interacts with tropomyosin-related kinase B (TrkB) to promote neuronal growth, survival, differentiation, neurotransmitter release, and synaptic plasticity. The translocator protein (TSPO) is known to be found in arterial plaques, which are a symptom of atherosclerosis and a contributory cause of ischemic stroke. This study aims to determine the diagnostic ......
Bioanalytical Performance of a New Particle-Enhanced Method for Measuring ProcalcitoninWe report the analytical performances of two particle-enhanced (PETIA) methods for measuring procalcitonin (PCT), the Diazyme PCT and the new DiaSys PCT assay, and their concordance of values with BRAHMS PCT Kryptor©. The total imprecisions onto two control levels and one serum pool were for DiaSys 5.42%, 3.3% and 7.53% and for Diazyme 10.7%, 2.9% and 13.23%, respectively. The limit of bla... ...
Diagnostics - Tập 10 Số 7 - Trang 461
Comparison of Procalcitonin Assays on KRYPTOR and LIAISON® XL AnalyzersOur laboratory performs procalcitonin (PCT) assays on a Brahms KRYPTOR analyzer with the Brahms PCT sensitive Kryptor kit. In this study, we wanted to compare the assays obtained in this way with the ones performed on the LIAISON® XL. From January to May 2017, 171 samples were analyzed, of which 65 from female patients (age: 22–98 years) and 106 from male patients (age: 16–97 years). The P... ...
Diagnostics - Tập 9 Số 3 - Trang 94
Diagnostic Value of DAPK Methylation for Nasopharyngeal Carcinoma: Meta-Analysis
Diagnostics - Tập 13 Số 18 - Trang 2926 - 2023
Background: Methylation of DAPK has been reported to play a key role in the initiation and progression of nasopharyngeal cancer. However, there are differences between the studies on it. This meta-analysis was performed to evaluate the diagnostic value of DAPK promoter methylation for NPC. Method: The study method involves the systematic research of eligible studies based on criteria. The frequenc......
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